Brigance is a surname. Notable people with the surname include:
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Albert Brigance (died 2007), author and special education resource specialist
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O. J. Brigance
Orenthial James Brigance (born September 29, 1969) is a former gridiron football, football linebacker who played in the Canadian Football League (CFL) and the National Football League (NFL). He is the senior advisor to player development for the B ...
(born 1969), American football player
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Tom Brigance (1913–1990), American fashion designer
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