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Biosecurity refers to measures aimed at preventing the introduction and/or spread of harmful
organism In biology, an organism () is any living system that functions as an individual entity. All organisms are composed of cells (cell theory). Organisms are classified by taxonomy into groups such as multicellular animals, plants, and ...
s (e.g.
virus A virus is a submicroscopic infectious agent that replicates only inside the living cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Since Dmitri Ivanovsk ...
es,
bacteria Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of prokaryotic microorganisms. Typically a few micrometr ...
, etc.) to
animal Animals are multicellular, eukaryotic organisms in the Kingdom (biology), biological kingdom Animalia. With few exceptions, animals Heterotroph, consume organic material, Cellular respiration#Aerobic respiration, breathe oxygen, are Motilit ...
s and
plant Plants are predominantly photosynthetic eukaryotes of the kingdom Plantae. Historically, the plant kingdom encompassed all living things that were not animals, and included algae and fungi; however, all current definitions of Plantae exclu ...
s in order to minimize the risk of transmission of
infectious disease An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable di ...
. In
agriculture Agriculture or farming is the practice of cultivating plants and livestock. Agriculture was the key development in the rise of sedentary human civilization, whereby farming of domesticated species created food surpluses that enabled people t ...
, these measures are aimed at protecting food crops and
livestock Livestock are the domesticated animals raised in an agricultural setting to provide labor and produce diversified products for consumption such as meat, eggs, milk, fur, leather, and wool. The term is sometimes used to refer solely to animal ...
from pests, invasive species, and other organisms not conducive to the welfare of the human population. The term includes biological threats to people, including those from pandemic diseases and
bioterrorism Bioterrorism is terrorism involving the intentional release or dissemination of biological agents. These agents are bacteria, viruses, insects, fungi, and/or toxins, and may be in a naturally occurring or a human-modified form, in much the same ...
. The definition has sometimes been broadened to embrace other concepts, and it is used for different purposes in different contexts. The
COVID-19 pandemic The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identif ...
is a recent example of a threat for which biosecurity measures have been needed in all countries of the world.


Background and terminology

The term "biosecurity" has been defined differently by various disciplines. The term was first used by the
agricultural Agriculture or farming is the practice of cultivating Plant, plants and livestock. Agriculture was the key development in the rise of Sedentism, sedentary human civilization, whereby farming of Domestication, domesticated species created food ...
and
environmental A biophysical environment is a biotic and abiotic surrounding of an organism or population, and consequently includes the factors that have an influence in their survival, development, and evolution. A biophysical environment can vary in scale f ...
communities to describe preventative measures against threats from naturally occurring diseases and pests, later expanded to
introduced species An introduced species, alien species, exotic species, adventive species, immigrant species, foreign species, non-indigenous species, or non-native species is a species living outside its native distributional range, but which has arrived there ...
. Australia and New Zealand, among other countries, had incorporated this definition within their legislation by 2010.Full text
/ref> New Zealand was the earliest adopter of a comprehensive approach with its
Biosecurity Act 1993 Biosecurity Act 1993 is an Act of Parliament in New Zealand. The Act is a restatement and reform of the laws relating to pests and other unwanted organisms. It was a world first. In the Act an "unwanted organism" is defined to be one that "is ...
. In 2001, the US
National Association of State Departments of Agriculture The National Association of State Department of Agriculture (NASDA) is an American organization of state departments of agriculture. Founded in 1915, NASDA's mission is to represent the state departments of agriculture in the development, implement ...
(NASDA) defined biosecurity as "the sum of risk management practices in defense against biological threats", and its main goal as "protect ngagainst the risk posed by disease and organisms". In 2010, the
World Health Organization The World Health Organization (WHO) is a specialized agency of the United Nations responsible for international public health. The WHO Constitution states its main objective as "the attainment by all peoples of the highest possible level of h ...
(WHO) provided an information note describing biosecurity as a strategic and integrated approach to analysing and managing relevant risks to human, animal and plant life and health and associated risks for the environment. In another document, it describes the aim of biosecurity being "to enhance the ability to protect
human health Health, according to the World Health Organization, is "a state of complete physical, mental and social well-being and not merely the absence of disease and infirmity".World Health Organization. (2006)''Constitution of the World Health Organiza ...
, agricultural production systems, and the people and industries that depend on them", with the overarching goal being "to prevent, control and/or manage risks to life and health as appropriate to the particular biosecurity sector". Measures taken to counter biosecurity risks typically include compulsory terms of
quarantine A quarantine is a restriction on the movement of people, animals and goods which is intended to prevent the spread of disease or pests. It is often used in connection to disease and illness, preventing the movement of those who may have been ...
, and are put in place to minimise the risk of invasive pests or
disease A disease is a particular abnormal condition that negatively affects the structure or function of all or part of an organism, and that is not immediately due to any external injury. Diseases are often known to be medical conditions that a ...
s arriving at a specific location that could damage crops and
livestock Livestock are the domesticated animals raised in an agricultural setting to provide labor and produce diversified products for consumption such as meat, eggs, milk, fur, leather, and wool. The term is sometimes used to refer solely to animal ...
as well as the wider environment. In general, the term is today taken to include managing biological threats to people, industries or environment. These may be from foreign or
endemic Endemism is the state of a species being found in a single defined geographic location, such as an island, state, nation, country or other defined zone; organisms that are indigenous to a place are not endemic to it if they are also found elsew ...
organisms, but they can also extend to pandemic diseases and the threat of
bioterrorism Bioterrorism is terrorism involving the intentional release or dissemination of biological agents. These agents are bacteria, viruses, insects, fungi, and/or toxins, and may be in a naturally occurring or a human-modified form, in much the same ...
, both of which pose threats to
public health Public health is "the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals". Analyzing the det ...
.


Laboratory biosafety and intentional harm

The definition has sometimes been broadened to embrace other concepts, and it is used for different purposes in different contexts. A 2016 draft handbook on biosecurity education produced by the Bradford Disarmament Research Centre at
Bradford University The University of Bradford is a public research university located in the city of Bradford, West Yorkshire, England. A plate glass university, it received its royal charter in 1966, making it the 40th university to be created in Britain, but ...
in the UK, where the focus is on the dangers of "dual-use" research, defines the term as meaning "successful minimising of the risks that the biological sciences will be deliberately or accidentally misused in a way which causes harm for humans, animals, plants or the environment, including through awareness and understanding of the risks". From the late 1990s, in response to the threat of
biological terrorism Bioterrorism is terrorism involving the intentional release or dissemination of biological agents. These agents are bacteria, viruses, insects, fungi, and/or toxins, and may be in a naturally occurring or a human-modified form, in much the same ...
, the term started to include the prevention of the theft of biological materials from
research laboratories A research institute, research centre, research center or research organization, is an establishment founded for doing research. Research institutes may specialize in basic research or may be oriented to applied research. Although the term often i ...
, called "laboratory biosecurity" by WHO. The term
laboratory biosafety One use of the concept of biocontainment is related to laboratory biosafety and pertains to microbiology laboratories in which the physical containment of pathogenic organisms or agents (bacteria, viruses, and toxins) is required, usually by is ...
refers to the measures taken "to reduce the risk of accidental release of or exposure to infectious disease agents", whereas laboratory biosecurity is usually taken to mean "a set of systems and practices employed in legitimate bioscience facilities to reduce the risk that dangerous biological agents will be stolen and used maliciously". Joseph Kanabrocki (2017) source elaborates: "Biosafety focuses on protection of the researcher, their contacts and the environment via accidental release of a pathogen from containment, whether by direct release into the environment or by a laboratory-acquired infection. Conversely, biosecurity focuses on controlling access to pathogens of consequence and on the reliability of the scientists granted this access (thereby reducing the threat of an intentional release of a pathogen) and/or access to sensitive information related to a pathogen's virulence, host-range, transmissibility, resistance to medical countermeasures, and environmental stability, among other things". In the US, the National Science Advisory Board on Biosecurity was created in 2004 to provide biosecurity oversight of " dual-use research", defined as "biological research with legitimate scientific purpose that may be misused to pose a biological threat to
public health Public health is "the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals". Analyzing the det ...
and/or
national security National security, or national defence, is the security and defence of a sovereign state, including its citizens, economy, and institutions, which is regarded as a duty of government. Originally conceived as protection against military atta ...
". In 2006, the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
defined biosecurity as "security against the inadvertent, inappropriate, or intentional malicious or malevolent use of potentially dangerous biological agents or
biotechnology Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used b ...
, including the development, production, stockpiling, or use of biological weapons as well as outbreaks of newly emergent and epidemic disease". A number of nations have developed
biological weapons A biological agent (also called bio-agent, biological threat agent, biological warfare agent, biological weapon, or bioweapon) is a bacterium, virus, protozoan, parasite, fungus, or toxin that can be used purposefully as a weapon in bioterrorism ...
for military use, and many civilian research projects in medicine have the potential to be used in military applications (dual-use research), so biosecurity
protocol Protocol may refer to: Sociology and politics * Protocol (politics), a formal agreement between nation states * Protocol (diplomacy), the etiquette of diplomacy and affairs of state * Etiquette, a code of personal behavior Science and technolog ...
s are used to prevent dangerous biological materials from falling into the hands of malevolent parties.


Laboratory program

Components of a laboratory biosecurity program include: *
Physical security Physical security describes security measures that are designed to deny unauthorized access to facilities, equipment and resources and to protect personnel and property from damage or harm (such as espionage, theft, or terrorist attacks). Physica ...
* Personnel security * Material control and
accountability Accountability, in terms of ethics and governance, is equated with answerability, blameworthiness, liability, and the expectation of account-giving. As in an aspect of governance, it has been central to discussions related to problems in the publ ...
* Transport security *
Information security Information security, sometimes shortened to InfoSec, is the practice of protecting information by mitigating information risks. It is part of information risk management. It typically involves preventing or reducing the probability of unauthorize ...
* Program management * Biological Security


Animals and plants

Threats to animals and plants, in particular food crops, which may in turn threaten human health, are typically overseen by a government department of agriculture. Animal biosecurity encompasses different means of prevention and containment of disease agents in a specific area. A critical element in animal biosecurity is biocontainment – the control of disease agents already present in a particular area and work to prevent transmission.1. Thomson, J. Biosecurity: preventing and controlling diseases in the beef herd. Livestock Conservation Institute; 1991; 49-51. Animal biosecurity may protect organisms from infectious agents or noninfectious agents such as toxins or pollutants, and can be executed in areas as large as a nation or as small as a local farm. Animal biosecurity takes into account the
epidemiological Epidemiology is the study and analysis of the distribution (who, when, and where), patterns and determinants of health and disease conditions in a defined population. It is a cornerstone of public health, and shapes policy decisions and evidenc ...
triad for disease occurrence: the individual host, the disease, and the environment in contributing to disease susceptibility. It aims to improve nonspecific immunity of the host to resist the introduction of an agent, or limit the risk that an agent will be sustained in an environment at adequate levels. Biocontainment works to improve specific immunity towards already present pathogens. The
aquaculture Aquaculture (less commonly spelled aquiculture), also known as aquafarming, is the controlled cultivation ("farming") of aquatic organisms such as fish, crustaceans, mollusks, algae and other organisms of value such as aquatic plants (e.g. lot ...
industry is also vulnerable to pathogenic organisms, including
fungal A fungus ( : fungi or funguses) is any member of the group of eukaryotic organisms that includes microorganisms such as yeasts and molds, as well as the more familiar mushrooms. These organisms are classified as a kingdom, separately from th ...
, bacterial, or viral infections which can affect fish at different stages of their life cycle.


Human health

Direct threats to human health may come in the form of
epidemic An epidemic (from Ancient Greek, Greek ἐπί ''epi'' "upon or above" and δῆμος ''demos'' "people") is the rapid spread of disease to a large number of patients among a given population within an area in a short period of time. Epidemics ...
s or pandemics, such as the 1918
Spanish flu The 1918–1920 influenza pandemic, commonly known by the misnomer Spanish flu or as the Great Influenza epidemic, was an exceptionally deadly global influenza pandemic caused by the H1N1 influenza A virus. The earliest documented case was ...
pandemic and other
influenza Influenza, commonly known as "the flu", is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These symptoms ...
epidemics,
MERS Middle East respiratory syndrome (MERS) is a viral respiratory infection caused by ''Middle East respiratory syndrome–related coronavirus'' (MERS-CoV). Symptoms may range from none, to mild, to severe. Typical symptoms include fever, cough, ...
,
SARS Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by the severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), the first identified strain of the SARS coronavirus species, ''sever ...
, or the
COVID-19 pandemic The COVID-19 pandemic, also known as the coronavirus pandemic, is an ongoing global pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The novel virus was first identif ...
, or they may be deliberate attacks (bioterrorism). The country/federal and/or state
health department A health department or health ministry is a part of government which focuses on issues related to the general health of the citizenry. Subnational entities, such as states, counties and cities, often also operate a health department of their ow ...
s are usually responsible for managing the control of outbreaks and transmission and the supply of information to the public.


Medical countermeasures

Medical countermeasures (MCMs) are products such as
biologics A biopharmaceutical, also known as a biological medical product, or biologic, is any pharmaceutical drug product manufactured in, extracted from, or semisynthesized from biological sources. Different from totally synthesized pharmaceuticals, th ...
and
pharmaceutical drug A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy (pharmacotherapy) is an important part of the medical field and re ...
s that can protect from or treat the effects of a chemical, biological, radiological, or nuclear (CBRN) attack or in the case of public health emergencies. MCMs can also be used for prevention and diagnosis of symptoms associated with CBRN attacks or threats. In the US, the
Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is respon ...
(FDA) runs a program called the "FDA Medical Countermeasures Initiative" (MCMi), with programs funded by the
federal government A federation (also known as a federal state) is a political entity characterized by a union of partially self-governing provinces, states, or other regions under a central federal government (federalism). In a federation, the self-governin ...
. It helps support "partner" agencies and organisations prepare for public health emergencies that could require MCMs.


International agreements and guidelines


Agricultural biosecurity and human health

Various international organisations, international bodies and legal instruments and agreements make up a worldwide governance framework for biosecurity. Standard-setting organisations include the
Codex Alimentarius Commission The Codex Alimentarius () is a collection of internationally recognized standards, codes of practice, guidelines, and other recommendations published by the Food and Agriculture Organization of the United Nations relating to food, food production ...
(CAC), the
World Organisation for Animal Health The World Organisation for Animal Health (WOAH), formerly the (OIE), is an intergovernmental organization coordinating, supporting and promoting animal disease control. Mission and status The main objective of the WOAH is to control epizo ...
(OIE) and the
Commission on Phytosanitary Measures Commission or commissioning may refer to: Business and contracting * Commission (remuneration), a form of payment to an agent for services rendered ** Commission (art), the purchase or the creation of a piece of art most often on behalf of anothe ...
(CPM) develop standards pertinent to their focuses, which then become international reference points through the
World Trade Organization The World Trade Organization (WTO) is an intergovernmental organization that regulates and facilitates international trade. With effective cooperation in the United Nations System, governments use the organization to establish, revise, and e ...
(WTO)'s Agreement on the Application of Sanitary and Phytosanitary Measures (SPS Agreement), created in 1995. This agreement requires all members of the WTO to consider all import requests concerning agricultural products from other countries. Broadly, the measures covered by the agreement are those aimed at the protection of human, animal or plant life or health from certain risks. Other important global and regional agreements include the
International Health Regulations The International Health Regulations (IHR), first adopted by the World Health Assembly in 1969 and last revised in 2005, are a legally binding rules that only apply to the WHO that is an instrument that aims for international collaboration "to pre ...
(IHR, 2005), the
International Plant Protection Convention The International Plant Protection Convention (IPPC) is a 1951 multilateral treaty overseen by the United Nations Food and Agriculture Organization that aims to secure coordinated, effective action to prevent and to control the introduction and ...
(IPPC), the
Cartagena Protocol on Biosafety The Cartagena Protocol on Biosafety to the Convention on Biological Diversity is an international agreement on biosafety as a supplement to the Convention on Biological Diversity (CBD) effective since 2003. The Biosafety Protocol seeks to prote ...
, the
Codex Alimentarius The Codex Alimentarius () is a collection of internationally recognized standards, codes of practice, guidelines, and other recommendations published by the Food and Agriculture Organization of the United Nations relating to food, food production ...
, the
Convention on Biological Diversity The Convention on Biological Diversity (CBD), known informally as the Biodiversity Convention, is a multilateral treaty. The Convention has three main goals: the conservation of biological diversity (or biodiversity); the sustainable use of its ...
(CBD) and the
General Agreement on Tariffs and Trade The General Agreement on Tariffs and Trade (GATT) is a legal agreement between many countries, whose overall purpose was to promote international trade by reducing or eliminating trade barriers such as tariffs or quotas. According to its pre ...
(GATT, 1947). The UN
Food and Agriculture Organization The Food and Agriculture Organization of the United Nations (FAO)french: link=no, Organisation des Nations unies pour l'alimentation et l'agriculture; it, Organizzazione delle Nazioni Unite per l'Alimentazione e l'Agricoltura is an intern ...
(FAO), the
International Maritime Organization The International Maritime Organization (IMO, French: ''Organisation maritime internationale'') is a specialised agency of the United Nations responsible for regulating shipping. The IMO was established following agreement at a UN conference ...
(IMO), the Organisation for Economic Co-operation and Development (
OECD The Organisation for Economic Co-operation and Development (OECD; french: Organisation de coopération et de développement économiques, ''OCDE'') is an intergovernmental organisation with 38 member countries, founded in 1961 to stimulate e ...
) and WHO are the most important organisations associated with biosecurity. The IHR is a legally binding agreement on 196 nations, including all member states of WHO. Its purpose and scope is "to prevent, protect against, control, and provide a public health response to the international spread of disease in ways that are commensurate with and restricted to public health risks and that avoid unnecessary interference with international traffic and trade", "to help the international community prevent and respond to acute public health risks that have the potential to cross borders and threaten people worldwide".


Biological weapons

* The
Biological Weapons Convention The Biological Weapons Convention (BWC), or Biological and Toxin Weapons Convention (BTWC), is a disarmament treaty that effectively bans biological and toxin weapons by prohibiting their development, production, acquisition, transfer, stockpil ...
was the first multilateral
disarmament Disarmament is the act of reducing, limiting, or abolishing weapons. Disarmament generally refers to a country's military or specific type of weaponry. Disarmament is often taken to mean total elimination of weapons of mass destruction, such as n ...
treaty banning the production of an entire category of weapons, being
biological weapon A biological agent (also called bio-agent, biological threat agent, biological warfare agent, biological weapon, or bioweapon) is a bacterium, virus, protozoan, parasite, fungus, or toxin that can be used purposefully as a weapon in bioterroris ...
s. * ''UN Resolution 1540'' (2004) "affirms that the proliferation of nuclear, chemical and biological weapons and their means of delivery constitutes a threat to international peace and security. The resolution obliges States, inter alia, to refrain from supporting by any means non-State actors from developing, acquiring, manufacturing, possessing, transporting, transferring or using nuclear, chemical or biological weapons and their means of delivery". Resolution 2325, reaffirming 1540, was adopted unanimously on 15 December 2016.


Laboratory safety

*''OECD Best Practice Guidelines for Biological Resource Centres'', a consensus report created in 2001 after experts from
OECD The Organisation for Economic Co-operation and Development (OECD; french: Organisation de coopération et de développement économiques, ''OCDE'') is an intergovernmental organisation with 38 member countries, founded in 1961 to stimulate e ...
countries came together, calling upon "national governments to undertake actions to bring the BRC concept into being in concert with the international scientific community". BRCs are "repositories and providers of high-quality biological materials and information".


As international security issue

For a long time, health security or biosecurity issues were not considered as an
international security International security, also called global security is a term which refers to the measures taken by states and international organizations, such as the United Nations, European Union, and others, to ensure mutual survival and safety. These meas ...
issue, especially in the traditional view of international relations. However, some changes in trend have contributed to the inclusion of biosecurity (health security) in discussions of security. As time progressed, there was a movement towards securitisation. Non-traditional security issues such as
climate change In common usage, climate change describes global warming—the ongoing increase in global average temperature—and its effects on Earth's climate system. Climate change in a broader sense also includes previous long-term changes to E ...
,
organised crime Organized crime (or organised crime) is a category of transnational, national, or local groupings of highly centralized enterprises run by criminals to engage in illegal activity, most commonly for profit. While organized crime is generally th ...
,
terrorism Terrorism, in its broadest sense, is the use of criminal violence to provoke a state of terror or fear, mostly with the intention to achieve political or religious aims. The term is used in this regard primarily to refer to intentional violen ...
, and
landmine A land mine is an explosive device concealed under or on the ground and designed to destroy or disable enemy targets, ranging from combatants to vehicles and tanks, as they pass over or near it. Such a device is typically detonated automati ...
s came to be included in the definition of international security. There was a general realisation that the actors in the international system not only involved nation-states but also included international organisations, institutions, and individuals, which ensured the security of various actors within each nation became an important agenda. Biosecurity is one of the issues to be securitised under this trend. On 10 January 2000, the
UN Security Council The United Nations Security Council (UNSC) is one of the six principal organs of the United Nations (UN) and is charged with ensuring international peace and security, recommending the admission of new UN members to the General Assembly, and ...
convened to discuss
HIV/AIDS Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual ...
as a security issue in Africa and designated it a threat in the following month. The UNDP
Millennium Development Goals The Millennium Development Goals (MDGs) were eight international development goals for the year 2015 that had been established following the Millennium Summit of the United Nations in 2000, following the adoption of the United Nations Millenniu ...
also recognise health issues as international security issue. Several instances of
epidemic An epidemic (from Ancient Greek, Greek ἐπί ''epi'' "upon or above" and δῆμος ''demos'' "people") is the rapid spread of disease to a large number of patients among a given population within an area in a short period of time. Epidemics ...
s such as
SARS Severe acute respiratory syndrome (SARS) is a viral respiratory disease of zoonotic origin caused by the severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), the first identified strain of the SARS coronavirus species, ''sever ...
increased awareness of health security (biosecurity). Several factors have rendered biosecurity issues more severe: there is a continuing advancement of
biotechnology Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used b ...
, which increases the possibility for malevolent use, evolution of
infectious disease An infection is the invasion of tissues by pathogens, their multiplication, and the reaction of host tissues to the infectious agent and the toxins they produce. An infectious disease, also known as a transmissible disease or communicable di ...
s, and globalising force which is making the world more interdependent and more susceptible to spread of epidemics. Controversial experiments in
synthetic biology Synthetic biology (SynBio) is a multidisciplinary area of research that seeks to create new biological parts, devices, and systems, or to redesign systems that are already found in nature. It is a branch of science that encompasses a broad ran ...
, including the synthesis of
poliovirus A poliovirus, the causative agent of polio (also known as poliomyelitis), is a serotype of the species ''Enterovirus C'', in the family of ''Picornaviridae''. There are three poliovirus serotypes: types 1, 2, and 3. Poliovirus is composed of an ...
from its genetic sequence, and the modification of flu type H5N1 for
airborne transmission Airborne or aerosol transmission is transmission of an infectious disease through small particles suspended in the air. Infectious diseases capable of airborne transmission include many of considerable importance both in human and veterinary ...
in
mammal Mammals () are a group of vertebrate animals constituting the class Mammalia (), characterized by the presence of mammary glands which in females produce milk for feeding (nursing) their young, a neocortex (a region of the brain), fur or ...
s, led to calls for tighter controls on the materials and information used to perform similar feats. Ideas include better enforcement by national governments and private entities concerning shipments and downloads of such materials, and registration or background check requirements for anyone handling such materials.


Challenges

Diseases caused by emerging viruses are a major threat to global
public health Public health is "the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals". Analyzing the det ...
. The proliferation of high biosafety level laboratories around the world has resulted in concern about the availability of targets for those that might be interested in stealing dangerous pathogens. The growth in containment laboratories is often in response to emerging diseases, and many new containment labs' main focus is to find ways to control these diseases. By strengthening national disease surveillance, prevention, control and response systems, the labs have improved international public health. One of the major challenges of biosecurity is that harmful technology has become more available and accessible. Biomedical advances and the globalisation of scientific and technical expertise have made it possible to greatly improve public health; however, there is also the risk that these advances can make it easier for terrorists to produce biological weapons. Communication between the citizen and law enforcement officials is important. Indicators of
agro-terrorism Agroterrorism, also known as agriterrorism and agricultural terrorism, is a malicious attempt to disrupt or destroy the agricultural industry and/or food supply system of a population through "the malicious use of plant or animal pathogens to cause ...
at a food processing plant may include persons taking notes or photos of a business, theft of employee uniforms, employees changing working hours, or persons attempting to gain information about security measures and personnel. Unusual activity is best handled if reported to law enforcement personnel promptly. Communication between
policymaker Policy is a deliberate system of guidelines to guide decisions and achieve rational outcomes. A policy is a statement of intent and is implemented as a procedure or protocol. Policies are generally adopted by a governance body within an organ ...
s and
life sciences This list of life sciences comprises the branches of science that involve the scientific study of life – such as microorganisms, plants, and animals including human beings. This science is one of the two major branches of natural science, the ...
scientists is also important. The
MENA MENA, an acronym in the English language, refers to a grouping of countries situated in and around the Middle East and North Africa. It is also known as WANA, SWANA, or NAWA, which alternatively refers to the Middle East as Western Asia (or a ...
(
Middle East The Middle East ( ar, الشرق الأوسط, ISO 233: ) is a geopolitical region commonly encompassing Arabian Peninsula, Arabia (including the Arabian Peninsula and Bahrain), Anatolia, Asia Minor (Asian part of Turkey except Hatay Pro ...
and
North Africa North Africa, or Northern Africa is a region encompassing the northern portion of the African continent. There is no singularly accepted scope for the region, and it is sometimes defined as stretching from the Atlantic shores of Mauritania in ...
) region, with its socio-political unrest, diverse cultures and societies, and recent biological weapons programs, faces particular challenges.


The future

Biosecurity requires the cooperation of scientists, technicians, policy makers, security engineers, and
law enforcement Law enforcement is the activity of some members of government who act in an organized manner to enforce the law by discovering, deterring, rehabilitating, or punishing people who violate the rules and norms governing that society. The term en ...
officials. The emerging nature of newer biosecurity threats means that small-scale risks can blow up rapidly, which makes the development of an effective policy challenging owing to the limitations on time and resources available for analysing threats and estimating the likelihood of their occurrence. It is likely that further synergies with other disciplines, such as
virology Virology is the Scientific method, scientific study of biological viruses. It is a subfield of microbiology that focuses on their detection, structure, classification and evolution, their methods of infection and exploitation of host (biology), ...
or the detection of
chemical contaminant An adulterant is caused by the act of adulteration, a practice of secretly mixing a substance with another. Typical substances that are adulterated include but are not limited to food, cosmetics, pharmaceuticals, fuel, or other chemicals, t ...
s, will develop over time. Some uncertainties about the policy implementation for biosecurity remain for future. In order to carefully plan out preventive policies, policy makers need to be able to somewhat predict the probability and assess the risks; however, as the uncertain nature of the biosecurity issue goes it is largely difficult to predict and also involves a complex process as it requires a multidisciplinary approach. The policy choices they make to address an immediate threat could pose another threat in the future, facing an unintended trade-off. Philosopher
Toby Ord Toby David Godfrey Ord (born July 1979) is an Australian philosopher. He founded Giving What We Can in 2009, an international society whose members pledge to donate at least 10% of their income to effective charities, and is a key figure in the ...
, in his 2020 book '' The Precipice: Existential Risk and the Future of Humanity'', puts into question whether the current international conventions regarding biotechnology research and development regulation, and self-regulation by biotechnology companies and the scientific community are adequate.


Role of education

The advance of the life sciences and biotechnology has the potential to bring great benefits to humankind through responding to societal challenges. However, it is also possible that such advances could be exploited for hostile purposes, something evidenced in a small number of incidents of bioterrorism, particularly by the series of large-scale offensive
biological warfare Biological warfare, also known as germ warfare, is the use of biological toxins or infectious agents such as bacteria, viruses, insects, and fungi with the intent to kill, harm or incapacitate humans, animals or plants as an act of war. Bio ...
programs carried out by major states in the last century. Dealing with this challenge, which has been labelled the "dual-use dilemma", requires a number of different activities. However, one way of ensuring that the life sciences continue to generate significant benefits and do not become subject to misuse for hostile purposes is a process of engagement between scientists and the security community, and the development of strong ethical and normative frameworks to complement legal and regulatory measures that are developed by states.


See also

* Biodefence *
Biological Weapons Convention The Biological Weapons Convention (BWC), or Biological and Toxin Weapons Convention (BTWC), is a disarmament treaty that effectively bans biological and toxin weapons by prohibiting their development, production, acquisition, transfer, stockpil ...
* Biorisk *
Biosecurity in Australia National biosecurity in Australia is governed and administered by two federal government departments, the Department of Health and thDepartment of Agriculture, Fisheries and Forestry The ''Biosecurity Act 2015'' (C'wealth) and related legislati ...
* Biosecurity in New Zealand * Biosecurity in the United States * Biowar * Cyberbiosecurity *
Food safety Food safety (or food hygiene) is used as a scientific method/discipline describing handling, preparation, and storage of food in ways that prevent food-borne illness. The occurrence of two or more cases of a similar illness resulting from t ...
*
Global health Global health is the health of the populations in the worldwide context; it has been defined as "the area of study, research and practice that places a priority on improving health and achieving equity in health for all people worldwide". Problem ...
*
Global Health Security Initiative The Global Health Security Initiative (GHSI) is an informal international partnership among countries in order to exchange information and coordinate practices for confronting new threats and risks to global health. It was formed to respond to th ...
(GHSI) *
Good Agricultural Practices Good agricultural practice (GAP) is a certification system for agriculture, specifying procedures (and attendant documentation) that must be implemented to create food for consumers or further processing that is safe and wholesome, using sustaina ...
*
Human security Human security is a paradigm for understanding global vulnerabilities whose proponents challenges the traditional notion of national security through military security by arguing that the proper referent for security should be at the human rather th ...
*
International Health Regulations The International Health Regulations (IHR), first adopted by the World Health Assembly in 1969 and last revised in 2005, are a legally binding rules that only apply to the WHO that is an instrument that aims for international collaboration "to pre ...
*
Interplanetary contamination Interplanetary contamination refers to biological contamination of a planetary body by a space probe or spacecraft, either deliberate or unintentional. There are two types of interplanetary contamination: *''Forward contamination'' is the transfer ...
*
Public health Public health is "the science and art of preventing disease, prolonging life and promoting health through the organized efforts and informed choices of society, organizations, public and private, communities and individuals". Analyzing the det ...
*
Quarantine A quarantine is a restriction on the movement of people, animals and goods which is intended to prevent the spread of disease or pests. It is often used in connection to disease and illness, preventing the movement of those who may have been ...
*
Select agent Under United States law, Biological select agents or toxins (BSATs) — or simply select agents for short — are bio-agents which (since 1997) have been declared by the U.S. Department of Health and Human Services (HHS) or by the U.S. Departme ...


References


Further reading


General

* '
Biosecurity Commons
'', a
Wiki A wiki ( ) is an online hypertext publication collaboratively edited and managed by its own audience, using a web browser. A typical wiki contains multiple pages for the subjects or scope of the project, and could be either open to the pu ...
Database * – A peer-reviewed, open access electronic journal for cross-disciplinary research in all aspects of human or animal epidemics, pandemics, biosecurity, bioterrorism and CBRN, including prevention, governance, detection, mitigation and response.


Articles and books

* Chen, Lincoln, Jennifer Leaning, and Vasant Narasimhan, eds. (2003)
''Global Health Challenges for Human Security''
Harvard University Press. * * *Hoyt, Kendall and Brooks, Stephen G. (2003)
"A Double-Edged Sword: Globalization and Biosecurity"
''International Affairs'', Vol. 23, No. 3. * Koblentz, Gregory D. (2012)
"From biodefence to biosecurity: the Obama administration's strategy for countering biological threats"
''International Affairs'', Vol. 88, Issue 1. * Lakoff, Andrew, and Sorensen, Georg. (October 2008). ''Biosecurity Interventions: Global Health and Security in Question'', Columbia University Press, . (Detail
here
) *Paris, Roland. (2001)
"Human Security: Paradigm Shift or Hot Air?"
''International Affairs'', Vol. 26, No. 2. * Tadjbakhsh, Shahrbanou. and Chenoy, Anuradha. (2007). ''Human Security: Concepts and Implications''. New York, Routledge. p. 42. (Also 2005 articl
here


External links


Biosecurity
at the FAO
Canadian Food Inspection Agency

OIE Biological Threat Reduction Strategy
(
World Organisation for Animal Health The World Organisation for Animal Health (WOAH), formerly the (OIE), is an intergovernmental organization coordinating, supporting and promoting animal disease control. Mission and status The main objective of the WOAH is to control epizo ...
) {{Sustainability