Branchpoint Binding Protein
   HOME

TheInfoList



OR:

Branchpoint Binding Protein (BBP) is an Orem RNA processing factor. The
protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
complex binds to the branchpoint sequence (BPS) in the pre-mRNA, aiding in
splice Splice may refer to: Connections * Rope splicing, joining two pieces of rope or cable by weaving the strands of each into the other ** Eye splice, a method of creating a permanent loop in the end of multi stranded rope by means of rope splicing * ...
site recognition. The role of the protein in
yeast Yeasts are eukaryotic, single-celled microorganisms classified as members of the fungus kingdom. The first yeast originated hundreds of millions of years ago, and at least 1,500 species are currently recognized. They are estimated to constitut ...
cells has been the subject of study, as for other
eukaryotic Eukaryotes () are organisms whose cells have a nucleus. All animals, plants, fungi, and many unicellular organisms, are Eukaryotes. They belong to the group of organisms Eukaryota or Eukarya, which is one of the three domains of life. Bacte ...
cells. The BPS that the protein binds to in yeast is UACUAAC.{{Cite journal, title = The Splicing Factor BBP Interacts Specifically with the Pre-mRNA Branchpoint Sequence UACUAAC, year=1997 , doi=10.1016/S0092-8674(00)80261-5 , last1=Berglund , first1=J.Andrew , last2=Chua , first2=Katrin , last3=Abovich , first3=Nadja , last4=Reed , first4=Robin , last5=Rosbash , first5=Michael , journal=Cell , volume=89 , issue=5 , pages=781–787 , pmid=9182766 , s2cid=10505875 , doi-access=free


References

Proteins RNA splicing