Bencyclane Synthesis
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Bencyclane is an
antispasmodic An antispasmodic (synonym: spasmolytic) is a pharmaceutical drug or other agent that suppresses muscle spasms. Smooth muscle spasm One type of antispasmodics is used for smooth muscle relaxation, especially in tubular organs of the gastrointest ...
, vasodilator, and
platelet aggregation inhibitor An antiplatelet drug (antiaggregant), also known as a platelet agglutination inhibitor or platelet aggregation inhibitor, is a member of a class of pharmaceuticals that decrease platelet aggregation and inhibit thrombus formation. They are effectiv ...
.


Synthesis

Grignard addition of benzylmagnesiumbromide to suberone would give 1-benzylcycloheptanol 006-73-9(1'). Williamson ether synthesis with 3-dimethylaminopropylchloride 09-54-6(2) completed the synthesis of bencyclane (3).


See also

* Clofenciclan


References

Calcium channel blockers Ethers Dimethylamino compounds {{Amine-stub