Bietaserpine (
INN
Inns are generally establishments or buildings where travelers can seek lodging, and usually, food and drink. Inns are typically located in the country or along a highway; before the advent of motorized transportation they also provided accommo ...
), or 1-
-(diethylamino)ethyleserpine, is a derivative of
reserpine
Reserpine is a drug that is used for the treatment of high blood pressure, usually in combination with a thiazide diuretic or vasodilator. Large clinical trials have shown that combined treatment with reserpine plus a thiazide diuretic reduces m ...
used as an
antihypertensive agent
Antihypertensives are a class of drugs that are used to treat hypertension (high blood pressure). Antihypertensive therapy seeks to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Evidence suggests that r ...
. Like reserpine, bietaserpine is a
VMAT
The vesicular monoamine transporter (VMAT) is a transport protein integrated into the membranes of synaptic vesicles of presynaptic neurons. It transports monoamine neurotransmitters – such as dopamine, serotonin, norepinephrine, epinephri ...
inhibitor.
[Buckingham J ''et al.'' (eds.) (1993). ]
Dictionary of Natural Products
', vol. 5, p. 4923, Boca Raton: Chapman & Hall/CRC. . Retrieved on June 22, 2009 through Google Book Search
Google Books (previously known as Google Book Search, Google Print, and by its code-name Project Ocean) is a service from Google Inc. that searches the full text of books and magazines that Google has scanned, converted to text using optical c ...
.
References
Antihypertensive agents
Benzoate esters
Diethylamino compounds
Monoamine-depleting agents
Pyrogallol ethers
VMAT inhibitors
{{Antihypertensive-stub