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Bubble CPAP is a non-invasive ventilation strategy for newborns with
infant respiratory distress syndrome Infantile respiratory distress syndrome (IRDS), also called respiratory distress syndrome of newborn, or increasingly surfactant deficiency disorder (SDD), and previously called hyaline membrane disease (HMD), is a syndrome in premature infants c ...
(IRDS). It is one of the methods by which
continuous positive airway pressure Continuous positive airway pressure (CPAP) is a form of positive airway pressure (PAP) ventilation in which a constant level of pressure greater than atmospheric pressure is continuously applied to the upper respiratory tract of a person. The ap ...
(CPAP) is delivered to a spontaneously breathing newborn to maintain lung volumes during expiration. With this method, blended and humidified
oxygen Oxygen is the chemical element with the symbol O and atomic number 8. It is a member of the chalcogen group in the periodic table, a highly reactive nonmetal, and an oxidizing agent that readily forms oxides with most elements as wel ...
is delivered via short binasal prongs or a nasal mask and pressure in the circuit is maintained by immersing the distal end of the expiratory tubing in water. The depth to which the tubing is immersed underwater determines the pressure generated in the airways of the infant. As the gas flows through the system, it "bubbles" out and prevents buildup of excess pressures. Bubble CPAP is appealing because of its simplicity and low cost. It is also associated with a decreased incidence of
bronchopulmonary dysplasia Bronchopulmonary dysplasia (BPD; part of the spectrum of chronic lung disease of infancy) is a chronic lung disease in which premature infants, usually those who were treated with supplemental oxygen, require long-term oxygen. The alveoli that are ...
(BPD) compared to
mechanical ventilation Mechanical ventilation, assisted ventilation or intermittent mandatory ventilation (IMV), is the medical term for using a machine called a ventilator to fully or partially provide artificial ventilation. Mechanical ventilation helps move air ...
. Not all infants with IRDS are candidates for initial treatment with CPAP and not all those who are given CPAP can be successfully managed with this modality.


History

In the early 1970s, Gregory et al. demonstrated that providing CPAP using an anesthesia bag improved oxygenation in preterm infants with respiratory distress syndrome. Subsequently, Jen-Tien Wung at Children's Hospital of New York,
Columbia University Columbia University (also known as Columbia, and officially as Columbia University in the City of New York) is a private research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhatt ...
developed the bubble CPAP system using short nasal prongs. In 1987 Avery et al. reported large differences in the risk-adjusted incidence of BPD in a comparison of 12 academic neonatal intensive care units in the United States. This study first identified the Columbia approach of using bubble CPAP in the delivery room as a possible strategy to reduce the incidence of BPD as compared to mechanical ventilation.


Components

The bubble CPAP system consists of three major components: 1. Gas source: An oxygen blender connected to a source of oxygen and compressed air is used to supply an appropriate concentration of inspired oxygen (
FiO2 Fraction of inspired oxygen (''FI''O2), corrected denoted with a capital "I", is the molar or volumetric fraction of oxygen in the inhaled gas. Medical patients experiencing difficulty breathing are provided with oxygen-enriched air, which means a ...
). The humidified blended oxygen is then circulated through corrugated tubing. 2. Pressure generator: Pressure in the bubble CPAP system is created by placing the distal expiratory tubing in water. Designated pressure is determined by the length of tubing immersed. 3. Patient interface: Nasal prongs are used as the nasal interface between the circuit and the infant's airway. Short and wide nasal prongs allow for a low resistance to air flow. It is important that the nasal interface be applied to the infant without air leakage while taking measures to prevent nasal trauma.


Nursing care

The successful application of bubble CPAP requires elaborate nursing care. There is a learning curve to the implementation of the bubble CPAP respiratory approach that requires a team effort. Respiratory therapists are important members of the team. # The system has to be snugly fitted and stationed on the infant's head. The nasal prongs can be secured by putting on an appropriate sized hat which rests on the lower part of the infant's ears and across the forehead. The tubing can be fastened with the help of safety pins and rubber bands. # Nasal prongs must be properly placed to prevent air leak. Application of a
Velcro Velcro, officially known as Velcro IP Holdings LLC and trading as Velcro Companies, is a British privately held company, founded by Swiss electrical engineer George de Mestral in the 1950s. It is the original manufacturer of hook-and-loop fasten ...
mustache placed over a piece of hydrocolloid dressing on the
philtrum The philtrum ( la, philtrum from Ancient Greek ''phíltron,'' lit. "love charm"), or medial cleft, is a vertical indentation in the middle area of the upper lip, common to therian mammals, extending in humans from the nasal septum to the tubercl ...
can prevent accidental incarceration of the prong on the nasal septum. # Gentle nasal suctioning is important to maintain clear airways. # Frequent decompression of the infant's stomach with an oro-gastric tube is necessary to promote comfort, and to prevent a distended stomach from splinting the diaphragm and compromising respiration.


References

{{Medicine Neonatology