The Bielschowsky technique is a silver staining method used in histochemistry for the visualization of nerve fibers, including multipolar interneurons in the
cerebellum
The cerebellum (Latin for "little brain") is a major feature of the hindbrain of all vertebrates. Although usually smaller than the cerebrum, in some animals such as the mormyrid fishes it may be as large as or even larger. In humans, the cerebel ...
.
The method is attributed to German neurologist and neurohistologist
Max Bielschowsky
Max Israel Bielschowsky (20 February 1869 – 15 August 1940) was a German neuropathologist born in Breslau.
After receiving his medical doctorate from the University of Munich in 1893, he worked with Ludwig Edinger (1855–1918) at the ...
(1869–1940), who made improvements over the previous method developed by
Ramon y Cajal (1852–1934).
See also
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Immunohistochemistry
Immunohistochemistry (IHC) is the most common application of immunostaining. It involves the process of selectively identifying antigens (proteins) in cells of a tissue section by exploiting the principle of antibodies binding specifically to an ...
*
Luxol fast blue stain
*
Neurofilament
Neurofilaments (NF) are classed as type IV intermediate filaments found in the cytoplasm of neurons. They are protein polymers measuring 10 nm in diameter and many micrometers in length. Together with microtubules (~25 nm) and mi ...
References
{{Stains
Staining
Histochemistry
Histology