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3-Oxopentanoic acid, or ''beta''-ketopentanoate, is a 5-carbon
ketone body Ketone bodies are water-soluble molecules that contain the ketone groups produced from fatty acids by the liver (ketogenesis). Ketone bodies are readily transported into tissues outside the liver, where they are converted into acetyl-CoA (acetyl ...
. It is made from odd carbon fatty acids in the liver and rapidly enters the brain. As opposed to 4-carbon ketone bodies, ''beta''-ketopentanoate is anaplerotic, meaning it can refill the pool of
TCA cycle The citric acid cycle (CAC)—also known as the Krebs cycle or the TCA cycle (tricarboxylic acid cycle)—is a series of chemical reactions to release stored energy through the oxidation of acetyl-CoA derived from carbohydrates, fats, and proteins ...
intermediates. The triglyceride
triheptanoin Triheptanoin, sold under the brand name Dojolvi, is a medication for the treatment of children and adults with molecularly confirmed long-chain fatty acid oxidation disorders (LC-FAOD). The most common adverse reactions include abdominal pain, d ...
is used clinically to produce ''beta''-ketopentanoate.
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References

{{DEFAULTSORT:Oxopentanoic acid, 3- Beta-keto acids Carboxylic acids