BSPP is a compound used in scientific research which acts as a
positive allosteric modulator
In pharmacology and biochemistry, allosteric modulators are a group of substances that bind to a receptor to change that receptor's response to stimulus. Some of them, like benzodiazepines, are drugs. The site that an allosteric modulator binds to ...
at the
GABAB receptor
Receptor may refer to:
* Sensory receptor, in physiology, any structure which, on receiving environmental stimuli, produces an informative nerve impulse
*Receptor (biochemistry), in biochemistry, a protein molecule that receives and responds to a ...
.
It has a synergistic effect with GABA
B agonists such as
baclofen
Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity such as from a spinal cord injury or multiple sclerosis. It may also be used for hiccups and muscle spasms near the end of life. It is ta ...
at GABA
B autoreceptors but not heteroreceptors, suggesting it may be useful for distinguishing between these GABA
B receptor subtypes.
References
Phenols
Primary alcohols
GABAB receptor positive allosteric modulators
Tert-butyl compounds
Cyclopentanes
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