John Robert (Bob) Spence (born February 10, 1946) is a former Major League Baseball player. Spence played for the Chicago White Sox from to . He batted left and threw right-handed. He was drafted by the White Sox in the 1st round (4th overall pick) of the 1967 amateur draft. He attended St. Augustine High School in San Diego, California and graduated in 1964. Following his retirement from baseball, he returned to St. Augustine as a teacher.

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1946 births Baseball players from San Diego Chicago White Sox players Lynchburg White Sox players Eugene Emeralds players Appleton Foxes players Tucson Toros players Living people {{US-baseball-first-baseman-stub