Barbara Kathryn Burgess (December 31, 1950 – December 30, 2001) was an American biologist known for her work in the fields of metallobiochemistry and

nitrogen fixation Nitrogen fixation is a chemical process by which molecular nitrogen (), with a strong triple covalent bond, in the air is converted into ammonia () or related nitrogenous compounds, typically in soil or aquatic systems but also in industry. Atmo ...

. She was a Professor of Molecular Biology and Biochemistry at

University of California, Irvine The University of California, Irvine (UCI or UC Irvine) is a public land-grant research university in Irvine, California. One of the ten campuses of the University of California system, UCI offers 87 undergraduate degrees and 129 graduate and pr ...

Early life and education

Burgess was born and raised in

Cleveland Cleveland ( ), officially the City of Cleveland, is a city in the U.S. state of Ohio and the county seat of Cuyahoga County. Located in the northeastern part of the state, it is situated along the southern shore of Lake Erie, across the U.S. ...

and attended public school throughout her childhood. She matriculated at

Purdue University Purdue University is a public land-grant research university in West Lafayette, Indiana, and the flagship campus of the Purdue University system. The university was founded in 1869 after Lafayette businessman John Purdue donated land and money ...

at the age of 17 and graduated in three years; she remained there for her doctoral studies in

biochemistry Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and ...

and

microbiology Microbiology () is the scientific study of microorganisms, those being unicellular (single cell), multicellular (cell colony), or acellular (lacking cells). Microbiology encompasses numerous sub-disciplines including virology, bacteriology, prot ...

and graduated with her

Ph.D. A Doctor of Philosophy (PhD, Ph.D., or DPhil; Latin: or ') is the most common degree at the highest academic level awarded following a course of study. PhDs are awarded for programs across the whole breadth of academic fields. Because it is a ...

at 25. Her doctoral thesis concerned nitrogen fixation and the mechanisms involved in each reaction.

Career and research

After a brief stint at the Kettering Research Lab in

Yellow Springs, Ohio Yellow Springs is a village in Greene County, Ohio, United States. The population was 3,697 at the 2020 census. It is part of the Dayton Metropolitan Statistical Area. It is home to Antioch College. History The area of the village had long b ...

, Burgess moved to the

to continue her work with ''

Azotobacter ''Azotobacter'' is a genus of usually motile, oval or spherical bacteria that form thick-walled cysts (and also has hard crust) and may produce large quantities of capsular slime. They are aerobic, free-living soil microbes that play an importan ...

metalloenzyme Metalloprotein is a generic term for a protein that contains a metal ion cofactor. A large proportion of all proteins are part of this category. For instance, at least 1000 human proteins (out of ~20,000) contain zinc-binding protein domains al ...

s and

nitrogenase Nitrogenases are enzymes () that are produced by certain bacteria, such as cyanobacteria (blue-green bacteria) and rhizobacteria. These enzymes are responsible for the Organic redox reaction, reduction of nitrogen (N2) to ammonia (NH3). Nitrog ...

. Her work also influenced the field of

iron-sulfur protein Iron–sulfur proteins (or iron–sulphur proteins in British spelling) are proteins characterized by the presence of iron–sulfur clusters containing sulfide-linked di-, tri-, and tetrairon centers in variable oxidation states. Iron–sulfur clu ...

s. She was recognized by her peers as a leader in nitrogen fixation and served as Chair of the NIH Study Section on Metallobiochemistry and Chair of the 2001 Gordon Conference on Metals in Biology. She took her own life on December 30, 2001, leaving a husband and 3 children.

Honors and awards

*1998 Guggenheim Fellow * Fulbright Fellow * Fellow,

American Association for the Advancement of Science The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific respons ...

* Lauds and Laurels Faculty Achievement Award, UC Irvine (posthumous) * Chair, National Institutes of Health Study Section on Metallobiochemistry

References

{{DEFAULTSORT:Burgess, Barbara 1950 births 2001 deaths Purdue University alumni Scientists from Cleveland American biologists 20th-century biologists

Early life and education

Career and research

Honors and awards

See also

References