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Anthony Atala,
M.D. Doctor of Medicine (abbreviated M.D., from the Latin ''Medicinae Doctor'') is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a professional degree. ...
, (born July 14, 1958) is an American bioengineer,
urologist Urology (from Greek οὖρον ''ouron'' "urine" and '' -logia'' "study of"), also known as genitourinary surgery, is the branch of medicine that focuses on surgical and medical diseases of the urinary-tract system and the reproductive org ...
, and
pediatric surgeon Pediatric surgery is a subspecialty of surgery involving the surgery of fetuses, infants, children, adolescents, and young adults. History Pediatric surgery arose in the middle of the 1879 century as the surgical care of birth defects required ...
. He is the W.H. Boyce professor of urology, the founding director of the Wake Forest Institute for Regenerative Medicine, and the chair of the Department of
Urology Urology (from Greek οὖρον ''ouron'' "urine" and '' -logia'' "study of"), also known as genitourinary surgery, is the branch of medicine that focuses on surgical and medical diseases of the urinary-tract system and the reproductive org ...
at
Wake Forest School of Medicine Wake Forest University School of Medicine is the medical school of Wake Forest University, with two campuses located in Winston-Salem, North Carolina and Charlotte, North Carolina, United States. It is affiliated with Atrium Health Wake Forest B ...
in
North Carolina North Carolina () is a state in the Southeastern region of the United States. The state is the 28th largest and 9th-most populous of the United States. It is bordered by Virginia to the north, the Atlantic Ocean to the east, Georgia and ...
. His work focuses on the science of
regenerative medicine Regenerative medicine deals with the "process of replacing, engineering or regenerating human or animal cells, tissues or organs to restore or establish normal function". This field holds the promise of engineering damaged tissues and organs by st ...
: "a practice that aims to refurbish diseased or damaged tissue using the body's own healthy cells". Dr. Atala is the creator of the first 3D bioprinters (Integrated Tissue and Organ Printing System or ITOP) and is one of the foremost leading figures in the field of
organ printing Organ printing utilizes techniques similar to conventional 3D printing where a computer model is fed into a printer that lays down successive layers of plastics or wax until a 3D object is produced. In the case of organ printing, the material bein ...
. Atala and his team developed the first lab-grown organ (a bladder) to be implanted into a human. He is also developing experimental technology that can 3D print human tissue on demand. As director of the Wake Forest Institute for Regenerative Medicine, Dr. Atala leads a team of more than 400 researchers dedicated to developing cell therapies and engineering replacement tissues and organs for more than 40 different areas of the body. Dr. Atala is editor of 3 journals and 25 books including ''Principles of Regenerative Medicine'', ''Foundations of Regenerative Medicine'', ''Methods of Tissue Engineering'' and ''Minimally Invasive Urology''. He has published over 800 journal articles and has received more than 250 national and international patents. Fifteen technology applications developed in Dr. Atala's laboratory have been used clinically. He serves on the editorial board of the scientific journal ''
Rejuvenation Research ''Rejuvenation Research'' is a bimonthly peer-reviewed scientific journal published by Mary Ann Liebert that covers research on rejuvenation and biogerontology. The journal was established in 1998. The current acting editor-in-chief is Ben Zealle ...
'', on the national board of advisors for
High Point University High Point University is a private university in High Point, North Carolina. It is affiliated with the United Methodist Church. The university was founded as High Point College in 1924, and it became High Point University in October 1991. HPU of ...
and on the
SENS Research Foundation The SENS Research Foundation is a non-profit organization that does research programs and public relations work for the application of regenerative medicine to aging. It was founded in 2009, located in Mountain View, California, USA. The organiza ...
's research advisory board. He is a founding member of the
Tissue Engineering and Regenerative Medicine International Society Tissue Engineering and Regenerative Medicine International Society is an international learned society dedicated to tissue engineering and regenerative medicine Regenerative medicine deals with the "process of replacing, engineering or regenera ...
(TERMIS) from which he received the Lifetime Achievement Award. Atala is the director of the Armed Forces Institute of Regenerative Medicine, a federally funded institute created to apply regenerative medicine.


Biography

Atala was born in
Peru , image_flag = Flag of Peru.svg , image_coat = Escudo nacional del Perú.svg , other_symbol = Great Seal of the State , other_symbol_type = National seal , national_motto = "Firm and Happy f ...
and raised in
Coral Gables, Florida Coral Gables, officially City of Coral Gables, is a city in Miami-Dade County, Florida. The city is located southwest of Downtown Miami. As of the 2020 U.S. census, it had a population of 49,248. Coral Gables is known globally as home to the ...
. Atala attended the
University of Miami The University of Miami (UM, UMiami, Miami, U of M, and The U) is a private research university in Coral Gables, Florida. , the university enrolled 19,096 students in 12 colleges and schools across nearly 350 academic majors and programs, i ...
, and he has an
undergraduate degree An undergraduate degree (also called first degree or simply degree) is a colloquial term for an academic degree earned by a person who has completed undergraduate courses. In the United States, it is usually offered at an institution of higher e ...
in
psychology Psychology is the scientific study of mind and behavior. Psychology includes the study of conscious and unconscious phenomena, including feelings and thoughts. It is an academic discipline of immense scope, crossing the boundaries between ...
. He attended medical school at the
University of Louisville The University of Louisville (UofL) is a public research university in Louisville, Kentucky. It is part of the Kentucky state university system. When founded in 1798, it was the first city-owned public university in the United States and one o ...
, where he also completed his
residency Residency may refer to: * Domicile (law), the act of establishing or maintaining a residence in a given place ** Permanent residency, indefinite residence within a country despite not having citizenship * Residency (medicine), a stage of postgra ...
in urology. He did his
fellow A fellow is a concept whose exact meaning depends on context. In learned or professional societies, it refers to a privileged member who is specially elected in recognition of their work and achievements. Within the context of higher education ...
ship at the
Harvard Medical School Harvard Medical School (HMS) is the graduate medical school of Harvard University and is located in the Longwood Medical Area of Boston, Massachusetts. Founded in 1782, HMS is one of the oldest medical schools in the United States and is consi ...
–affiliated
Boston Children's Hospital Boston Children's Hospital formerly known as Children's Hospital Boston until 2012 is a nationally ranked, freestanding acute care children's hospital located in Boston, Massachusetts, adjacent both to its teaching affiliate, Harvard Medical Scho ...
from 1990 to 1992, where he trained under world-renowned pediatric urologic surgeons Alan Retik and Hardy Hendren.


Career

Atala served as the director of the Laboratory for
Tissue Engineering Tissue engineering is a biomedical engineering discipline that uses a combination of cells, engineering, materials methods, and suitable biochemical and physicochemical factors to restore, maintain, improve, or replace different types of biolog ...
and Cellular Therapeutics at Boston Children's Hospital. His work there involved growing human tissues and organs to replace those damaged by disease or defect. This work became important due to shortages in the organ-donor program. Atala continued his work in tissue engineering and printable organs after moving to
Wake Forest Baptist Medical Center Atrium Health Wake Forest Baptist is an academic medical center and health system located in Winston-Salem, North Carolina, and part of Charlotte-based Atrium Health. It is the largest employer in Forsyth County, with more than 19,220 emplo ...
and the Wake Forest School of Medicine in 2004. Along with
Harvard University Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of high ...
researchers, and as described in the journal ''
Nature Biotechnology ''Nature Biotechnology'' is a monthly peer-reviewed scientific journal published by Nature Portfolio. The chief editor heads an in-house team of editors. The focus of the journal is biotechnology including research results and the commercial busi ...
'', Atala has announced that stem cells with enormous potential can be harvested from the amniotic fluid of pregnant women. These
amniotic stem cells Amniotic stem cells are the mixture of stem cells that can be obtained from the amniotic fluid as well as the amniotic membrane. They can develop into various tissue types including skin, cartilage, cardiac tissue, nerves, muscle, and bone. The cell ...
are
pluripotent Pluripotency: These are the cells that can generate into any of the three Germ layers which imply Endodermal, Mesodermal, and Ectodermal cells except tissues like the placenta. According to Latin terms, Pluripotentia means the ability for many thin ...
, meaning they can be manipulated to differentiate into various types of mature cells that make up nerve, muscle, bone, and other tissues, while avoiding the problem of tumor formation and the ethical concerns associated with
embryonic stem cells Embryonic stem cells (ESCs) are pluripotent stem cells derived from the inner cell mass of a blastocyst, an early-stage pre- implantation embryo. Human embryos reach the blastocyst stage 4–5 days post fertilization, at which time they consist ...
. With respect to the amniotic fluid stem cells ("AFS" cells), Atala has said the following: Atala's work was seized on by opponents of the Embryonic Stem Cell Research Bill (a part of the
100-Hour Plan The 100-Hour Plan was a United States Democratic Party political strategy detailing the actions the party pursued upon assuming leadership of the 110th Congress on January 4, 2007. The strategy was announced before the 2006 midterm elections. ...
of the
Democratic Party Democratic Party most often refers to: *Democratic Party (United States) Democratic Party and similar terms may also refer to: Active parties Africa *Botswana Democratic Party *Democratic Party of Equatorial Guinea *Gabonese Democratic Party *Demo ...
in the
110th United States Congress The 110th United States Congress was a meeting of the legislative branch of the United States federal government, between January 3, 2007, and January 3, 2009, during the last two years of the Presidency of George W. Bush. It was composed of ...
) as a more moral alternative. He wrote a letter saying, ''inter alia'', "Some may be interpreting my research as a substitute for the need to pursue other forms of regenerative medicine therapies, such as those involving embryonic stem cells. I disagree with that assertion."


Awards

Atala has been widely recognized for his scientific contributions. His faculty website lists awards and citations including: * Elected to the Institute of Medicine of the National Academy of Sciences in 2011 * Elected to the
National Academy of Inventors The National Academy of Inventors (NAI) is a US non-profit organization dedicated to encouraging inventors in academia, following the model of the National Academies of the United States. It was founded at the University of South Florida in 2010. ...
as a charter fellow in 2013 * Elected and to the
American Institute for Medical and Biological Engineering The American Institute for Medical and Biological Engineering (AIMBE) is a non-profit organization founded in 1991, and headquartered in Washington. It represents 50,000 medical and biomedical engineers, and academic institutions, private industry, ...
in 2016. * The Christopher Columbus Foundation Award, bestowed on a living American who is currently working on a discovery that will significantly affect society. * The World Technology Award in Health and Medicine, presented to individuals achieving significant, lasting progress in 2011. * The Samuel D. Gross Prize, awarded every five years to a national leading surgical researcher by the Philadelphia Academy of Surgery. * The Barringer Medal from the American Association of Genitourinary Surgeons. * The Gold Cystoscope Award from the
American Urological Association The American Urological Association (AUA) is a professional association in the United States for urology professionals. It has its headquarters at the William P. Didusch Center for Urologic History in Maryland. AUA works with many international o ...
for advances in the field. * The American Ingenuity Award for Life Sciences, awarded by '' Smithsonian'' magazine (2016). * The Innovation Award from the
Society of Manufacturing Engineers SME (previously the Society of Manufacturing Engineers) is a non-profit student and professional association for educating and advancing the manufacturing industry in North America. History SME was founded in January 1932 at the height of the G ...
for the creation of synthetic organs * The Rocovich Gold Medal, awarded to a distinguished scientist who has made a major impact on science * The 2013
Edison Awards Edison Awards is an American company that runs an annual competition honoring excellence in innovation in a broad range of categories. Company The Edison Awards were established by the American Marketing Association in 1987 and has been an in ...
* The 2016 Smithsonian Ingenuity Award * The 2016 ''
R&D Magazine Advantage Business Marketing (ABM) was a private American digital marketing and information services company owned by the venture capital firm Owner Resource Group. The company was founded in 2006 and was based in Rockaway, New Jersey, United Stat ...
'' Innovator of the Year Award for his work with bioprinting *Named
Nature Biotechnology ''Nature Biotechnology'' is a monthly peer-reviewed scientific journal published by Nature Portfolio. The chief editor heads an in-house team of editors. The focus of the journal is biotechnology including research results and the commercial busi ...
as one of the top 10 translational researchers in the world *Life Sciences Intellectual Property Review as one of the top influencers in the life sciences intellectual property field *Named by '' U.S. News & World Report'' as one of 14 Pioneers of Medical Progress in the 21st Century *Named by ''
Scientific American ''Scientific American'', informally abbreviated ''SciAm'' or sometimes ''SA'', is an American popular science magazine. Many famous scientists, including Albert Einstein and Nikola Tesla, have contributed articles to it. In print since 1845, it ...
'' as one of the world's most influential people in biotechnology and as a Medical Treatments Leader of the Year for his contributions to the fields of cell, tissue, and organ regeneration in 2015. *Dr. Atala's work has been listed twice as one of ''
Time Time is the continued sequence of existence and events that occurs in an apparently irreversible succession from the past, through the present, into the future. It is a component quantity of various measurements used to sequence events, ...
'' magazine's top ten medical breakthroughs of the year and once as one of 5 discoveries that will change the future of organ transplantation *''
Discover Discover may refer to: Art, entertainment, and media * ''Discover'' (album), a Cactus Jack album * ''Discover'' (magazine), an American science magazine Businesses and brands * DISCover, the ''Digital Interactive Systems Corporation'' * D ...
'' magazine's top science story of the year in the field of medicine in 2007.


References


External links


The Wake Forest Institute for Regenerative Medicine
* *
Anthony Atala: Growing new organs
(TEDMED 2009) *
Anthony Atala: Printing a human kidney
(TED 2011) * *

Ann Parson, ''
The New York Times ''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid d ...
'', July 11, 2006
Regenerative Medicine: 2012
''
The New Yorker ''The New Yorker'' is an American weekly magazine featuring journalism, commentary, criticism, essays, fiction, satire, cartoons, and poetry. Founded as a weekly in 1925, the magazine is published 47 times annually, with five of these issues ...
'', May 7, 2007
Interview with Dr. A. Atala
NDT Educational * ;Peer-reviewed journals

* ttp://www.uk.sagepub.com/journalsProdDesc.nav?level1=G00&currTree=Subjects&prodId=Journal201913/ Therapeutic Advances in Urology
Tissue-engineered autologous vaginal organs in patients: a pilot cohort study

Stem-cell-based, tissue engineered tracheal replacement in a child: a 2-year follow-up study
{{DEFAULTSORT:Atala, Anthony 1958 births Living people 20th-century American scientists 20th-century biologists 21st-century American scientists 21st-century biologists American people of Lebanese descent Developmental biologists Harvard Medical School alumni Members of the National Academy of Medicine Peruvian emigrants to the United States Peruvian people of Lebanese descent University of Louisville School of Medicine alumni University of Miami alumni Wake Forest University faculty