Beevers–Lipson Strip
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Beevers–Lipson strips were a computational aid for early
crystallographers A crystallographer is a type of scientist who practices crystallography, in other words, who studies crystals. Career paths The work of crystallographers spans several academic disciplines, including the life sciences, chemistry, physics, and m ...
in calculating
Fourier transform In mathematics, the Fourier transform (FT) is an integral transform that takes a function as input then outputs another function that describes the extent to which various frequencies are present in the original function. The output of the tr ...
s to determine the structure of
crystal A crystal or crystalline solid is a solid material whose constituents (such as atoms, molecules, or ions) are arranged in a highly ordered microscopic structure, forming a crystal lattice that extends in all directions. In addition, macros ...
s from crystallographic data, enabling the creation of models for complex molecules. They were used from the 1930s until computers with enough power became generally available in the 1960s. The technique was developed by
C. Arnold Beevers Cecil Arnold Beevers (27 May 1908 – 16 January 2001) was a British crystallographer, known for Beevers–Lipson strips, a computational aid for calculating Fourier transforms to determine the structure of crystals from crystallographic data ...
(1908–2001), reader in
crystallography Crystallography is the branch of science devoted to the study of molecular and crystalline structure and properties. The word ''crystallography'' is derived from the Ancient Greek word (; "clear ice, rock-crystal"), and (; "to write"). In J ...
at the
University of Edinburgh The University of Edinburgh (, ; abbreviated as ''Edin.'' in Post-nominal letters, post-nominals) is a Public university, public research university based in Edinburgh, Scotland. Founded by the City of Edinburgh Council, town council under th ...
, and Henry Lipson CBE FRS (1910–1991), Professor of
Physics Physics is the scientific study of matter, its Elementary particle, fundamental constituents, its motion and behavior through space and time, and the related entities of energy and force. "Physical science is that department of knowledge whi ...
at the
University of Manchester Institute of Science and Technology The University of Manchester Institute of Science and Technology (UMIST) was a university based in the centre of the city of Manchester in England. It specialised in technical and scientific subjects and was a major centre for Research univer ...
. The approach converted the sizable calculations of multi-dimensional Fourier summations needed in crystallography analysis into sums of more manageable one-dimensional values. The folded card strips with numbers were typically stored in two wooden boxes, one for
sine In mathematics, sine and cosine are trigonometric functions of an angle. The sine and cosine of an acute angle are defined in the context of a right triangle: for the specified angle, its sine is the ratio of the length of the side opposite th ...
s and one for
cosine In mathematics, sine and cosine are trigonometric functions of an angle. The sine and cosine of an acute angle are defined in the context of a right triangle: for the specified angle, its sine is the ratio of the length of the side opposite that ...
s. Previously it was necessary to consult sine/cosine tables, a time-consuming process. The approach was used by the
Nobel Prize The Nobel Prizes ( ; ; ) are awards administered by the Nobel Foundation and granted in accordance with the principle of "for the greatest benefit to humankind". The prizes were first awarded in 1901, marking the fifth anniversary of Alfred N ...
winner
Dorothy Hodgkin Dorothy Mary Crowfoot Hodgkin (née Crowfoot; 12 May 1910 – 29 July 1994) was a Nobel Prize-winning English chemist who advanced the technique of X-ray crystallography to determine the structure of biomolecules, which became essential for ...
OM FRS (1910–1994). The technique is still used in modern computer programs.


See also

*
X-ray crystallography X-ray crystallography is the experimental science of determining the atomic and molecular structure of a crystal, in which the crystalline structure causes a beam of incident X-rays to Diffraction, diffract in specific directions. By measuring th ...


References


External links

{{DEFAULTSORT:Beevers-Lipson strip Crystallography Mathematical tools Fourier analysis History of chemistry History of the University of Edinburgh University of Manchester