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Johanna Budwig (1908 – 2003) was a German
biochemist Biochemists are scientists who are trained in biochemistry. They study chemical processes and chemical transformations in living organisms. Biochemists study DNA, proteins and Cell (biology), cell parts. The word "biochemist" is a portmanteau of ...
,
alternative cancer treatment Alternative cancer treatment describes any cancer treatment or practice that is not part of the conventional standard of cancer care. These include special diets and exercises, chemicals, herbs, devices, and manual procedures. Most alternative ...
advocate and writer.Kerckhof, Annette. (2020). ''Budwig, Johanna (1908–2003)''. In ''Wichtige Frauen in der Naturheilkunde''. Springer. pp. 65-69. Budwig was a
pharmacist A pharmacist, also known as a chemist (Commonwealth English) or a druggist (North American and, archaically, Commonwealth English), is a healthcare professional who prepares, controls and distributes medicines and provides advice and instructi ...
and held
doctorate A doctorate (from Latin ''docere'', "to teach"), doctor's degree (from Latin ''doctor'', "teacher"), or doctoral degree is an academic degree awarded by universities and some other educational institutions, derived from the ancient formalism ''l ...
degrees in
physics Physics is the natural science that studies matter, its fundamental constituents, its motion and behavior through space and time, and the related entities of energy and force. "Physical science is that department of knowledge which r ...
and
chemistry Chemistry is the science, scientific study of the properties and behavior of matter. It is a natural science that covers the Chemical element, elements that make up matter to the chemical compound, compounds made of atoms, molecules and ions ...
. Based on her research on
fatty acid In chemistry, particularly in biochemistry, a fatty acid is a carboxylic acid with an aliphatic chain, which is either saturated or unsaturated. Most naturally occurring fatty acids have an unbranched chain of an even number of carbon atoms, fr ...
s she developed a
lacto-vegetarian A lacto-vegetarian (sometimes referred to as a lactarian; from the Latin root lact-, ''milk'') diet is a diet that abstains from the consumption of meat as well as eggs, while still consuming dairy products such as milk, cheese, yogurt, butter, ...
diet that she believed was useful in the
treatment of cancer Cancer can be treated by surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy (including immunotherapy such as monoclonal antibody therapy) and synthetic lethality, most commonly as a series of separate treatments (e.g. ...
. There is no evidence that this or other "anti-cancer" diets are effective, and the Budwig diet may be actively harmful.


Biography

Budwig was born in
Essen Essen (; Latin: ''Assindia'') is the central and, after Dortmund, second-largest city of the Ruhr, the largest urban area in Germany. Its population of makes it the fourth-largest city of North Rhine-Westphalia after Cologne, Düsseldorf and D ...
and at the age of 16 joined the Kaiserswerth Deaconess Institute. She studied pharmacy in
Königsberg Königsberg (, ) was the historic Prussian city that is now Kaliningrad, Russia. Königsberg was founded in 1255 on the site of the ancient Old Prussian settlement ''Twangste'' by the Teutonic Knights during the Northern Crusades, and was named ...
and
Münster Münster (; nds, Mönster) is an independent city (''Kreisfreie Stadt'') in North Rhine-Westphalia, Germany. It is in the northern part of the state and is considered to be the cultural centre of the Westphalia region. It is also a state distr ...
where she met her mentor Prof. Hans Kaufmann the founder of the German Institute for Fat Research. She worked under Kaufmann as a research assistant and completed her doctorate in 1939. While working as a researcher at the German Federal Health Office she noted many
cancer drugs Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents or alkylating agents) as part of a standardized chemotherapy regimen. Chemotherap ...
being evaluated in the 1950s contained sulphydryl groups. Budwig believed sulphydryl compounds were important to cellular
metabolism Metabolism (, from el, μεταβολή ''metabolē'', "change") is the set of life-sustaining chemical reactions in organisms. The three main functions of metabolism are: the conversion of the energy in food to energy available to run cell ...
and
cellular respiration Cellular respiration is the process by which biological fuels are oxidised in the presence of an inorganic electron acceptor such as oxygen to produce large amounts of energy, to drive the bulk production of ATP. Cellular respiration may be des ...
. Budwig researched the theory that a low oxygen environment would develop in the absence of sulphydryl groups and/or fatty acid partners that would encourage the proliferation of cancerous cells. With Kaufmann she developed
paper chromatography Paper chromatography is an analytical method used to separate coloured chemicals or substances. It is now primarily used as a teaching tool, having been replaced in the laboratory by other chromatography methods such as thin-layer chromatography ...
techniques to identify and quantify fatty acids. Budwig used these techniques to compare the fatty acid profiles of sick and healthy individuals. In 1950, Budwig and Kaufmann presented their findings at the International Fat Congress on "New approaches in fat analysis". She argued that highly heated and chemically modified fats found primarily in
margarine Margarine (, also , ) is a spread used for flavoring, baking, and cooking. It is most often used as a substitute for butter. Although originally made from animal fats, most margarine consumed today is made from vegetable oil. The spread was orig ...
were dangerous to human health. In 1951, Budwig was chief expert for pharmaceuticals and fats in the Federal Institute for Fat Research but resigned over controversy due to her critical statements about
trans fatty acids Trans fat, also called trans-unsaturated fatty acids, or trans fatty acids, is a type of unsaturated fat that naturally occurs in small amounts in meat and milk fat. It became widely produced as an unintentional byproduct in the industrial p ...
. Bugwig came to the conclusion that industrial processed fats were a strain on health and caused cardiovascular disease and cancer, whilst polyunsaturated fatty acids were protective. She argued that linseed oil which contains
alpha-Linolenic acid ''alpha''-Linolenic acid (ALA), also known as α-Linolenic acid (from Greek ''alpha'' meaning "first" and ''linon'' meaning flax), is an ''n''−3, or omega-3, essential fatty acid. ALA is found in many seeds and oils, including flaxseed, waln ...
, an essential omega-3 fatty acid and sulphur proteins in the form of low-fat
quark A quark () is a type of elementary particle and a fundamental constituent of matter. Quarks combine to form composite particles called hadrons, the most stable of which are protons and neutrons, the components of atomic nuclei. All commonly o ...
or cottage cheese are a great importance in the diet. She became known for her "Budwig Creme", for which linseed oil, milk and low-fat quark are stirred together until no oil is left. Bugwig died in
Freudenstadt Freudenstadt ( Swabian: ''Fraidestadt'') is a town in Baden-Württemberg in southern Germany. It is capital of the district Freudenstadt. The closest population centres are Offenburg to the west (approx. 36 km away) and Tübingen to the eas ...
in 2003 at the age of 94 as a result of a
femoral neck fracture A hip fracture is a break that occurs in the upper part of the femur (thigh bone). Symptoms may include pain around the hip, particularly with movement, and shortening of the leg. Usually the person cannot walk. They most often occur as a res ...
.


The Budwig Diet

In 1952 she described a diet which she claimed had anti-cancer effects. She called it the “Budwig protocol”. The focus of this diet is on modifying the intake of dietary fats. It is a lacto-vegetarian diet rich in
flaxseed oil Linseed oil, also known as flaxseed oil or flax oil (in its edible form), is a colourless to yellowish oil obtained from the dried, ripened seeds of the flax plant (''Linum usitatissimum''). The oil is obtained by pressing, sometimes followed by ...
and other old-pressed vegetable oils, mixed with cottage cheese and meals high in fruits, vegetables with sauerkraut, freshly squeezed juices, nuts and seeds. The diet avoids animal fats, butter, margarine, meat, seafood and sugar. She recommended the consumption of garlic, leeks or onions as these plants contain proteins with sulphur content. Her dietary ideas inspired the research of
Catherine Kousmine Catherine Kousmine (September 17, 1904, in Hvalynsky, Russia – August 24, 1992, in Lutry, Switzerland) was a Russian physician who proposed an alternative cancer treatment. Kousmine devised a restrictive diet for treating many human ailments i ...
.Käsmayr, Anneli. (2017). ''Culinary Turn Aesthetic Practice of Cookery''. Transcript Verlag. p. 165. There is no reliable evidence supporting the claims of efficiency against cancer, or that this diet helps people with cancer in any meaningful way. There is no indication for using anti cancer diets and they can cause
adverse effects An adverse effect is an undesired harmful effect resulting from a medication or other intervention, such as surgery. An adverse effect may be termed a "side effect", when judged to be secondary to a main or therapeutic effect. The term complica ...
including
malnutrition Malnutrition occurs when an organism gets too few or too many nutrients, resulting in health problems. Specifically, it is "a deficiency, excess, or imbalance of energy, protein and other nutrients" which adversely affects the body's tissues a ...
,
stomach ache Abdominal pain, also known as a stomach ache, is a symptom associated with both non-serious and serious medical issues. Common causes of pain in the abdomen include gastroenteritis and irritable bowel syndrome. About 15% of people have a m ...
,
flatulence Flatulence, in humans, is the expulsion of gas from the intestines via the anus, commonly referred to as farting. "Flatus" is the medical word for gas generated in the stomach or bowels. A proportion of intestinal gas may be swallowed environm ...
, and
allergic reactions Allergies, also known as allergic diseases, refer a number of conditions caused by the hypersensitivity of the immune system to typically harmless substances in the environment. These diseases include hay fever, food allergies, atopic derma ...
. People with cancer who delay or forgo effective treatments as a result of using diets such as the Budwig Diet might suffer
relapse In internal medicine, relapse or recidivism is a recurrence of a past (typically medical) condition. For example, multiple sclerosis and malaria often exhibit peaks of activity and sometimes very long periods of dormancy, followed by relapse or r ...
, experience unnecessary disease progression, and experience continuing cancer-related symptoms.


Selected publications

*''Flax Oil as a True Aid against Arthritis, Heart Infarction and Cancer'' (1994) *''The Oil Protein Diet Cookbook'' (2006)


See also

*
List of unproven and disproven cancer treatments This is a non-exhaustive list of alternative treatments that have been promoted to treat or prevent cancer in humans but which lack scientific and medical evidence of effectiveness. In many cases, there is scientific evidence that the alleged tr ...
*
Quackery Quackery, often synonymous with health fraud, is the promotion of fraudulent or ignorant medical practices. A quack is a "fraudulent or ignorant pretender to medical skill" or "a person who pretends, professionally or publicly, to have skill, ...


References


External links


Works by Budwig in the Deutsche Nationalbibliothek
{{DEFAULTSORT:Budwig, Johanna 1908 births 2003 deaths 20th-century German inventors Alternative cancer treatment advocates Cancer researchers German biochemists German pharmacists German vegetarianism activists Pseudoscientific diet advocates German women biochemists Vegetarian cookbook writers Women inventors Writers from Essen