Big Seven Conference may refer to:
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Big Eight Conference
The Big Eight Conference was a National Collegiate Athletic Association (NCAA)-affiliated Division I-A college athletic association that sponsored football. It was formed in January 1907 as the Missouri Valley Intercollegiate Athletic Associatio ...
, an unofficial name used in the 1948–1957 era
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Skyline Conference (1938–1962) (officially the Mountain States Athletic Conference and also known informally as the Mountain States Conference), an unofficial name used in the 1938–1947 era
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