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Bruce Spencer Weir (born 31 December 1943) is a New Zealand biostatistician and statistical geneticist. He is Professor of Biostatistics and Professor of Genome Sciences at the
University of Washington The University of Washington (UW, simply Washington, or informally U-Dub) is a public research university in Seattle, Washington. Founded in 1861, Washington is one of the oldest universities on the West Coast; it was established in Seattle a ...
. He was previously the
William Neal Reynolds William Neal Reynolds (March 22, 1863 – September 10, 1951) was a U.S. sportsman and businessman with R. J. Reynolds Tobacco Company, which was founded by his brother R. J. Reynolds. Early life Born in Patrick County, Virginia, Reynolds went ...
Professor of statistics and genetics and director of the Bioinformatics Research Center at
North Carolina State University North Carolina State University (NC State) is a public land-grant research university in Raleigh, North Carolina. Founded in 1887 and part of the University of North Carolina system, it is the largest university in the Carolinas. The universit ...
. He is known within academia for his research in
statistical Statistics (from German: ''Statistik'', "description of a state, a country") is the discipline that concerns the collection, organization, analysis, interpretation, and presentation of data. In applying statistics to a scientific, industria ...
and
forensic genetics DNA profiling (also called DNA fingerprinting) is the process of determining an individual's DNA characteristics. DNA analysis intended to identify a species, rather than an individual, is called DNA barcoding. DNA profiling is a forensic tec ...
, and outside academia for testifying in the
O.J. Simpson murder trial ''The People of the State of California v. Orenthal James Simpson'' was a criminal trial in Los Angeles County Superior Court starting in 1994, in which O. J. Simpson, a former National Football League (NFL) player, broadcaster and actor, was tr ...
in 1995.


Early life and education

Weir was born in Christchurch, New Zealand, the oldest child of Gordon and Peg Weir. He was a foundation pupil of
Shirley Boys' High School Shirley Boys' High School (known as SBHS) is a single sex state (public) secondary school in Christchurch, New Zealand. It was originally situated on a 6 hectare site in the suburb of Shirley, but in April 2019 moved, along with Avonside ...
. He went to the
University of Canterbury The University of Canterbury ( mi, Te Whare Wānanga o Waitaha; postnominal abbreviation ''Cantuar.'' or ''Cant.'' for ''Cantuariensis'', the Latin name for Canterbury) is a public research university based in Christchurch, New Zealand. It was ...
and was the first in his family to go to university. He gained his PhD in statistics at the
North Carolina State University North Carolina State University (NC State) is a public land-grant research university in Raleigh, North Carolina. Founded in 1887 and part of the University of North Carolina system, it is the largest university in the Carolinas. The universit ...
.


Testimony in O.J. Simpson murder case

During his testimony in the
O. J. Simpson murder case ''The People of the State of California v. Orenthal James Simpson'' was a criminal trial in Los Angeles County Superior Court starting in 1994, in which O. J. Simpson, a former National Football League (NFL) player, broadcaster and actor, was ...
, Weir was pressed by lawyer
Peter Neufeld Peter J. Neufeld (born July 17, 1950) is an American lawyer, cofounder, with Barry Scheck, of the Innocence Project, and a founding partner in the civil rights law firm Neufeld Scheck & Brustin. Starting from his earliest years as an attorney rep ...
on his failure to include a certain
genetic marker A genetic marker is a gene or DNA sequence with a known location on a chromosome that can be used to identify individuals or species. It can be described as a variation (which may arise due to mutation or alteration in the genomic loci) that can be ...
in his calculations of some of the DNA frequencies he had analyzed. In response, Weir acknowledged that he had in fact made a calculation error in failing to include this marker in all of his analyses of DNA samples in the case. Lawyers for the defense used this admission to attempt to undermine Weir's credibility, despite the fact that the error had little effect on the validity of the DNA evidence that had been presented. Weir subsequently recalculated his statistics and described his new findings in a subsequent day of testimony. Weir stated that after redoing his calculations, the odds that a blood mixture sample taken from the steering wheel of Simpson's
Ford Bronco The Ford Bronco is a model line of sport utility vehicles manufactured and marketed by Ford. The first SUV model developed by the company, five generations of the Bronco were sold from the 1966 to 1996 model years. A sixth generation of the mod ...
came from two unknown people increased from 1 in 59 to 1 in 26. Similarly, the equivalent odds for a blood mixture found on a glove outside Simpson's home were revised upward from 1 in 3,900 to 1 in 1,600. In his
redirect examination Redirect examination, in the United States, is the questioning of a witness who has already provided testimony under oath in response to direct examination as well as cross examination by the opponent. On redirect, the attorney offering the wi ...
that day, Weir asserted that the difference between his new and original results was not very
statistically significant In statistical hypothesis testing, a result has statistical significance when it is very unlikely to have occurred given the null hypothesis (simply by chance alone). More precisely, a study's defined significance level, denoted by \alpha, is the p ...
.


Honors and awards

Weir was a
Guggenheim Fellow Guggenheim Fellowships are grants that have been awarded annually since by the John Simon Guggenheim Memorial Foundation to those "who have demonstrated exceptional capacity for productive scholarship or exceptional creative ability in the ar ...
in 1983. He was named a fellow of the
American Association for the Advancement of Science The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific respons ...
in 1998 and of the
American Statistical Association The American Statistical Association (ASA) is the main professional organization for statisticians and related professionals in the United States. It was founded in Boston, Massachusetts on November 27, 1839, and is the second oldest continuousl ...
in 1999. He received the O. Max Gardner Award from the
University of North Carolina The University of North Carolina is the multi-campus public university system for the state of North Carolina. Overseeing the state's 16 public universities and the NC School of Science and Mathematics, it is commonly referred to as the UNC Sy ...
system in 2003. In 2019, he received the Elizabeth W. Jones Award for Excellence in Education from the
Genetics Society of America The Genetics Society of America (GSA) is a scholarly membership society of more than 5,500 genetics researchers and educators, established in 1931. The Society was formed from the reorganization of the Joint Genetics Sections of the American Soc ...
. In 2021 he was elected a Fellow of the
Royal Society The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, re ...
.


Personal life

Weir is married to Beth Weir, an academic with interests in
reading education Reading is the process of taking in the sense or meaning of letters, symbols, etc., especially by sight or touch. For educators and researchers, reading is a multifaceted process involving such areas as word recognition, orthography (spelling ...
. They have two children: Claudia Beth and Henry Bruce.


References


External links


Faculty page
* * {{DEFAULTSORT:Weir, Bruce Spencer Living people 1943 births New Zealand geneticists New Zealand statisticians New Zealand emigrants to the United States People from Christchurch Fellows of the American Association for the Advancement of Science Biostatisticians Statistical geneticists University of Washington faculty Fellows of the American Statistical Association University of Canterbury alumni North Carolina State University alumni North Carolina State University faculty Forensic scientists