Bert Fraser-Reid
   HOME

TheInfoList



OR:

Bertram Oliver "Bert" Fraser-Reid (23 February 1934 – 25 May 2020) was a Jamaican synthetic organic chemist who has been widely recognised for his work using
carbohydrates In organic chemistry, a carbohydrate () is a biomolecule consisting of carbon (C), hydrogen (H) and oxygen (O) atoms, usually with a hydrogen–oxygen atom ratio of 2:1 (as in water) and thus with the empirical formula (where ''m'' may or may ...
as starting materials for chiral materials and on the role of oligosaccharides in immune response.


Early life

Fraser-Reid was born in
Coleyville Coleyville is a settlement in Jamaica. It is located in Manchester Parish The Parish of Manchester is a parish located in west-central Jamaica, in the county of Middlesex. Its capital, Mandeville, is a major business centre. Its St. Paul ...
, Jamaica to William, an elementary school principal, and Laura, a teacher. He had five older siblings. Laura died when Fraser-Reid was only nine months old. He attended Excelsior High School and Clarendon College before moving to Canada to earn BSc (1959) and MSc (1961) at
Queen's University Queen's or Queens University may refer to: *Queen's University at Kingston, Ontario, Canada *Queen's University Belfast, Northern Ireland, UK **Queen's University of Belfast (UK Parliament constituency) (1918–1950) **Queen's University of Belfast ...
in Ontario He went to University of Alberta to earn a PhD in 1964 under the supervision of
Raymond Lemieux Raymond Urgel Lemieux, Order of Canada, CC, Alberta Order of Excellence, AOE, Royal Society, FRS (June 16, 1920 – July 22, 2000) was a Canadians, Canadian organic chemist, who pioneered many discoveries in the field of chemistry, his first and ...
. He went to Imperial College London to do postdoctoral work for Nobel Laureate
Sir Derek Barton Sir Derek Harold Richard Barton (8 September 1918 – 16 March 1998) was an English organic chemist and Nobel Prize laureate for 1969. Education and early life Barton was born in Gravesend, Kent, to William Thomas and Maude Henrietta Barton ( ...
from 1964 to 1966.


Academic career

From 1966 to 1980 Fraser-Reid was on the faculty of the University of Waterloo in Waterloo, Ontario where he established a research group known as "Fraser-Reid's Rowdies". The primary emphasis of his work at this point was the synthesis of chiral natural products using
carbohydrates In organic chemistry, a carbohydrate () is a biomolecule consisting of carbon (C), hydrogen (H) and oxygen (O) atoms, usually with a hydrogen–oxygen atom ratio of 2:1 (as in water) and thus with the empirical formula (where ''m'' may or may ...
as the starting materials. In 1975, Fraser-Reid was the first to publish a method for making nonsugar compounds with simple sugars. In 1980, he was hired at the University of Maryland, College Park, and then at
Duke University Duke University is a private research university in Durham, North Carolina. Founded by Methodists and Quakers in the present-day city of Trinity in 1838, the school moved to Durham in 1892. In 1924, tobacco and electric power industrialist James ...
in North Carolina in 1983. In 1985 he was appointed the
James B. Duke Professor At Duke University, the title of James B. Duke Professor is given to a small number of the faculty with extraordinary records of achievement. At some universities, titles like "distinguished professor", "institute professor", or " regents professo ...
of Chemistry. At Duke University, his research shifted to exploring the role of oligosaccharides in immune responses, and particularly on the effect of molecules on human diseases like malaria and
AIDS Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual m ...
. After retiring from Duke in 1996, due to an undisclosed harassment claim, he established the Natural Products & Glycotechnology Research Institute, a nonprofit, to study the carbohydrate chemistry/biology of tropical parasitic diseases in developing countries and to develop a carbohydrate-based malaria vaccine. Fraser-Reid and his team achieved a milestone in oligosaccharide synthesis by assembling a molecule consisting of 28
monosaccharide Monosaccharides (from Greek ''monos'': single, '' sacchar'': sugar), also called simple sugars, are the simplest forms of sugar and the most basic units (monomers) from which all carbohydrates are built. They are usually colorless, water-solub ...
units.


Achievements

Several sources have reported that Fraser-Reid was nominated in 1998 for a Nobel Prize in chemistry for his work on oligosaccharides and immune responses. This statement cannot be verified since the names of the nominees are never publicly announced, and neither are they told that they have been considered for the Prize. Nomination records are sealed for fifty years. The Institute of Jamaica awarded Fraser-Reid the 2007 Musgrave Medal (Gold) for his work in chemistry, noting that during his career he co-authored over 330
peer-reviewed Peer review is the evaluation of work by one or more people with similar competencies as the producers of the work (peers). It functions as a form of self-regulation by qualified members of a profession within the relevant field. Peer review ...
publications and supervised 85 post-doctoral fellows and 55 PhD students.


Other interests

Along with his interest in science, Fraser-Reid was an accomplished pianist and organist who gave recitals at notable venues such as St. George's Cathedral, Kingston, Jamaica (December 1986) and Cathedral de Seville, Spain (August 1995). In the 1970s Fraser-Reid filed a lawsuit against a building contractor who had not followed municipal building codes. The case went all the way to the
Supreme Court of Canada The Supreme Court of Canada (SCC; french: Cour suprême du Canada, CSC) is the Supreme court, highest court in the Court system of Canada, judicial system of Canada. It comprises List of Justices of the Supreme Court of Canada, nine justices, wh ...
where Fraser-Reid prevailed, and "Fraser-Reid v Droumtsekas" is often cited in Canadian civil law.


See also

* List of University of Waterloo people


References

{{DEFAULTSORT:Fraser-Reid, Bertram 1934 births 2020 deaths Organic chemists Jamaican academics Emigrants from British Jamaica to Canada Canadian chemists University of Waterloo faculty Duke University faculty Recipients of the Musgrave Medal Male organists Queen's University at Kingston alumni University of Alberta alumni 21st-century Canadian pianists 21st-century organists 21st-century chemists 21st-century Canadian male musicians People from Manchester Parish