Bragg Curve
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The Bragg peak is a pronounced peak on the Bragg curve which plots the energy loss of ionizing radiation during its travel through matter. For protons, α-rays, and other ion rays, the peak occurs immediately before the particles come to rest. It is named after
William Henry Bragg Sir William Henry Bragg (2 July 1862 – 12 March 1942) was an English physicist, chemist, mathematician, and active sportsman who uniquelyThis is still a unique accomplishment, because no other parent-child combination has yet shared a Nobel ...
, who discovered it in 1903. When a fast
charged particle In physics, a charged particle is a particle with an electric charge. It may be an ion, such as a molecule or atom with a surplus or deficit of electrons relative to protons. It can also be an electron or a proton, or another elementary particle ...
moves through matter, it
ionizes Ionization, or Ionisation is the process by which an atom or a molecule acquires a negative or positive charge by gaining or losing electrons, often in conjunction with other chemical changes. The resulting electrically charged atom or molecule ...
atoms of the material and deposits a
dose Dose or Dosage may refer to: Music * ''Dose'' (Gov't Mule album), 1998 * ''Dose'' (Latin Playboys album) * ''Dosage'' (album), by the band Collective Soul * "Dose" (song), a 2018 song by Ciara * "Dose", song by Filter from the album '' Short ...
along its path. A peak occurs because the interaction
cross section Cross section may refer to: * Cross section (geometry) ** Cross-sectional views in architecture & engineering 3D *Cross section (geology) * Cross section (electronics) * Radar cross section, measure of detectability * Cross section (physics) **Ab ...
increases as the charged particle's energy decreases. Energy lost by charged particles is inversely proportional to the square of their velocity, which explains the peak occurring just before the particle comes to a complete stop. In the upper figure, it is the peak for alpha particles of 5.49 MeV moving through air. In the lower figure, it is the narrow peak of the "native" proton beam curve which is produced by a
particle accelerator A particle accelerator is a machine that uses electromagnetic fields to propel electric charge, charged particles to very high speeds and energies, and to contain them in well-defined particle beam, beams. Large accelerators are used for fun ...
of 250
MeV In physics, an electronvolt (symbol eV, also written electron-volt and electron volt) is the measure of an amount of kinetic energy gained by a single electron accelerating from rest through an electric potential difference of one volt in vacuum. ...
. The figure also shows the absorption of a beam of energetic
photon A photon () is an elementary particle that is a quantum of the electromagnetic field, including electromagnetic radiation such as light and radio waves, and the force carrier for the electromagnetic force. Photons are Massless particle, massless ...
s (
X-ray X-rays (or rarely, ''X-radiation'') are a form of high-energy electromagnetic radiation. In many languages, it is referred to as Röntgen radiation, after the German scientist Wilhelm Conrad Röntgen, who discovered it in 1895 and named it ' ...
s) which is entirely different in nature; the curve is mainly
exponential Exponential may refer to any of several mathematical topics related to exponentiation, including: *Exponential function, also: **Matrix exponential, the matrix analogue to the above *Exponential decay, decrease at a rate proportional to value * Exp ...
. This characteristic of proton beams was first recommended for use in cancer therapy by Robert R. Wilson in his 1946 article, Radiological Use of Fast Protons. Wilson studied how the depth of proton beam penetration could be controlled by the energy of the protons. This phenomenon is exploited in
particle therapy Particle therapy is a form of external beam radiotherapy using beams of energetic neutrons, protons, or other heavier positive ions for cancer treatment. The most common type of particle therapy as of August 2021 is proton therapy. In contrast ...
of cancer, specifically in proton therapy, to concentrate the effect of light
ion beam An ion beam is a type of charged particle beam consisting of ions. Ion beams have many uses in electronics manufacturing (principally ion implantation) and other industries. A variety of ion beam sources exists, some derived from the mercu ...
s on the
tumor A neoplasm () is a type of abnormal and excessive growth of tissue. The process that occurs to form or produce a neoplasm is called neoplasia. The growth of a neoplasm is uncoordinated with that of the normal surrounding tissue, and persists ...
being treated while minimizing the effect on the surrounding healthy tissue. The blue curve in the figure ("modified
proton beam * the species of particle, e.g. electrons, protons, or atomic nucleus, atomic nuclei * the mean energy of the particles, often expressed in electronvolts (typically keV to GeV) * the (average) particle current, often expressed in amperes * the part ...
") shows how the originally monoenergetic proton beam with the sharp peak is widened by increasing the range of energies, so that a larger tumor volume can be treated. The plateau created by modifying the proton beam is referred to as the spread out Bragg Peak, or SOBP, which allows the treatment to conform to not only larger tumors, but to more specific 3D shapes. This can be achieved by using variable thickness attenuators like spinning wedges.


See also

*
Stopping power (particle radiation) In nuclear and materials physics, stopping power is the retarding force acting on charged particles, typically alpha and beta particles, due to interaction with matter, resulting in loss of particle kinetic energy. Its application is important ...
*
Bremsstrahlung ''Bremsstrahlung'' (), from "to brake" and "radiation"; i.e., "braking radiation" or "deceleration radiation", is electromagnetic radiation produced by the deceleration of a charged particle when deflected by another charged particle, typicall ...
*
Linear energy transfer In dosimetry, linear energy transfer (LET) is the amount of energy that an ionizing particle transfers to the material traversed per unit distance. It describes the action of radiation into matter. It is identical to the retarding force acting o ...
*
Proton therapy In medicine, proton therapy, or proton radiotherapy, is a type of particle therapy that uses a beam of protons to irradiate diseased tissue, most often to treat cancer. The chief advantage of proton therapy over other types of external beam r ...


References


External links

* * * * * {{DEFAULTSORT:Bragg Peak Ionizing radiation Experimental particle physics Radiation therapy