Berruguete is a surname. Notable people with the surname include:
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Alonso Berruguete
Alonso González de Berruguete (Alonso Berruguete) (c. 1488 – 1561) was a Spanish painter, sculptor and architect. He is considered to be the most important sculptor of the Spanish Renaissance, and is known for his emotive sculptures depict ...
( 1488–1561), Spanish painter
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Pedro Berruguete
Pedro Berruguete (c. 1450 – 1504) was a Spanish painter whose art is regarded as a transitional style between gothic and Renaissance art. Berruguete most famously created paintings of the first few years of the Inquisition and of religious i ...
( 1450–1504), Spanish painter, father of Alonso
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