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Butalamine is a
The halogenation of benzamidoxime 32-90-1 22-31-1(1) with chlorine and subsequent reaction with
vasodilator
Vasodilation is the widening of blood vessels. It results from relaxation of smooth muscle cells within the vessel walls, in particular in the large veins, large arteries, and smaller arterioles. The process is the opposite of vasoconstriction, ...
.
Synthesis
Check with imolamine (alternate nitrogen reacts)
The halogenation of benzamidoxime 32-90-1 22-31-1(1) with chlorine and subsequent reaction with cyanamide
Cyanamide is an organic compound with the chemical formula, formula carbon, Cnitrogen, N2hydrogen, H2. This white solid is widely used in agriculture and the production of pharmaceuticals and other organic compounds. It is also used as an alcoho ...
(3) gives 5-amino-3-phenyl-1,2,4-oxadiazole 663-37-4(4). Base catalyzed alkylation with dibutylaminoethyl chloride 3422-90-7(5) completes the synthesis of butalamine (6).
References
Vasodilators Oxadiazoles {{cardiovascular-drug-stub