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Brian A. Kuhlman is an American professor of
biochemistry Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and ...
and biophysics at the
UNC School of Medicine The University of North Carolina School of Medicine is a professional school within the University of North Carolina at Chapel Hill. It offers a Doctor of Medicine degree along with combined Doctor of Medicine / Doctor of Philosophy or Doctor of M ...
of
University of North Carolina at Chapel Hill A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States ...
and a Sloan Research Fellow.


Early life

Kuhlman obtained Bachelor of Arts degree in chemical physics from
Rice University William Marsh Rice University (Rice University) is a Private university, private research university in Houston, Houston, Texas. It is on a 300-acre campus near the Houston Museum District and adjacent to the Texas Medical Center. Rice is ranke ...
in 1992. From 1993 to 1998 he studied under guidance of Daniel Raleigh to earn his Ph.D. in
chemistry Chemistry is the science, scientific study of the properties and behavior of matter. It is a natural science that covers the Chemical element, elements that make up matter to the chemical compound, compounds made of atoms, molecules and ions ...
from
Stony Brook University Stony Brook University (SBU), officially the State University of New York at Stony Brook, is a public research university in Stony Brook, New York. Along with the University at Buffalo, it is one of the State University of New York system's ...
and from 1999 to 2002 he studied under guidance from David Baker to obtain Damon Runyon Postdoctoral Fellowship at the
University of Washington The University of Washington (UW, simply Washington, or informally U-Dub) is a public research university in Seattle, Washington. Founded in 1861, Washington is one of the oldest universities on the West Coast; it was established in Seattle a ...
.


Career

In 2003, Kuhlman designed the first full-domain artificial protein,
Top7 Top7 is an artificial 93-residue protein, classified as a '' de novo'' protein since it was designed by Brian Kuhlman and Gautam Dantas in David Baker's laboratory at the University of Washington to have a unique fold not found in nature. The pr ...
, with Gautam Dantas and other researchers, in David Baker's laboratory. In his independent research laboratory, Kuhlman continued pioneering research in protein design, including breakthroughs in protein interface design, design of protein loops, stitching together components of natural proteins, designed fusions for bispecific antibodies, and progress toward vaccines.


Awards

*
DeLano Award for Computational Biosciences The DeLano Award for Computational Biosciences is a prize in the field of computational biology. It is awarded annually for "the most accessible and innovative development or application of computer technology to enhance research in the life scienc ...
*
Feynman Prize in Nanotechnology The Feynman Prize in Nanotechnology is an award given by the Foresight Institute for significant advances in nanotechnology. Two prizes are awarded annually, in the categories of experimental and theoretical work. There is also a separate challe ...
* Beckman Young Investigator


References


External links

* Living people American biochemists American biophysicists Rice University alumni Stony Brook University alumni University of Washington alumni Sloan Research Fellows University of North Carolina at Chapel Hill faculty Year of birth missing (living people) {{US-biochemist-stub