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Amersham plc was a manufacturer of
radiopharmaceutical Radiopharmaceuticals, or medicinal radiocompounds, are a group of pharmaceutical drugs containing radioactive isotopes. Radiopharmaceuticals can be used as diagnostic and therapeutic agents. Radiopharmaceuticals emit radiation themselves, which ...
products, to be used in diagnostic and therapeutic
nuclear medicine Nuclear medicine or nucleology is a medical specialty involving the application of radioactive substances in the diagnosis and treatment of disease. Nuclear imaging, in a sense, is " radiology done inside out" because it records radiation emi ...
procedures. The company became
GE Healthcare GE HealthCare is a subsidiary of American multinational conglomerate General Electric incorporated in New York and headquartered in Chicago, Illinois. As of 2017, it is a manufacturer and distributor of diagnostic imaging agents and radiopharma ...
following a takeover in 2003, which was based at the original site in Amersham, Buckinghamshire until 2016, when the headquarters moved to
Chicago (''City in a Garden''); I Will , image_map = , map_caption = Interactive Map of Chicago , coordinates = , coordinates_footnotes = , subdivision_type = Country , subdivision_name ...
.


History

Chilcote House in Little Chalfont near Amersham was first used for extraction of
radium Radium is a chemical element with the symbol Ra and atomic number 88. It is the sixth element in group 2 of the periodic table, also known as the alkaline earth metals. Pure radium is silvery-white, but it readily reacts with nitrogen (rathe ...
from radium concentrates in 1940, under Walter Patrick Grove. Over the next four years over 500
kilograms The kilogram (also kilogramme) is the unit of mass in the International System of Units (SI), having the unit symbol kg. It is a widely used measure in science, engineering and commerce worldwide, and is often simply called a kilo colloquially ...
of
radium bromide Radium bromide is the bromide salt of radium, with the formula RaBr2. It is produced during the process of separating radium from uranium ore. This inorganic compound was discovered by Pierre and Marie Curie in 1898, and the discovery sparked a hug ...
was produced, to be used to make luminous dials and instruments. In 1946 the facility was taken over by the Ministry of Supply and it became known as the “national centre for the processing and distribution of radium, radon and artificial radioactive substances for scientific, medical and industrial purposes”. With a new focus on healthcare and industrial applications, the site was expanded and by 1949 when the name changed to "The Radiochemical Centre (TRC), Amersham", production included radium gas capsules for cancer treatment and carbon-14. The following year it became an outstation of the Atomic Energy Research Establishment (UKAERA) at Harwell, processing materials produced in its reactors. By the 1960s, TRC had over 1000 catalogue items, using over 100 isotopes and exporting to 60 countries. A
cyclotron A cyclotron is a type of particle accelerator invented by Ernest O. Lawrence in 1929–1930 at the University of California, Berkeley, and patented in 1932. Lawrence, Ernest O. ''Method and apparatus for the acceleration of ions'', filed: Jan ...
was installed, the first for medical isotope production. With restructuring of the UKAERA in 1971, TRC became a
limited company In a limited company, the liability of members or subscribers of the company is limited to what they have invested or guaranteed to the company. Limited companies may be limited by shares or by guarantee. In a company limited by shares, the lia ...
. By this time TRC had several international subsidiaries for example Amersham Buchler GmbH & Co. KG a Joint Venture with the Quinine Factory Buchler GmbH in Braunschweig (West-Germany). In 1976 work began on a second production site in
Cardiff Cardiff (; cy, Caerdydd ) is the capital and largest city of Wales. It forms a principal area, officially known as the City and County of Cardiff ( cy, Dinas a Sir Caerdydd, links=no), and the city is the eleventh-largest in the United Kingd ...
. The Radiochemical Centre Limited became Amersham International Limited in 1981 and was the first company to be privatised by the Thatcher Government in 1982 under the new name Amersham International plc. It was the first privatisation in which the government sold 100% of its shares in a company. The offer was 24.6 times subscribed, meaning the share price rose from 142p per share to 188p per share by closing on the first day. The government retained a special share, allowing the veto of any outsourcing attempts, until it was redeemed in 1988. In the early 1990s, the in-vitro diagnostic assay business was
divested In finance and economics, divestment or divestiture is the reduction of some kind of asset for financial, ethical, or political objectives or sale of an existing business by a firm. A divestment is the opposite of an investment. Divestiture is a ...
to a joint venture with Eastman Kodak called Amerlite Diagnostics Ltd, this was later wholly acquired by Eastman Kodak and renamed Kodak Clinical Diagnostics Ltd. This business was sold by Kodak to Johnson & Johnson and became known as Johnson & Johnson Clinical Diagnostics Ltd. The business is now called Ortho-Clinical Diagnostics Ltd. In 1997
Pharmacia Pharmacia was a pharmaceutical and biotechnological company in Sweden that merged with the American pharmaceutical company Upjohn in 1995. History Pharmacia company was founded in 1911 in Stockholm, Sweden by pharmacist Gustav Felix Grönfeldt ...
Biotech ( Sweden), then owned by
Pharmacia & Upjohn Pharmacia & Upjohn was a global pharmaceutical company formed by the merger of Sweden-based Pharmacia AB and the American company Upjohn in 1995. Today the remainder of the company is owned by Pfizer. In 1997, Pharmacia & Upjohn sold several bra ...
, was fused with Amersham Life Science and renamed Amersham Pharmacia Biotech. The Pharmacia name of this subsidiary was later dropped when Pharmacia & Upjohn sold its share of the company to Amersham plc, and changed its name to Amersham Biosciences in 2001. In 1997, Amersham merged with
Nycomed Nycomed is a Swiss pharmaceutical company. Nycomed was acquired by Takeda Pharmaceuticals in September 2011. Production was located in Norway, Denmark, Poland, Austria, Belgium, Germany, Estonia, India, Mexico, Brazil and Argentina. Head office i ...
(
Norway Norway, officially the Kingdom of Norway, is a Nordic country in Northern Europe, the mainland territory of which comprises the western and northernmost portion of the Scandinavian Peninsula. The remote Arctic island of Jan Mayen and the ...
) to form ''Nycomed Amersham plc''. In 1999, the Nycomed Pharma subsidiary was sold to
Nordic Capital Nordic Capital private equity funds focus on investments primarily in Northern Europe. Nordic Capital invests in selective industries with a particular focus on Healthcare, Tech & Payments and Financial Services. In addition selective investments ...
, and in 2001 ''Nycomed Amersham plc'' was renamed to ''Amersham plc''. In 2004, Amersham was acquired by the American firm
General Electric General Electric Company (GE) is an American multinational conglomerate founded in 1892, and incorporated in New York state and headquartered in Boston. The company operated in sectors including healthcare, aviation, power, renewable en ...
(GE) and incorporated into the
GE Healthcare GE HealthCare is a subsidiary of American multinational conglomerate General Electric incorporated in New York and headquartered in Chicago, Illinois. As of 2017, it is a manufacturer and distributor of diagnostic imaging agents and radiopharma ...
business segment. In 2005 the
Royal Society of Chemistry The Royal Society of Chemistry (RSC) is a learned society (professional association) in the United Kingdom with the goal of "advancing the chemical sciences". It was formed in 1980 from the amalgamation of the Chemical Society, the Royal Instit ...
named the former Amersham Laboratories, known as the Grove Centre under GE, as an historic chemical landmark for its "achievements in the fields of industrial and medical applications" over the past six decades.


Operations

GE Healthcare GE HealthCare is a subsidiary of American multinational conglomerate General Electric incorporated in New York and headquartered in Chicago, Illinois. As of 2017, it is a manufacturer and distributor of diagnostic imaging agents and radiopharma ...
has a UK office in Chalfont St. Giles, near Amersham. In 2018 part of the company's Cardiff site was sold for redevelopment as operations consolidated into a smaller area. Amersham's former business segments became
GE Healthcare GE HealthCare is a subsidiary of American multinational conglomerate General Electric incorporated in New York and headquartered in Chicago, Illinois. As of 2017, it is a manufacturer and distributor of diagnostic imaging agents and radiopharma ...
Medical Diagnostics and GE Healthcare Life Sciences. In 2020 GE Healthcare Life Sciences was acquired by
Danaher Corporation Danaher Corporation is an American globally diversified conglomerate with its headquarters in Washington, D.C. The company designs, manufactures, and markets professional, medical, industrial, and commercial products and services. The company' ...
and renamed Cytiva.


See also

*
Pharmaceutical industry in the United Kingdom The pharmaceutical industry in the United Kingdom directly employs around 73,000 people and in 2007 contributed £8.4 billion to the UK's GDP and invested a total of £3.9 billion in research and development. In 2007 exports of pharmaceutical prod ...


References


External links


2004 archive copy of Amersham plc website
{{Authority control Amersham British companies established in 1946 Pharmaceutical companies of the United Kingdom Companies formerly listed on the London Stock Exchange Companies based in Buckinghamshire 1946 establishments in England Pharmaceutical companies established in 1946