Blast2GO, first published in 2005, is a

bioinformatics Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combi ...

software tool for the automatic, high-throughput functional annotation of novel sequence data (

gene In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...

protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...

s). It makes use of the

BLAST Blast or The Blast may refer to: *Explosion, a rapid increase in volume and release of energy in an extreme manner *Detonation, an exothermic front accelerating through a medium that eventually drives a shock front Film * ''Blast'' (1997 film), ...

algorithm to identify similar sequences to then transfers existing functional annotation from yet characterised sequences to the novel one. The functional information is represented via the

Gene Ontology The Gene Ontology (GO) is a major bioinformatics initiative to unify the representation of gene and gene product attributes across all species. More specifically, the project aims to: 1) maintain and develop its controlled vocabulary of gene and g ...

(GO), a controlled vocabulary of functional attributes. The Gene Ontology, or GO, is a major

initiative to unify the representation of

and

gene product A gene product is the biochemical material, either RNA or protein, resulting from expression of a gene. A measurement of the amount of gene product is sometimes used to infer how active a gene is. Abnormal amounts of gene product can be correlated ...

attributes across all

species In biology, a species is the basic unit of classification and a taxonomic rank of an organism, as well as a unit of biodiversity. A species is often defined as the largest group of organisms in which any two individuals of the appropriate s ...

References

External links

* Blast2GO - Tool for functional annotation of (novel) sequences and the analysis of annotation data.
Company developing Blast2GO
— BioBam Bioinformatics S.L., a bioinformatics company dedicated to creating user-friendly software for the scientific community is developing, maintaining and distributing Blast2GO.
Gene Ontology Tools
— Provides access to the ontologies, software tools, annotated gene product lists, and reference documents describing the GO and its uses.
PlantRegMap
��Plant GO annotation for 165 species and GO enrichment analysis Bioinformatics algorithms Bioinformatics software Laboratory software Public-domain software Genomics {{bioinformatics-stub

See also

References

External links