Blosozumab binds

SOST Sost or SOST may refer to: Places *Sost, Afghanistan, a village in Badakhshan Province *Sost, Pakistan, the last town inside Pakistan on the Karakoram Highway before the Chinese border * Sost, Hautes-Pyrénées, a commune in France Other uses ...

, a negative regulator of osteoblast activity. Blocking SOST activity can lead to increased bone density. Blosozaumab has been studied with regards to the treatment of osteoporosis in both men and postmenopausal women. Clinical trials with Blosozumab have shown the antibody to be well tolerated and effective in producing a bone anabolic effect. Blosozumab was developed by

Eli Lilly and Company Eli Lilly and Company is an American pharmaceutical company headquartered in Indianapolis, Indiana, with offices in 18 countries. Its products are sold in approximately 125 countries. The company was founded in 1876 by, and named after, Colonel ...

References

{{musculoskeletal-drug-stub Drugs developed by Eli Lilly and Company