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Amflora (also known as EH92-527-1) is a genetically modified potato
cultivar A cultivar is a type of cultivated plant that people have selected for desired traits and when propagated retain those traits. Methods used to propagate cultivars include: division, root and stem cuttings, offsets, grafting, tissue culture ...
developed by
BASF Plant Science BASF Plant Science is a subsidiary of BASF in which all plant biotechnology activities are consolidated. The company was founded in 1998 and employs approximately 700 people at 6 different locations worldwide. The headquarters of BASF Plant Scienc ...
. "Amflora"
potato The potato is a starchy food, a tuber of the plant ''Solanum tuberosum'' and is a root vegetable native to the Americas. The plant is a perennial in the nightshade family Solanaceae. Wild potato species can be found from the southern Unit ...
plants produce pure
amylopectin Amylopectin is a water-insoluble polysaccharide and highly branched polymer of α-glucose units found in plants. It is one of the two components of starch, the other being amylose. Plants store starch within specialized organelles called amyloplas ...
starch that is processed to
waxy potato starch Waxy potato starch is a variety of commercially available starch composed almost entirely of amylopectin molecules, extracted from new potato varieties. Standard starch extracted from traditional potato varieties contains both amylose and amylopect ...
. It was approved for industrial applications in the
European Union The European Union (EU) is a supranational political and economic union of member states that are located primarily in Europe. The union has a total area of and an estimated total population of about 447million. The EU has often been de ...
on 2 March 2010 by the
European Commission The European Commission (EC) is the executive of the European Union (EU). It operates as a cabinet government, with 27 members of the Commission (informally known as "Commissioners") headed by a President. It includes an administrative body ...
. In January 2012, the potato was withdrawn from the market in the EU.


History

Originally registered on 5 August 1996, Amflora was developed by
geneticist A geneticist is a biologist or physician who studies genetics, the science of genes, heredity, and variation of organisms. A geneticist can be employed as a scientist or a lecturer. Geneticists may perform general research on genetic processes ...
Lennart Erjefält and
agronomist An agriculturist, agriculturalist, agrologist, or agronomist (abbreviated as agr.), is a professional in the science, practice, and management of agriculture and agribusiness. It is a regulated profession in Canada, India, the Philippines, the ...
Jüri Känno of Svalöf Weibull AB. After the European Commission's approval of the potato, BASF announced it was going to produce Amflora seed starting in April 2010 in Germany's
Western Pomerania Historical Western Pomerania, also called Cispomerania, Fore Pomerania, Front Pomerania or Hither Pomerania (german: Vorpommern), is the western extremity of the historic region of Pomerania forming the southern coast of the Baltic Sea, Weste ...
(20 ha) and Sweden (80 ha). It also announced it was planting 150 ha in the
Czech Republic The Czech Republic, or simply Czechia, is a landlocked country in Central Europe. Historically known as Bohemia, it is bordered by Austria to the south, Germany to the west, Poland to the northeast, and Slovakia to the southeast. The ...
"for commercial aims with an unnamed partner." Due to lack of acceptance of GM crops in Europe, BASF Plant Science decided in January 2012 to stop its commercialization activities in Europe and would no longer sell Amflora there, but it would continue seeking regulatory approval for its products in the Americas and Asia.James Kanter for ''The New York Times''. January 16, 2012
BASF to Stop Selling Genetically Modified Products in Europe
/ref> In 2013, an EU court annulled the approval of BASF's Amflora, saying that the EU Commission broke rules when it approved the potato in 2010.


Biology

Waxy potato varieties produce two main kinds of potato starch,
amylose Amylose is a polysaccharide made of α-D-glucose units, bonded to each other through α(1→4) glycosidic bonds. It is one of the two components of starch, making up approximately 20–30%. Because of its tightly packed helical structure, amylose ...
and
amylopectin Amylopectin is a water-insoluble polysaccharide and highly branched polymer of α-glucose units found in plants. It is one of the two components of starch, the other being amylose. Plants store starch within specialized organelles called amyloplas ...
, the latter of which is most industrially useful. The Amflora potato has been modified to contain
antisense In molecular biology and genetics, the sense of a nucleic acid molecule, particularly of a strand of DNA or RNA, refers to the nature of the roles of the strand and its complement in specifying a sequence of amino acids. Depending on the context ...
RNA against the enzyme that drives synthesis of amylose, namely granule bound starch synthase. This resulting potato almost exclusively produces
amylopectin Amylopectin is a water-insoluble polysaccharide and highly branched polymer of α-glucose units found in plants. It is one of the two components of starch, the other being amylose. Plants store starch within specialized organelles called amyloplas ...
, and thus is more useful for the starch industry.


Industrial applications

Regular potato starch contains two constituent types of molecules: amylopectin (80 percent), which is more useful as a
polymer A polymer (; Greek '' poly-'', "many" + ''-mer'', "part") is a substance or material consisting of very large molecules called macromolecules, composed of many repeating subunits. Due to their broad spectrum of properties, both synthetic a ...
for industry, and
amylose Amylose is a polysaccharide made of α-D-glucose units, bonded to each other through α(1→4) glycosidic bonds. It is one of the two components of starch, making up approximately 20–30%. Because of its tightly packed helical structure, amylose ...
(20 percent) which often creates problems as starch retrogradation, so must be modified with chemical reactions which can be costly.http://www.basf.com/group/corporate/en/function/conversions:/publish/content/products-and-industries/biotechnology/plant-biotechnology/images/BASF_Plant_Science_Amflora.pdf After two decades of research efforts, BASF's biotechnologists using genetic engineering succeeded in creating a potato, named "Amflora", where the gene responsible for the synthesis of amylose had been turned off, thus the potato is unable to synthesize the less desirable amylose. Amflora potatoes would be processed and sold as starch to industries that prefer waxy potato starch with only amylopectin. Amflora is intended only for industrial applications such as papermaking and other technical applications. Europe produces more than two million metric tons of natural potato starch a year, and BASF with its Amflora product hoped to enter into this large market.


Other possible uses

According to ''
The New York Times ''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid d ...
'', BASF has a second application pending for use of Amflora's potato pulp as animal feed.


Political disagreements

Various
environmental organizations An environmental organization is an organization coming out of the conservation or environmental movements that seeks to protect, analyse or monitor the environment against misuse or degradation from human forces. In this sense the environmen ...
, such as Greenpeace, disagreed with the introduction of the Amflora genetically modified potato into the market. The lengthy approval process frustrated some supporters of the potato. A BASF scientist said to ''The New York Times'', "it's hard when you see an innovative product go through the loops again and again. These decisions are not about science but about politics". After the potato was approved, the
European Greens The European Green Party (EGP), also referred to as European Greens, is the European political party that represents national parties from across Europe who share Green values. The European Greens works closely with the Greens–European Free ...
political party and the then Italian agricultural minister
Luca Zaia Luca Zaia (born 27 March 1968) is a Venetian and Venetist politician, who has been President of Veneto since 2010. Prior to that, Zaia was President of the Province of Treviso from 1998 to 2005, Vice President of Veneto from 2005 to 2008 and ...
criticized the approval. The International Peasant Movement La Via Campesina issued a press release on 8 March 2010 also criticizing the decision.


Reactions by Greek politicians

After Amflora's licensing by the European Commission on 2 March 2010, the
Coalition of the Radical Left The Coalition of the Radical Left – Progressive Alliance ( el, Συνασπισμός Ριζοσπαστικής Αριστεράς – Προοδευτική Συμμαχία, Synaspismós Rizospastikís Aristerás – Proodeftikí Simachía), ...
's
Member of Parliament A member of parliament (MP) is the representative in parliament of the people who live in their electoral district. In many countries with bicameral parliaments, this term refers only to members of the lower house since upper house members o ...
for the A Thessalonikis prefecture, Tasos Kouvelis, asked the Greek Minister of Agriculture on 3 March 2010 to declare the production of the potato illegal in
Greece Greece,, or , romanized: ', officially the Hellenic Republic, is a country in Southeast Europe. It is situated on the southern tip of the Balkans, and is located at the crossroads of Europe, Asia, and Africa. Greece shares land borders ...
. On 4 March 2010
Panhellenic Socialist Movement The Panhellenic Socialist Movement ( el, Πανελλήνιο Σοσιαλιστικό Κίνημα, Panellínio Sosialistikó Kínima, ), known mostly by its acronym PASOK, (; , ) is a social-democratic political party in Greece. Until 2012, it ...
's European Member of Parliament Kriton Arsenis submitted a question at Europarl asking about the consequences of Amflora. PASOK's MP
Maria Damanaki Maria Damanaki ( el, Μαρία Δαμανάκη) is a Greek politician, including former president of the Synaspismos party of the left and former state member of the Hellenic Parliament within the Panhellenic Socialist Movement (PASOK). She se ...
accepted the decision of the European Commission, while Greek Agriculture Minister Katerina Batzeli said the production of Amflora will not be allowed in Greece.


Licensing procedure

Amflora could not be sold within the European Union without approval, and its licence could only be issued after voting at the Council of Ministers of the European Union with a 74 percent threshold of support. Two rounds of voting were held, first by experts in December 2006 and then by the agricultural ministers in July 2007, but both failed to reach the 74 percent threshold. Although the voting was by secret ballot, ''The New York Times'' reported that Amflora was supported by the agricultural ministers of
Germany Germany,, officially the Federal Republic of Germany, is a country in Central Europe. It is the second most populous country in Europe after Russia, and the most populous member state of the European Union. Germany is situated betwe ...
and
Belgium Belgium, ; french: Belgique ; german: Belgien officially the Kingdom of Belgium, is a country in Northwestern Europe. The country is bordered by the Netherlands to the north, Germany to the east, Luxembourg to the southeast, France to th ...
, and was opposed by the agricultural ministers of
Italy Italy ( it, Italia ), officially the Italian Republic, ) or the Republic of Italy, is a country in Southern Europe. It is located in the middle of the Mediterranean Sea, and its territory largely coincides with the homonymous geographical ...
,
Ireland Ireland ( ; ga, Éire ; Ulster Scots dialect, Ulster-Scots: ) is an island in the Atlantic Ocean, North Atlantic Ocean, in Northwestern Europe, north-western Europe. It is separated from Great Britain to its east by the North Channel (Grea ...
, and
Austria Austria, , bar, Östareich officially the Republic of Austria, is a country in the southern part of Central Europe, lying in the Eastern Alps. It is a federation of nine states, one of which is the capital, Vienna, the most populous ...
, while the agricultural ministers of
France France (), officially the French Republic ( ), is a country primarily located in Western Europe. It also comprises of overseas regions and territories in the Americas and the Atlantic, Pacific and Indian Oceans. Its metropolitan area ...
and
Bulgaria Bulgaria (; bg, България, Bǎlgariya), officially the Republic of Bulgaria,, ) is a country in Southeast Europe. It is situated on the eastern flank of the Balkans, and is bordered by Romania to the north, Serbia and North Macedo ...
abstained from voting. After a licence was issued on 2 March 2010, BASF announced its intention to ask for approval of more varieties of genetically modified potatoes, such as the "Fortuna" potato.


References


Further reading

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External links

{{Potato cultivars Genetically modified organisms in agriculture Potato cultivars BASF 1996 in biotechnology