Bloodborne Disease
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A blood-borne disease is a disease that can be spread through contamination by blood and other body fluids. Blood can contain pathogens of various types, chief among which are microorganisms, like bacteria and parasites, and non-living infectious agents such as viruses. Three blood-borne pathogens in particular, all viruses, are cited as of primary concern to health workers by the CDC-NIOSH: HIV, hepatitis B (HVB), &
hepatitis C Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver; it is a type of viral hepatitis. During the initial infection people often have mild or no symptoms. Occasionally a fever, dark urine, a ...
(HVC). Diseases that are not usually transmitted directly by blood contact, but rather by insect or other vector, are more usefully classified as vector-borne disease, even though the causative agent can be found in blood. Vector-borne diseases include West Nile virus, zika fever and malaria. Many blood-borne diseases can also be contracted by other means, including high-risk sexual behavior or intravenous drug use. These diseases have also been identified in sports medicine. Since it is difficult to determine what pathogens any given sample of blood contains, and some blood-borne diseases are lethal, standard medical practice regards all blood (and any body fluid) as potentially infectious. "Blood and body fluid precautions" are a type of infection control practice that seeks to minimize this sort of disease transmission.


Occupational exposure

Blood poses the greatest threat to health in a laboratory or clinical setting due to needlestick injuries (''e.g.'', lack of proper
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disposal techniques and/or
safety syringe A safety syringe is a syringe with a built-in safety mechanism to reduce the risk of needlestick injuries to healthcare workers and others. The needle on a safety syringe can be detachable or permanently attached. On some models, a sheath is pla ...
s). These risks are greatest among healthcare workers, including: nurses, surgeons, laboratory assistants, doctors,
phlebotomists Phlebotomy is the process of making a puncture in a vein, usually in the arm, with a cannula for the purpose of drawing blood. The procedure itself is known as a venipuncture, which is also used for intravenous therapy. A person who performs a ph ...
, and laboratory technicians.S. Deuffic-Burbana, E. Delarocque-Astagneauc, D. Abitebould, E. Bouvetd, Y. Yazdanpanah Blood-borne viruses in healthcare workers: Prevention and management. Journal of Clinical Virology 52(2011) 4–10 These roles often require the use of syringes for blood draws or to administer medications. The Occupational Safety and Health Administration (OSHA) prescribes 5 rules that are required for a healthcare facility to follow in order to reduce the risk of employee exposure to blood-borne pathogens. They are: * Written exposure control plan * Engineering controls (Sharps containers, detachable and retractable needles, syringe caps, etc.) * Safe work practices and safety devices * Hepatitis B vaccine available to employees * Education and post-exposure follow up These controls, while general, serve to greatly reduce the incidence of blood-borne disease transmission in occupational settings of healthcare workers. There are 26 different viruses that have been shown to present in healthcare workers as a result of occupational exposure. The most common blood-borne diseases are hepatitis B (HBV),
hepatitis C Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver; it is a type of viral hepatitis. During the initial infection people often have mild or no symptoms. Occasionally a fever, dark urine, a ...
(HCV), and human immunodeficiency virus (HIV).Annette Prüss-Üstün, Elisabetta Rapiti, and Yvan Hutin Estimation of the Global Burden of Disease Attributable to Contaminated Sharps Injuries Among Health-Care Workers. American Journal of Industrial Medicine 48:482–490 (2005) Exposure is possible through blood of an infected patient splashing onto mucous membranes; however, the greatest exposure risk was shown to occur during percutaneous injections performed for vascular access. These include blood draws, as well as catheter placement, as both typically use hollow bore needles. Preventive measures for occupational exposure include standard precautions (hand washing, sharp disposal containers), as well as additional education. Advancements in the design of safety engineered devices have played a significant role in decreasing rates of occupational exposure to blood-borne disease. According to the Massachusetts Sharps Injury Surveillance System, needle devices without safety features accounted for 53% of the 2010 reported sharps injuries. Safer sharps devices now have engineering controls, such as a protective shield over the needle, and sharps containers that have helped to decrease this statistic. These safer alternatives are highly effective in substantially reducing injuries. For instance, almost 83% of injuries from hollow bore needles can be prevented with the use of safer sharps devices.


Blood transfusions

Blood for blood transfusion is screened for many blood-borne diseases. Additionally, a technique that uses a combination of riboflavin and UV light to inhibit the replication of these pathogens by altering their
nucleic acid Nucleic acids are biopolymers, macromolecules, essential to all known forms of life. They are composed of nucleotides, which are the monomers made of three components: a 5-carbon sugar, a phosphate group and a nitrogenous base. The two main cl ...
s can be used to treat blood components prior to their transfusion, and can reduce the risk of disease transmission. A technology using the synthetic psoralen (amotosalen HCl) and
UVA UVA most often refers to: * Ultraviolet A, a type of ultraviolet radiation * University of Virginia, a public research university in Charlottesville, Virginia, United States Uva or UVA may also refer to: Places * Uva, Missouri, an unincorpora ...
light (320–400 nm) has been implemented in European blood centers for the treatment of platelet and plasma components to prevent transmission of blood-borne diseases caused by bacteria, viruses and protozoa.


Needle exchange programs

Needle exchange program A needle and syringe programme (NSP), also known as needle exchange program (NEP), is a social service that allows injecting drug users (IDUs) to obtain clean and unused hypodermic needles and associated paraphernalia at little or no cost. It ...
s (NEPs) are an attempt to reduce the spread of blood-borne diseases between intravenous drug users. They often also provide addiction counseling services, infectious disease testing, and in some cases mental health care and other case management. NEPs acquired their name as they were initially places where intravenous (IV) illicit substance users were provided with clean, unused needles in exchange for their used needles. This allows for proper disposal of the needles. Empirical studies confirm the benefits of NEPs. NEPs can affect behaviors that result in the transmission of HIV. These behaviors include decreased sharing of used syringes, which reduces contaminated syringes from circulation and replaces them with sterile ones, among other risk reductions.


Prevention

Follow standard precautions to help prevent the spread of blood-borne pathogens and other diseases whenever there is a risk of exposure to blood or other bodily fluids. Standard precautions include maintaining personal hygiene and using personal protective equipment (PPE), engineering controls, and work practice controls among others. Always avoid contact with blood and other bodily fluids. Wear disposable gloves when providing care, particularly if you may come into contact with blood or bodily fluids. Dispose of gloves properly and change gloves when providing care to a new patient. Use needles with safety devices to help prevent needlestick injury and exposure to blood-borne pathogens. A hierarchy of controls can help to prevent environmental and occupational exposures and subsequent diseases. These include: * Elimination: Physically remove hazards, including needles that lack a safety device. Additionally, eliminate the use of needle devices whenever safe and effective alternatives are available. * Substitution: Replace needles without safety devices with ones that have a safety feature built in. This has been shown to reduce blood-borne diseases transmitted via needlestick injuries. * Engineering controls: Isolate people from the hazard by providing sharps containers for workers to immediately place needles in after use, which means putting them within arm's reach of wherever patient treatment occurs, such as in every physician's exam room, every draw station in a medical lab, and every bedside in a hospital ward or wing. * Administrative controls: Change the way people work by creating a culture of safety such as avoiding recapping or bending needles that may be contaminated and promptly disposing of used needle devices and other sharps. Personal protective equipment: Protect workers with PPE such as gloves and masks to avoid transmission of blood and other bodily fluids.


See also

* BTSB anti-D scandal * Contaminated haemophilia blood products *
Contaminated blood scandal in the United Kingdom In the 1970s and 1980s, a large number of people – most of whom had haemophilia – were infected with hepatitis C and HIV, the virus that leads to acquired immune deficiency syndrome (AIDS), as a result of receiving contaminated clotting f ...
*
Hematology Hematology ( always spelled haematology in British English) is the branch of medicine concerned with the study of the cause, prognosis, treatment, and prevention of diseases related to blood. It involves treating diseases that affect the produc ...
*
HIV-tainted blood scandal (Japan) In the 1980s, between one and two thousand haemophilia patients in Japan contracted HIV via contaminated blood products. Controversy centered on the continued use of non-heat-treated blood products after the development of heat treatments that pr ...
*
Infected blood scandal (France) In April 1991, the doctor and journalist published an article in the French weekly magazine the ' showing that the ' knowingly distributed blood products contaminated with HIV to haemophiliacs in 1984 and 1985, leading to an outbreak of HIV/AID ...
*
Plasma Economy Plasma Economy () was a 1991–1995 plasmapheresis campaign by the Henan provincial government in China, in which blood plasma was extracted in exchange for money. The campaign attracted 3 million donors, most of whom lived in rural China, and i ...
* Royal Commission of Inquiry on the Blood System in Canada


References


External links


Selected EPA-registered Disinfectants—U.S. Environmental Protection Agency

OSHA Bloodborne Pathogen Standard (BBPS)

Bloodborne Pathogens and Needlestick Prevention
from the Occupational Safety and Health Administration (OSHA)
OSHA Bloodborne Pathogens Workplace Safety Standards and Regulations

OSHA Bloodborne Pathogens Training


* ttp://www.vega.org.uk/video/programme/87 Professor Andrew Speilman, Entomologist, Harvard School of Hygiene and Public HealthFreeview Malaria video by the
Vega Science Trust The Vega Science Trust was a not-for-profit organisation which provided a platform from which scientists can communicate directly with the public on science by using moving image, sound and other related means. The Trust closed in 2012 but the web ...
.
Rob Hutchinson, Entomolgoist, Mosquitoes
London School of Hygiene and Tropical Diseases. Freeview video by the Vega Science Trust. *
NIOSH Bloodborne Infectious Diseases Topic Page
{{Concepts in infectious disease Infectious diseases Occupational diseases