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The BLUPF90 family of programs is a statistical software package used in
quantitative genetics Quantitative genetics deals with phenotypes that vary continuously (such as height or mass)—as opposed to discretely identifiable phenotypes and gene-products (such as eye-colour, or the presence of a particular biochemical). Both branches u ...
for
animal Animals are multicellular, eukaryotic organisms in the Kingdom (biology), biological kingdom Animalia. With few exceptions, animals Heterotroph, consume organic material, Cellular respiration#Aerobic respiration, breathe oxygen, are Motilit ...
and
plant breeding Plant breeding is the science of changing the traits of plants in order to produce desired characteristics. It has been used to improve the quality of nutrition in products for humans and animals. The goals of plant breeding are to produce cro ...
. It can fit
mixed model A mixed model, mixed-effects model or mixed error-component model is a statistical model containing both fixed effects and random effects. These models are useful in a wide variety of disciplines in the physical, biological and social sciences. ...
s using
restricted maximum likelihood In statistics, the restricted (or residual, or reduced) maximum likelihood (REML) approach is a particular form of maximum likelihood estimation that does not base estimates on a maximum likelihood fit of all the information, but instead uses a like ...
as well as
Gibbs sampling In statistics, Gibbs sampling or a Gibbs sampler is a Markov chain Monte Carlo (MCMC) algorithm for obtaining a sequence of observations which are approximated from a specified multivariate probability distribution, when direct sampling is dif ...
to estimate variance components, and predict breeding values via
best linear unbiased prediction In statistics, best linear unbiased prediction (BLUP) is used in linear mixed models for the estimation of random effects. BLUP was derived by Charles Roy Henderson in 1950 but the term "best linear unbiased predictor" (or "prediction") seems not ...
(BLUP). Coded in Fortran, it can perform
genomic selection Genomic Selection (GS) predicts the breeding values of an offspring in a population by associating their traits (i.e. resistance to pests) with their high-density genetic marker scores. GS is a method proposed to address deficiencies of marker-assi ...
on hundreds of thousands of genotyped individuals. Compiled versions of BLUPF90 are freely available for research, and can be used on Linux, Microsoft Windows and Mac OS X. There also exists an add-on to
R (programming language) R is a programming language for statistical computing and graphics supported by the R Core Team and the R Foundation for Statistical Computing. Created by statisticians Ross Ihaka and Robert Gentleman, R is used among data miners, bioinform ...
.https://famuvie.github.io/breedR/
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References


External links


BLUPF90 home page
Statistical software {{science-software-stub