Brian Wowk
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Brian G. Wowk, Ph.D. is a
medical physicist A medical physicist is a health professional with specialist education and training in the concepts and techniques of applying physics in medicine and competent to practice independently in one or more of the subfields (specialties) of medical phys ...
and cryobiologist known for the discovery and development of synthetic
molecules A molecule is a group of two or more atoms held together by attractive forces known as chemical bonds; depending on context, the term may or may not include ions which satisfy this criterion. In quantum physics, organic chemistry, and bioche ...
that mimic the activity of natural
antifreeze protein Antifreeze proteins (AFPs) or ice structuring proteins refer to a class of polypeptides produced by certain animals, plants, fungi and bacteria that permit their survival in temperatures below the freezing point of water. AFPs bind to small ...
s in
cryopreservation Cryo-preservation or cryo-conservation is a process where Organism, organisms, organelles, cell (biology), cells, Biological tissue, tissues, extracellular matrix, Organ (anatomy), organs, or any other biological constructs susceptible to damage ...
applications, sometimes called "ice blockers". As a senior scientist at 21st Century Medicine, Inc., he was a co-developer with
Greg Fahy Gregory M. Fahy is a California-based cryobiologist, biogerontologist, and businessman. He is Vice President and Chief Scientific Officer at Twenty-First Century Medicine, Inc, and has co-founded ''Intervene Immune'', a company developing clinical ...
of key technologies enabling
cryopreservation Cryo-preservation or cryo-conservation is a process where Organism, organisms, organelles, cell (biology), cells, Biological tissue, tissues, extracellular matrix, Organ (anatomy), organs, or any other biological constructs susceptible to damage ...
of large and complex tissues, including the first successful
vitrification Vitrification (from Latin ''vitreum'', "glass" via French ''vitrifier'') is the full or partial transformation of a substance into a glass, that is to say, a non-crystalline amorphous solid. Glasses differ from liquids structurally and glasses po ...
and transplantation of a
mammal Mammals () are a group of vertebrate animals constituting the class Mammalia (), characterized by the presence of mammary glands which in females produce milk for feeding (nursing) their young, a neocortex (a region of the brain), fur or ...
ian organ (
kidney The kidneys are two reddish-brown bean-shaped organs found in vertebrates. They are located on the left and right in the retroperitoneal space, and in adult humans are about in length. They receive blood from the paired renal arteries; blood ...
). Wowk is also known for early theoretical work on future applications of
molecular nanotechnology Molecular nanotechnology (MNT) is a technology based on the ability to build structures to complex, atomic specifications by means of mechanosynthesis. This is distinct from nanoscale materials. Based on Richard Feynman's vision of miniatur ...
, especially
cryonics Cryonics (from el, κρύος ''kryos'' meaning 'cold') is the low-temperature freezing (usually at ) and storage of human remains, with the speculative hope that resurrection may be possible in the future. Cryonics is regarded with skepticis ...
,
nanomedicine Nanomedicine is the medical application of nanotechnology. Nanomedicine ranges from the medical applications of nanomaterials and BioBrick, biological devices, to Nanoelectronics, nanoelectronic biosensors, and even possible future applicatio ...
, and
optics Optics is the branch of physics that studies the behaviour and properties of light, including its interactions with matter and the construction of instruments that use or detect it. Optics usually describes the behaviour of visible, ultraviole ...
. In the early 1990s he wrote that
nanotechnology Nanotechnology, also shortened to nanotech, is the use of matter on an atomic, molecular, and supramolecular scale for industrial purposes. The earliest, widespread description of nanotechnology referred to the particular technological goal o ...
would revolutionize optics, making possible
virtual reality Virtual reality (VR) is a simulated experience that employs pose tracking and 3D near-eye displays to give the user an immersive feel of a virtual world. Applications of virtual reality include entertainment (particularly video games), educ ...
display systems optically indistinguishable from real scenery as in the fictitious
Holodeck The Holodeck is a fictional device from the television franchise ''Star Trek'' which uses "holograms" (projected light and electromagnetic energy which create the illusion of solid objects) to create a realistic 3D simulation of a real or imag ...
of ''
Star Trek ''Star Trek'' is an American science fiction media franchise created by Gene Roddenberry, which began with the eponymous 1960s television series and quickly became a worldwide pop-culture phenomenon. The franchise has expanded into vari ...
''. These systems were described by Wowk in the chapter "Phased Array Optics" in the 1996 anthology ''Nanotechnology: Molecular Speculations on Global Abundance'' , and highlighted in the September 1998 ''Technology Watch'' section of
Popular Mechanics ''Popular Mechanics'' (sometimes PM or PopMech) is a magazine of popular science and technology, featuring automotive, home, outdoor, electronics, science, do-it-yourself, and technology topics. Military topics, aviation and transportation o ...
magazine.


Early life and education

He obtained his undergraduate and graduate degrees from the
University of Manitoba The University of Manitoba (U of M, UManitoba, or UM) is a Canadian public research university in the province of Manitoba.Winnipeg Winnipeg () is the capital and largest city of the province of Manitoba in Canada. It is centred on the confluence of the Red and Assiniboine rivers, near the longitudinal centre of North America. , Winnipeg had a city population of 749,6 ...
, Canada. Dr. Wowk obtained his PhD in physics in 1997. His graduate studies included work in online portal
imaging Imaging is the representation or reproduction of an object's form; especially a visual representation (i.e., the formation of an image). Imaging technology is the application of materials and methods to create, preserve, or duplicate images. ...
for
radiotherapy Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is a therapy using ionizing radiation, generally provided as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator. Radia ...
at the Manitoba Cancer Treatment and Research Foundation (now Cancer Care Manitoba), and work on artifact reduction for
functional magnetic resonance imaging Functional magnetic resonance imaging or functional MRI (fMRI) measures brain activity by detecting changes associated with blood flow. This technique relies on the fact that cerebral blood flow and neuronal activation are coupled. When an area o ...
at the
National Research Council of Canada The National Research Council Canada (NRC; french: Conseil national de recherches Canada) is the primary national agency of the Government of Canada dedicated to science and technology research & development. It is the largest federal research ...
. His work in the latter field is cited by several text books, including ''Functional MRI'' which includes an image he obtained of
magnetic field A magnetic field is a vector field that describes the magnetic influence on moving electric charges, electric currents, and magnetic materials. A moving charge in a magnetic field experiences a force perpendicular to its own velocity and to ...
changes inside the human body caused by
respiration Respiration may refer to: Biology * Cellular respiration, the process in which nutrients are converted into useful energy in a cell ** Anaerobic respiration, cellular respiration without oxygen ** Maintenance respiration, the amount of cellul ...
.


References


Notes

*
''Nanotechnology: Molecular Speculations on Global Abundance''
*
''Functional MRI''


External links


21st Century Medicine




{{DEFAULTSORT:Wowk, Brian Living people Cryobiology Cryonicists People from Winnipeg University of Manitoba alumni Year of birth missing (living people) Medical physicists