BRL-52537 is a drug which acts as a potent and highly selective
κ-opioid agonist
An agonist is a chemical that activates a receptor to produce a biological response. Receptors are cellular proteins whose activation causes the cell to modify what it is currently doing. In contrast, an antagonist blocks the action of the ago ...
.
It has
neuroprotective effects in animal studies,
and is used for research into potential treatments for
stroke
A stroke is a medical condition in which poor blood flow to the brain causes cell death. There are two main types of stroke: ischemic, due to lack of blood flow, and hemorrhagic, due to bleeding. Both cause parts of the brain to stop functionin ...
and
heart attack as well as more general brain research.
References
Synthetic opioids
Chlorobenzenes
Acetamides
Piperidines
Pyrrolidines
Kappa-opioid receptor agonists
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