Professor Basil Charles Leicester Weedon

CBE The Most Excellent Order of the British Empire is a British order of chivalry, rewarding contributions to the arts and sciences, work with charitable and welfare organisations, and public service outside the civil service. It was established o ...

, FRS (18 July 1923 – 10 October 2003) was an

organic chemist Organic chemistry is a subdiscipline within chemistry involving the scientific study of the structure, properties, and reactions of organic compounds and organic materials, i.e., matter in its various forms that contain carbon atoms.Clayden, J. ...

and

university A university () is an institution of higher (or tertiary) education and research which awards academic degrees in several academic disciplines. Universities typically offer both undergraduate and postgraduate programs. In the United States, t ...

administrator. Using

nuclear magnetic resonance spectroscopy Nuclear magnetic resonance spectroscopy, most commonly known as NMR spectroscopy or magnetic resonance spectroscopy (MRS), is a spectroscopic technique to observe local magnetic fields around atomic nuclei. The sample is placed in a magnetic fiel ...

, he was the first to map the structures of carotenoid pigments, including

astaxanthin Astaxanthin is a keto- carotenoid within a group of chemical compounds known as terpenes. Astaxanthin is a metabolite of zeaxanthin and canthaxanthin, containing both hydroxyl and ketone functional groups. It is a lipid-soluble pigment with r ...

, rubixanthin and canthaxanthin.

Personal life

Weedon was born in

Wimbledon Wimbledon most often refers to: * Wimbledon, London, a district of southwest London * Wimbledon Championships, the oldest tennis tournament in the world and one of the four Grand Slam championships Wimbledon may also refer to: Places London * ...

, his father was a

dentist A dentist, also known as a dental surgeon, is a health care professional who specializes in dentistry (the diagnosis, prevention, management, and treatment of diseases and conditions of the mouth, oral cavity and other aspects of the craniofaci ...

and his mother came from a family of prosperous

jeweller A bench jeweler is an artisan who uses a combination of skills to make and repair jewelry. Some of the more common skills that a bench jeweler might employ include antique restoration, silversmith, Goldsmith, stone setting, engraving, fabrica ...

s. His parents separated when he was nine years old and he remained living with his father, within a few years he had lost all contact with his mother and his younger sister. During

World War II World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposin ...

, he was evacuated to a farm near

Guildford Guildford () is a town in west Surrey, around southwest of central London. As of the 2011 census, the town has a population of about 77,000 and is the seat of the wider Borough of Guildford, which had around inhabitants in . The name "Guildf ...

. His wife, Barbara Dawe, served in the

Women's Royal Navy Service The Women's Royal Naval Service (WRNS; popularly and officially known as the Wrens) was the women's branch of the United Kingdom's Royal Navy. First formed in 1917 for the First World War, it was disbanded in 1919, then revived in 1939 at the ...

during World War II, whilst working there she met Basil's cousin and later Basil. They married in 1959 and had two children, Sarah and Matthew. Weedon suffered from

Parkinson's disease Parkinson's disease (PD), or simply Parkinson's, is a long-term degenerative disorder of the central nervous system that mainly affects the motor system. The symptoms usually emerge slowly, and as the disease worsens, non-motor symptoms becom ...

in his later years.

Academic life

He attended Wandsworth Grammar School in South London, then a school in Guildford, prior to studying chemistry at

Imperial College, London Imperial College London (legally Imperial College of Science, Technology and Medicine) is a public research university in London, United Kingdom. Its history began with Prince Albert, consort of Queen Victoria, who developed his vision for a cu ...

in 1940. He was awarded his degree just two years later, aged 19. He remained at Imperial College, studying for a PhD before taking a job with ICI working on dyes in

Blackley Blackley is a suburban area of Manchester, England. Historically in Lancashire, it is approximately north of Manchester city centre, on the River Irk. History The hamlet of Blackley was mentioned in the Domesday Book. The name derives from ...

Manchester Manchester () is a city in Greater Manchester, England. It had a population of 552,000 in 2021. It is bordered by the Cheshire Plain to the south, the Pennines to the north and east, and the neighbouring city of Salford to the west. The t ...

. He returned to Imperial College in 1947 as a lecturer in organic chemistry and became a reader in 1955. In 1960 he was appointed the Chair of organic chemistry at

Queen Mary College , mottoeng = With united powers , established = 1785 – The London Hospital Medical College1843 – St Bartholomew's Hospital Medical College1882 – Westfield College1887 – East London College/Queen Mary College , type = Public researc ...

. In 1976 he became the 4th

Vice-Chancellor A chancellor is a leader of a college or university, usually either the executive or ceremonial head of the university or of a university campus within a university system. In most Commonwealth of Nations, Commonwealth and former Commonwealth n ...

of the

University of Nottingham The University of Nottingham is a public university, public research university in Nottingham, United Kingdom. It was founded as University College Nottingham in 1881, and was granted a royal charter in 1948. The University of Nottingham belongs t ...

, a position he held until his retirement in 1988. He was a consultant to

Hoffmann-La Roche F. Hoffmann-La Roche AG, commonly known as Roche, is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has shares listed on the SIX ...

, Basel, Switzerland between 1955 and 1978.

Scientific discoveries

Weedon, in collaboration with L. M. Jackman, was the first to use nuclear magnetic resonance spectroscopy to study the structures of carotenoids. He also worked on the synthesis of carotenoids and in 1953 described the synthesis of methylbixin which was produced by exposing

bixin Bixin is an apocarotenoid found in the seeds of the achiote tree (''Bixa orellana'') from which it derives its name. It is commonly extracted from the seeds to form annatto, a natural food coloring, containing about 5% pigments of which 70-80% ar ...

from ''

Bixa orellana ''Bixa orellana'', also known as achiote, is a shrub native to Central America. ''Bixa orellana'' is grown in many countries worldwide. The tree is best known as the source of annatto, a natural orange-red condiment (also called or ) obtained ...

'' to

iodine Iodine is a chemical element with the symbol I and atomic number 53. The heaviest of the stable halogens, it exists as a semi-lustrous, non-metallic solid at standard conditions that melts to form a deep violet liquid at , and boils to a vi ...

; later he successfully synthesised bixin using the

Wittig reaction The Wittig reaction or Wittig olefination is a chemical reaction of an aldehyde or ketone with a triphenyl phosphonium ylide called a Wittig reagent. Wittig reactions are most commonly used to convert aldehydes and ketones to alkenes. Mos ...

. During the 1960s and 1970s, Weedon's research group elucidated the structures of and synthesised a wide range of naturally occurring carotenoids. These included, canthaxanthin (responsible for the pink colour of

flamingo Flamingos or flamingoes are a type of Wader, wading bird in the Family (biology), family Phoenicopteridae, which is the only extant family in the order Phoenicopteriformes. There are four flamingo species distributed throughout the Americas ...

s),

(responsible for the colour of

lobster Lobsters are a family (biology), family (Nephropidae, Synonym (taxonomy), synonym Homaridae) of marine crustaceans. They have long bodies with muscular tails and live in crevices or burrows on the sea floor. Three of their five pairs of legs ...

s),

capsanthin Capsanthin is a natural red dye of the xanthophyll class of carotenoids. As a food coloring, it has the E number E160c(i). Capsanthin is the main carotenoid in the ''Capsicum annuum'' species of plants including red bell pepper, New Mexico chile ...

and

capsorubin Capsorubin is a natural red dye of the xanthophyll class. As a food coloring, it has the E number E160c(ii). Capsorubin is a carotenoid found in red bell pepper (''Capsicum annuum'') and a component of paprika oleoresin Paprika oleoresin (als ...

(found in

red peppers ''Red Peppers'', described as "an interlude with music", is a short comic play in two scenes by Noël Coward. It is one of ten short plays that make up '' Tonight at 8.30'', a cycle written to be performed in groups of three plays across three ...

), renieratene (from Japanese

sea sponges Sponges, the members of the phylum Porifera (; meaning 'pore bearer'), are a basal animal clade as a sister of the diploblasts. They are multicellular organisms that have bodies full of pores and channels allowing water to circulate through ...

) and

fucoxanthin Fucoxanthin is a xanthophyll, with formula C42H58O6. It is found as an accessory pigment in the chloroplasts of brown algae and most other heterokonts, giving them a brown or olive-green color. Fucoxanthin absorbs light primarily in the blue-green ...

(the most abundant carotenoid found in

seaweed Seaweed, or macroalgae, refers to thousands of species of macroscopic, multicellular, marine algae. The term includes some types of '' Rhodophyta'' (red), ''Phaeophyta'' (brown) and ''Chlorophyta'' (green) macroalgae. Seaweed species such as ...

). Other compounds whose structures were discovered include alloxanthin, mytiloxanthin, decaprenoxanthin and violerythrin.

Honours and awards

*1952 -

Meldola Medal The Meldola Medal and Prize was awarded annually from 1921 to 1979 by the Chemical Society and from 1980 to 2008 by the Royal Society of Chemistry to a British chemist who was under 32 years of age for promising original investigations in chemistr ...

of the

Royal Institute of Chemistry The Royal Institute of Chemistry was a British scientific organisation. Founded in 1877 as the Institute of Chemistry of Great Britain and Ireland (ICGBI), its role was to focus on qualifications and the professional status of chemists, and its aim ...

*1971 - Elected a Fellow of the

Royal Society The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, re ...

*1974 - Appointed a

Commander of the Order of the British Empire The Most Excellent Order of the British Empire is a British order of chivalry, rewarding contributions to the arts and sciences, work with charitable and welfare organisations, and public service outside the civil service. It was established o ...

References

External links

Biographical Database of the British Chemical CommunityBasil Weedon's biography in this database
{{DEFAULTSORT:Weedon, Basil Vice-Chancellors of the University of Nottingham Commanders of the Order of the British Empire Fellows of the Royal Society 1923 births 2003 deaths Academics of Queen Mary University of London