BAPTA (1,2-bis(''o''- amino phenoxy)

ethane Ethane ( , ) is an organic chemical compound with chemical formula . At standard temperature and pressure, ethane is a colorless, odorless gas. Like many hydrocarbons, ethane is isolated on an industrial scale from natural gas and as a petro ...

-''N'',''N'',''N′'',''N′''-tetra acetic acid) is a

calcium Calcium is a chemical element with the symbol Ca and atomic number 20. As an alkaline earth metal, calcium is a reactive metal that forms a dark oxide-nitride layer when exposed to air. Its physical and chemical properties are most similar t ...

-specific

aminopolycarboxylic acid left, 120px, a metal complex with the EDTA anion 120px, Aspartic acid is an aminodicarboxylic acid and precursor to other ligands. An aminopolycarboxylic acid (sometimes abbreviated APCA) is a chemical compound containing one or more nitrogen at ...

. The presence of four

carboxylic acid In organic chemistry, a carboxylic acid is an organic acid that contains a carboxyl group () attached to an R-group. The general formula of a carboxylic acid is or , with R referring to the alkyl, alkenyl, aryl, or other group. Carboxyl ...

functional group In organic chemistry, a functional group is a substituent or moiety in a molecule that causes the molecule's characteristic chemical reactions. The same functional group will undergo the same or similar chemical reactions regardless of the res ...

s makes possible the binding of two calcium ions. The extensive flexibility of the carboxylate ligands is critical to the coordination of calcium and other metal ions. Due to its properties, it is used in research to chelate Ca²⁺, similarly to EGTA and

EDTA Ethylenediaminetetraacetic acid (EDTA) is an aminopolycarboxylic acid with the formula H2N(CH2CO2H)2sub>2. This white, water-soluble solid is widely used to bind to iron (Fe2+/Fe3+) and calcium ions (Ca2+), forming water-soluble complexes ev ...

. There is a range of reported values for the dissociation constant of BAPTA, though 0.2 μM appears consistently. The rate constant for calcium binding is 500 μM⁻¹ s⁻¹.

References

{{DEFAULTSORT:Bapta Anilines Carboxylic acids Chelating agents Phenol ethers Glycol ethers

See also

References