Bryan Sykes
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Bryan Clifford Sykes (9 September 1947 – 10 December 2020) was a British geneticist and science writer who was a Fellow of Wolfson College and Emeritus Professor of
human genetics Human genetics is the study of inheritance as it occurs in human beings. Human genetics encompasses a variety of overlapping fields including: classical genetics, cytogenetics, molecular genetics, biochemical genetics, genomics, population gene ...
at the
University of Oxford , mottoeng = The Lord is my light , established = , endowment = £6.1 billion (including colleges) (2019) , budget = £2.145 billion (2019–20) , chancellor ...
.''Debrett's People of Today''
''Debrett's People of Today''. Retrieved 2 February 2016.
Sykes published the first report on retrieving DNA from ancient bone (''
Nature Nature, in the broadest sense, is the physics, physical world or universe. "Nature" can refer to the phenomenon, phenomena of the physical world, and also to life in general. The study of nature is a large, if not the only, part of science. ...
'', 1989). He was involved in a number of high-profile cases dealing with ancient DNA, including that of
Ötzi the Iceman Ötzi, also called the Iceman, is the natural mummy of a man who lived some time between 3350 and 3105 BC, discovered in September 1991 in the Ötztal Alps (hence the nickname "Ötzi") on the border between Austria and Italy. Ötzi is believed to ...
. He also suggested a Florida accountant by the name of Tom Robinson was a direct descendant of
Genghis Khan ''Chinggis Khaan'' ͡ʃʰiŋɡɪs xaːŋbr />Mongol script: ''Chinggis Qa(gh)an/ Chinggis Khagan'' , birth_name = Temüjin , successor = Tolui (as regent)Ögedei Khan , spouse = , issue = , house = Borjigin , ...
, a claim that was subsequently disproved. Sykes is best known outside the community of
geneticist A geneticist is a biologist or physician who studies genetics, the science of genes, heredity, and variation of organisms. A geneticist can be employed as a scientist or a lecturer. Geneticists may perform general research on genetic processe ...
s for his two popular books on the investigation of human history and prehistory through studies of
mitochondrial DNA Mitochondrial DNA (mtDNA or mDNA) is the DNA located in mitochondria, cellular organelles within eukaryotic cells that convert chemical energy from food into a form that cells can use, such as adenosine triphosphate (ATP). Mitochondrial D ...
.


Education

Sykes was educated at
Eltham College Eltham College is an independent day school situated in Mottingham, southeast London. Eltham and Mottingham once formed part of the same parish, hence its name. It is a member of The Headmasters' and Headmistresses' Conference (HMC). Early hi ...
, received his BSc from the
University of Liverpool , mottoeng = These days of peace foster learning , established = 1881 – University College Liverpool1884 – affiliated to the federal Victoria Universityhttp://www.legislation.gov.uk/ukla/2004/4 University of Manchester Act 200 ...
, his PhD from the
University of Bristol , mottoeng = earningpromotes one's innate power (from Horace, ''Ode 4.4'') , established = 1595 – Merchant Venturers School1876 – University College, Bristol1909 – received royal charter , type ...
, and his DSc from the
University of Oxford , mottoeng = The Lord is my light , established = , endowment = £6.1 billion (including colleges) (2019) , budget = £2.145 billion (2019–20) , chancellor ...
.


Career


''The Seven Daughters of Eve''

In 2001 (Banta Press Hardback) Sykes published a book for the popular audience, ''
The Seven Daughters of Eve ''The Seven Daughters of Eve'' is a 2001 semi-fictional book by Bryan Sykes that presents the science of human origin in Africa and their dispersion to a general audience. Sykes explains the principles of genetics and human evolution, the parti ...
'', in which he explained how the dynamics of maternal mitochondrial DNA (mtDNA) inheritance leave their mark on the human population in the form of genetic clans sharing common maternal descent. He notes that the majority of Europeans can be classified in seven such clans, known scientifically as
haplogroup A haplotype is a group of alleles in an organism that are inherited together from a single parent, and a haplogroup (haploid from the el, ἁπλοῦς, ''haploûs'', "onefold, simple" and en, group) is a group of similar haplotypes that share ...
s, distinguishable by differences in their mtDNA that are unique to each group, with each clan descending from a separate prehistoric female-line ancestor. He referred to these seven 'clan mothers' as 'daughters of Eve', a reference to the
mitochondrial Eve In human genetics, the Mitochondrial Eve (also ''mt-Eve, mt-MRCA'') is the matrilineal most recent common ancestor (MRCA) of all living humans. In other words, she is defined as the most recent woman from whom all living humans descend in an ...
to whom the mtDNA of all modern humans traces. Based on the geographical and ethnological distribution of the modern descendants of each clan he assigned provisional homelands for the seven clan mothers, and used the degree to which each clan diverges to approximate the time period when the clan mother would have lived. He then uses these deductions to give 'biographies' for each of the clan mothers, assigning them arbitrary names based on the scientific designation of their haplogroup (for example, using the name Xenia for the founder of haplogroup X).


''Blood of the Isles''

In his 2006 book ''Blood of the Isles'' (published in the United States and Canada as ''Saxons, Vikings and Celts: The Genetic Roots of Britain and Ireland''), Sykes examines British genetic "clans". He presents evidence from mitochondrial DNA, inherited by both sexes from their mothers, and the
Y chromosome The Y chromosome is one of two sex chromosomes (allosomes) in therian mammals, including humans, and many other animals. The other is the X chromosome. Y is normally the sex-determining chromosome in many species, since it is the presence or abse ...
, inherited by men from their fathers, and makes the following claims: * The genetic makeup of
Britain Britain most often refers to: * The United Kingdom, a sovereign state in Europe comprising the island of Great Britain, the north-eastern part of the island of Ireland and many smaller islands * Great Britain, the largest island in the United King ...
and Ireland is overwhelmingly what it has been since the
Neolithic The Neolithic period, or New Stone Age, is an Old World archaeological period and the final division of the Stone Age. It saw the Neolithic Revolution, a wide-ranging set of developments that appear to have arisen independently in several parts ...
period and to a very considerable extent since the
Mesolithic The Mesolithic (Greek: μέσος, ''mesos'' 'middle' + λίθος, ''lithos'' 'stone') or Middle Stone Age is the Old World archaeological period between the Upper Paleolithic and the Neolithic. The term Epipaleolithic is often used synonymous ...
period, especially in the female line, i.e. those people, who in time would become identified as British Celts (culturally speaking), but who (genetically speaking) should more properly be called
Cro-Magnon Early European modern humans (EEMH), or Cro-Magnons, were the first early modern humans (''Homo sapiens'') to settle in Europe, migrating from Western Asia, continuously occupying the continent possibly from as early as 56,800 years ago. They ...
. In continental Europe, this same Cro-Magnon genetic legacy gave rise to the
Basques The Basques ( or ; eu, euskaldunak ; es, vascos ; french: basques ) are a Southwestern European ethnic group, characterised by the Basque language, a common culture and shared genetic ancestry to the ancient Vascones and Aquitanians. Bas ...
. "Basque" and "Celt" are cultural designations, not genetic ones. * The contribution of the
Celts The Celts (, see pronunciation for different usages) or Celtic peoples () are. "CELTS location: Greater Europe time period: Second millennium B.C.E. to present ancestry: Celtic a collection of Indo-European peoples. "The Celts, an ancien ...
of Central Europe to the genetic makeup of Britain and Ireland was minimal; most of the genetic contribution to the
British Isles The British Isles are a group of islands in the North Atlantic Ocean off the north-western coast of continental Europe, consisting of the islands of Great Britain, Ireland, the Isle of Man, the Inner and Outer Hebrides, the Northern Isles, ...
of those we think of as Celtic, came from western continental Europe, i.e. the
Atlantic The Atlantic Ocean is the second-largest of the world's five oceans, with an area of about . It covers approximately 20% of Earth's surface and about 29% of its water surface area. It is known to separate the " Old World" of Africa, Europe an ...
seaboard. * The
Picts The Picts were a group of peoples who lived in what is now northern and eastern Scotland (north of the Firth of Forth) during Late Antiquity and the Early Middle Ages. Where they lived and what their culture was like can be inferred from ea ...
were not a separate people: the genetic makeup of the formerly Pictish areas of
Scotland Scotland (, ) is a country that is part of the United Kingdom. Covering the northern third of the island of Great Britain, mainland Scotland has a border with England to the southeast and is otherwise surrounded by the Atlantic Ocean to the ...
shows no significant differences from the general profile of the rest of Britain. The two "Pictland" regions are Tayside and Grampian. * The
Anglo-Saxons The Anglo-Saxons were a Cultural identity, cultural group who inhabited England in the Early Middle Ages. They traced their origins to settlers who came to Britain from mainland Europe in the 5th century. However, the ethnogenesis of the Anglo- ...
are supposed, by some, to have made a substantial contribution to the genetic makeup of England, but in Sykes's opinion it was under 20 percent of the total, even in
Southern England Southern England, or the South of England, also known as the South, is an area of England consisting of its southernmost part, with cultural, economic and political differences from the Midlands and the North. Officially, the area includes G ...
. * The
Vikings Vikings ; non, víkingr is the modern name given to seafaring people originally from Scandinavia (present-day Denmark, Norway and Sweden), who from the late 8th to the late 11th centuries raided, pirated, traded and se ...
(Danes and Norwegians) also made a substantial contribution, which is concentrated in central, northern and eastern England – the territories of the ancient
Danelaw The Danelaw (, also known as the Danelagh; ang, Dena lagu; da, Danelagen) was the part of England in which the laws of the Danes held sway and dominated those of the Anglo-Saxons. The Danelaw contrasts with the West Saxon law and the Mercian ...
. There is a very heavy Viking contribution in the
Orkney Orkney (; sco, Orkney; on, Orkneyjar; nrn, Orknøjar), also known as the Orkney Islands, is an archipelago in the Northern Isles of Scotland, situated off the north coast of the island of Great Britain. Orkney is 10 miles (16 km) north ...
and
Shetland Islands Shetland, also called the Shetland Islands and formerly Zetland, is a subarctic archipelago in Scotland lying between Orkney, the Faroe Islands and Norway. It is the northernmost region of the United Kingdom. The islands lie about to the no ...
, in the vicinity of 40 percent. Women as well as men contributed substantially in all these areas, showing that the Vikings engaged in large-scale settlement. * The
Norman Norman or Normans may refer to: Ethnic and cultural identity * The Normans, a people partly descended from Norse Vikings who settled in the territory of Normandy in France in the 10th and 11th centuries ** People or things connected with the Norm ...
contribution was extremely small, on the order of 2 percent. * There are only sparse traces of the Roman occupation, almost all in Southern England. * In spite of all these later contributions, the genetic makeup of the British Isles remains overwhelmingly what it was in the
Neolithic The Neolithic period, or New Stone Age, is an Old World archaeological period and the final division of the Stone Age. It saw the Neolithic Revolution, a wide-ranging set of developments that appear to have arisen independently in several parts ...
: a mixture of the first
Mesolithic The Mesolithic (Greek: μέσος, ''mesos'' 'middle' + λίθος, ''lithos'' 'stone') or Middle Stone Age is the Old World archaeological period between the Upper Paleolithic and the Neolithic. The term Epipaleolithic is often used synonymous ...
inhabitants with
Neolithic The Neolithic period, or New Stone Age, is an Old World archaeological period and the final division of the Stone Age. It saw the Neolithic Revolution, a wide-ranging set of developments that appear to have arisen independently in several parts ...
settlers who came by sea from
Iberia The Iberian Peninsula (), ** * Aragonese and Occitan: ''Peninsula Iberica'' ** ** * french: Péninsule Ibérique * mwl, Península Eibérica * eu, Iberiar penintsula also known as Iberia, is a peninsula in southwestern Europe, defi ...
and ultimately from the eastern
Mediterranean The Mediterranean Sea is a sea connected to the Atlantic Ocean, surrounded by the Mediterranean Basin and almost completely enclosed by land: on the north by Western and Southern Europe and Anatolia, on the south by North Africa, and on the e ...
. * There is a difference between the genetic histories of men and women in Britain and Ireland. The
matrilineage Matrilineality is the tracing of kinship through the female line. It may also correlate with a social system in which each person is identified with their matriline – their mother's lineage – and which can involve the inheritance o ...
s show a mixture of original Mesolithic inhabitants and later Neolithic arrivals from
Iberia The Iberian Peninsula (), ** * Aragonese and Occitan: ''Peninsula Iberica'' ** ** * french: Péninsule Ibérique * mwl, Península Eibérica * eu, Iberiar penintsula also known as Iberia, is a peninsula in southwestern Europe, defi ...
, whereas the
patrilineage Patrilineality, also known as the male line, the spear side or agnatic kinship, is a common kinship system in which an individual's family membership derives from and is recorded through their father's lineage. It generally involves the inheritan ...
s are much more strongly correlated with Iberia. * There is evidence for a "
Genghis Khan ''Chinggis Khaan'' ͡ʃʰiŋɡɪs xaːŋbr />Mongol script: ''Chinggis Qa(gh)an/ Chinggis Khagan'' , birth_name = Temüjin , successor = Tolui (as regent)Ögedei Khan , spouse = , issue = , house = Borjigin , ...
effect", whereby some male lineages in ancient times were much more successful than others in leaving large numbers of descendants; e.g.
Niall of the Nine Hostages Niall ''Noígíallach'' (; Old Irish "having nine hostages"), or Niall of the Nine Hostages, was a legendary, semi-historical Irish king who was the ancestor of the Uí Néill dynasties that dominated Ireland from the 6th to the 10th centuries. ...
in 4th and 5th century Ireland and
Somerled Somerled (died 1164), known in Middle Irish as Somairle, Somhairle, and Somhairlidh, and in Old Norse as Sumarliði , was a mid-12th-century Norse-Gaelic lord who, through marital alliance and military conquest, rose in prominence to create the ...
in 12th century Scotland. Sykes used a similar approach to that used in ''
The Seven Daughters of Eve ''The Seven Daughters of Eve'' is a 2001 semi-fictional book by Bryan Sykes that presents the science of human origin in Africa and their dispersion to a general audience. Sykes explains the principles of genetics and human evolution, the parti ...
'' to identify the nine "clan mothers" of Japanese ancestry, "all different from the seven European equivalents."


Modern evidence

With the advent of whole-genome sequencing and analysis of ancient DNA, many of Sykes' theories regarding the origins of the British have been largely invalidated. A 2018 study argues that over 90% of the DNA of the Neolithic population of Britain was overturned by a North European Bell Beaker population, originating from the Pontic Steppes, as part of an ongoing migration process that brought large amounts of Steppe DNA (including the R1b haplogroup) to North and West Europe. Modern autosomal genetic clustering is testament to this fact, as both modern and Iron Age British and Irish samples cluster genetically very closely with other North European populations, rather than Iberians, Galicians, Basques or those from the south of France. Similar studies have concluded that the Anglo-Saxons, while not replacing the previous populations outright, may have contributed more to the gene pool in much of England than Sykes had claimed.


Alleged hominid samples

Sykes and his team at
Oxford University Oxford () is a city in England. It is the county town and only city of Oxfordshire. In 2020, its population was estimated at 151,584. It is north-west of London, south-east of Birmingham and north-east of Bristol. The city is home to the ...
carried out DNA analysis of presumed
Yeti The Yeti ()"Yeti"
''Random House Webster's Unabridged Dictionary''.
is an ape-like creature purported t ...
samples and thinks the samples may have come from a hybrid species of bear produced from a mating between a
brown bear The brown bear (''Ursus arctos'') is a large bear species found across Eurasia and North America. In North America, the populations of brown bears are called grizzly bears, while the subspecies that inhabits the Kodiak Islands of Alaska is kno ...
and a
polar bear The polar bear (''Ursus maritimus'') is a hypercarnivorous bear whose native range lies largely within the Arctic Circle, encompassing the Arctic Ocean, its surrounding seas and surrounding land masses. It is the largest extant bear specie ...
. Sykes told
BBC News BBC News is an operational business division of the British Broadcasting Corporation (BBC) responsible for the gathering and broadcasting of news and current affairs in the UK and around the world. The department is the world's largest broadca ...
: He conducted another similar survey in 2014, this time examining samples attributed not just to yeti but also to
Bigfoot Bigfoot, also commonly referred to as Sasquatch, is a purported ape-like creature said to inhabit the forest of North America. Many dubious articles have been offered in attempts to prove the existence of Bigfoot, including anecdotal claims o ...
and other "anomalous primates." The study concluded that two of the 30 samples tested most closely resembled the genome of a
palaeolithic The Paleolithic or Palaeolithic (), also called the Old Stone Age (from Greek: παλαιός ''palaios'', "old" and λίθος ''lithos'', "stone"), is a period in human prehistory that is distinguished by the original development of stone too ...
polar bear, and that the other 28 were from living mammals. The samples were subsequently re-analysed by Ceiridwen Edwards and Ross Barnett. They concluded that the mutation that had led to the match with a polar bear was a damaged artefact, and suggested that the two hair samples were in fact from Himalayan brown bears (''U. arctos isabellinus''). These bears are known in Nepal as Dzu-the (a Nepalese term meaning cattle-bear), and have been associated with the myth of the yeti. Sykes and Melton acknowledged that their
GenBank The GenBank sequence database is an open access, annotated collection of all publicly available nucleotide sequences and their protein translations. It is produced and maintained by the National Center for Biotechnology Information (NCBI; a part ...
search was in error but suggested that the hairs were instead a match to a modern
polar bear The polar bear (''Ursus maritimus'') is a hypercarnivorous bear whose native range lies largely within the Arctic Circle, encompassing the Arctic Ocean, its surrounding seas and surrounding land masses. It is the largest extant bear specie ...
specimen "from the Diomede Islands in the Bering Sea reported in the same paper". They maintained that they did not see any sign of damage in their sequences and commented that they had "no reason to doubt the accuracy of these two sequences any more than the other 28 presented in the paper". Multiple further analyses, including replication of the single analysis conducted by Sykes and his team, were carried out in a study conducted by Eliécer E. Gutiérrez, a researcher at the
Smithsonian Institution The Smithsonian Institution ( ), or simply the Smithsonian, is a group of museums and education and research centers, the largest such complex in the world, created by the U.S. government "for the increase and diffusion of knowledge". Founded ...
and Ronald H. Pine, affiliated at the
University of Kansas The University of Kansas (KU) is a public research university with its main campus in Lawrence, Kansas, United States, and several satellite campuses, research and educational centers, medical centers, and classes across the state of Kansas. Tw ...
. All of these analyses found that the relevant genetic variation in brown bears makes it impossible to assign, with certainty, the Himalayan samples to either that species or to the polar bear. Because brown bears occur in the Himalayas, Gutiérrez and Pine stated that there is no reason to believe that the samples in question came from anything other than ordinary Himalayan brown bears.


Personal life

Sykes died on 10 December 2020.


Selected works

* * (see ''
The Seven Daughters of Eve ''The Seven Daughters of Eve'' is a 2001 semi-fictional book by Bryan Sykes that presents the science of human origin in Africa and their dispersion to a general audience. Sykes explains the principles of genetics and human evolution, the parti ...
'') * (see ''
Adam's Curse ''Adam's Curse: A Future Without Men'' (also known as ''Adam's Curse: A Story of Sex, Genetics, and the Extinction of Men'') is a 2003 book by Oxford University human genetics professor Bryan Sykes expounding his hypothesis that with the declinin ...
'') * * * *


Notes


External links


We're nearly all Celts under the skin
by Ian Johnston, ''
The Scotsman ''The Scotsman'' is a Scottish compact newspaper and daily news website headquartered in Edinburgh. First established as a radical political paper in 1817, it began daily publication in 1855 and remained a broadsheet until August 2004. Its par ...
''.
Celts descended from Spanish fishermen, study finds
''
The Independent ''The Independent'' is a British online newspaper. It was established in 1986 as a national morning printed paper. Nicknamed the ''Indy'', it began as a broadsheet and changed to tabloid format in 2003. The last printed edition was publis ...
'', 20 September 2006.
Oxford Ancestors website


''Telegraph'', 15 February 2008 {{DEFAULTSORT:Sykes, Bryan 1947 births 2020 deaths Recent African origin of modern humans English geneticists Genetic genealogists English science writers Fellows of Wolfson College, Oxford People educated at Eltham College English croquet players