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''Artemisia absinthium'' (wormwood, grand wormwood, absinthe, absinthium, absinthe wormwood, mugwort, wermout, wermud, wormit, wormod) is a species of ''
Artemisia Artemisia may refer to: People * Artemisia I of Caria (fl. 480 BC), queen of Halicarnassus under the First Persian Empire, naval commander during the second Persian invasion of Greece * Artemisia II of Caria (died 350 BC), queen of Caria under th ...
'',
native Native may refer to: People * Jus soli, citizenship by right of birth * Indigenous peoples, peoples with a set of specific rights based on their historical ties to a particular territory ** Native Americans (disambiguation) In arts and entert ...
to
temperate In geography, the temperate climates of Earth occur in the middle latitudes (23.5° to 66.5° N/S of Equator), which span between the tropics and the polar regions of Earth. These zones generally have wider temperature ranges throughout ...
regions of
Eurasia Eurasia (, ) is the largest continental area on Earth, comprising all of Europe and Asia. Primarily in the Northern and Eastern Hemispheres, it spans from the British Isles and the Iberian Peninsula in the west to the Japanese archipelago ...
and
North Africa North Africa, or Northern Africa is a region encompassing the northern portion of the African continent. There is no singularly accepted scope for the region, and it is sometimes defined as stretching from the Atlantic shores of Mauritania in ...
, and widely naturalized in
Canada Canada is a country in North America. Its ten provinces and three territories extend from the Atlantic Ocean to the Pacific Ocean and northward into the Arctic Ocean, covering over , making it the world's second-largest country by tot ...
and the northern
United States The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 states, a federal district, five major unincorporated territori ...
. It is grown as an
ornamental plant Ornamental plants or garden plants are plants that are primarily grown for their beauty but also for qualities such as scent or how they shape physical space. Many flowering plants and garden varieties tend to be specially bred cultivars that ...
and is used as an ingredient in the spirit absinthe and some other alcoholic beverages.


Etymology

''Artemisia'' comes from
Ancient Greek Ancient Greek includes the forms of the Greek language used in ancient Greece and the ancient world from around 1500 BC to 300 BC. It is often roughly divided into the following periods: Mycenaean Greek (), Dark Ages (), the Archaic p ...
ἀρτεμισία, from Ἄρτεμις (
Artemis In ancient Greek mythology and religion, Artemis (; grc-gre, Ἄρτεμις) is the goddess of the hunt, the wilderness, wild animals, nature, vegetation, childbirth, care of children, and chastity. She was heavily identified wit ...
). In
Hellenistic In Classical antiquity, the Hellenistic period covers the time in Mediterranean history after Classical Greece, between the death of Alexander the Great in 323 BC and the emergence of the Roman Empire, as signified by the Battle of Actium in ...
culture, Artemis was a goddess of the hunt, and protector of the forest and children. The name ''absinthum'' comes from the Ancient Greek ἀψίνθιον, meaning the same. An alternative derivation is that the genus was named after Queen Artemisia, who was the wife and sister of
Mausolus Mausolus ( grc, Μαύσωλος or , xcr, ���𐊠���𐊸𐊫𐊦 ''Mauśoλ'') was a ruler of Caria (377–353 BCE) and a satrap of the Achaemenid Empire. He enjoyed the status of king or dynast by virtue of the powerful position created by ...
, ruler of Caria. The word "wormwood" may come from
Middle English Middle English (abbreviated to ME) is a form of the English language that was spoken after the Norman conquest of 1066, until the late 15th century. The English language underwent distinct variations and developments following the Old English ...
''wormwode'' or ''wermode''.
Webster's ''Webster's Dictionary'' is any of the English language dictionaries edited in the early 19th century by American lexicographer Noah Webster (1758–1843), as well as numerous related or unrelated dictionaries that have adopted the Webster's ...
Third New International Dictionary attributes the etymology to
Old English Old English (, ), or Anglo-Saxon, is the earliest recorded form of the English language, spoken in England and southern and eastern Scotland in the early Middle Ages. It was brought to Great Britain by Anglo-Saxon settlers in the mid-5th c ...
''wermōd'' (compare with German ''Wermut'' and the derived drink vermouth), which the
OED The ''Oxford English Dictionary'' (''OED'') is the first and foundational historical dictionary of the English language, published by Oxford University Press (OUP). It traces the historical development of the English language, providing a co ...
(''s.v.'') marks as "of obscure origin". Some sources state the word "wormwood" comes from the ancient use of the plant as
antihelminthic Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. They may ...
(expelling parasitic worms from the body by either stunning or killing them), documented in ''Natural History'' by Pliny (first century AD).


Description

''A. absinthium'' is a herbaceous
perennial plant A perennial plant or simply perennial is a plant that lives more than two years. The term ('' per-'' + '' -ennial'', "through the years") is often used to differentiate a plant from shorter-lived annuals and biennials. The term is also wide ...
with fibrous roots. The stems are straight, growing to (and rarely over ) tall, grooved, branched, and silvery-green. Leaves are spirally arranged, greenish-grey colored above, white below, covered with silky silvery-white
trichome Trichomes (); ) are fine outgrowths or appendages on plants, algae, lichens, and certain protists. They are of diverse structure and function. Examples are hairs, glandular hairs, scales, and papillae. A covering of any kind of hair on a p ...
s, and bearing minute oil-producing glands. The
basal leaves A leaf ( : leaves) is any of the principal appendages of a vascular plant stem, usually borne laterally aboveground and specialized for photosynthesis. Leaves are collectively called foliage, as in "autumn foliage", while the leaves, st ...
are up to long, bi- to tripinnate with long petioles, with the cauline leaves (those on the stem) smaller, long, less divided, and with short petioles. The uppermost leaves can be both simple and sessile (without a petiole).
Flower A flower, sometimes known as a bloom or blossom, is the reproductive structure found in flowering plants (plants of the division Angiospermae). The biological function of a flower is to facilitate reproduction, usually by providing a mechani ...
s are pale yellow, tubular, and clustered in spherical bent-down heads (capitula), which are in turn clustered in leafy and branched panicles. Flowering occurs from early summer to early autumn; pollination is
anemophilous Anemophily or wind pollination is a form of pollination whereby pollen is distributed by wind. Almost all gymnosperms are anemophilous, as are many plants in the order Poales, including grasses, sedges, and rushes. Other common anemophilous plan ...
. The
fruit In botany, a fruit is the seed-bearing structure in flowering plants that is formed from the ovary after flowering. Fruits are the means by which flowering plants (also known as angiosperms) disseminate their seeds. Edible fruits in particu ...
is a small achene. Seed dispersal occurs by gravity. ''A. absinthium'' grows naturally on uncultivated arid ground, on rocky slopes, and at the edge of footpaths and fields. Although once relatively common, it is becoming increasingly rare in the UK, where it has recently been suggested to be an
archaeophyte An archaeophyte is a plant species which is non-native to a geographical region, but which was an introduced species in "ancient" times, rather than being a modern introduction. Those arriving after are called neophytes. The cut-off date is usua ...
rather than a true native.


Cultivation

The plant can easily be cultivated in dry soil. It should be planted under bright exposure in fertile, midweight soil. It prefers soil rich in
nitrogen Nitrogen is the chemical element with the symbol N and atomic number 7. Nitrogen is a nonmetal and the lightest member of group 15 of the periodic table, often called the pnictogens. It is a common element in the universe, estimated at se ...
, and can be propagated by ripened cuttings taken in spring or autumn in temperate climates, or by seeds in nursery beds. Growing the plant with others tends to stunt their growth; accordingly, it is not considered to be a good companion plant. ''A. absinthium'' also self-seeds generously. It is
naturalised Naturalization (or naturalisation) is the legal act or process by which a non-citizen of a country may acquire citizenship or nationality of that country. It may be done automatically by a statute, i.e., without any effort on the part of the i ...
in some areas away from its native range, including much of North America and Kashmir Valley of India.Shafi et al., 2012 This plant, and its
cultivar A cultivar is a type of cultivated plant that people have selected for desired traits and when propagated retain those traits. Methods used to propagate cultivars include: division, root and stem cuttings, offsets, grafting, tissue culture ...
s 'Lambrook Mist' and 'Lambrook Silver' have gained the
Royal Horticultural Society The Royal Horticultural Society (RHS), founded in 1804 as the Horticultural Society of London, is the UK's leading gardening charity. The RHS promotes horticulture through its five gardens at Wisley (Surrey), Hyde Hall (Essex), Harlow Carr (Nor ...
's Award of Garden Merit. These two short cultivars are very similar and more silver than typical British absinthium material and probably derive from southern Europe. 'Lambrook Silver' is the earliest of these cultivars, having been selected in the late 1950s by Margery Fish, who developed the garden at East Lambrook Manor. 'Lambrook Mist' was selected about 30 years later by Andrew Norton, a subsequent owner of the garden. Both gained their Awards of Garden Merit during the RHS Artemisia Trial 1991–3. Cultivar 'Silver Ghost' is a taller, silver plant, which flowers much later (August–September) than typical absinthium (June–July) in UK, so holds its silver appearance for longer. This and a more feathery-leaved cultivar 'Persian Lace' were selected by National Collection Holder John Twibell in the 1990s.


Constituents

Wormwood herb contains bitter substances from the group of
sesquiterpene lactone Sesquiterpene lactones (SLs) are a class of sesquiterpenoids that contain a lactone ring. They are most often found in plants of the family Asteraceae (daisies, asters). Other plant families with SLs are Umbelliferae (celery, parsley, carrots) an ...
s; absinthin, at 0.20 to 0.28%, is the main component of these bitter substances. Essential oils make up 0.2 to 0.8% and contain (-) - thujone, (+) - isothujone, thujyl alcohol and its esters,
chamazulene Chamazulene is an aromatic chemical compound with the molecular formula C14H16 found in a variety of plants including in chamomile (''Matricaria chamomilla''), wormwood (''Artemisia absinthium''), and yarrow (''Achillea millefolium''). It is a b ...
and other mono- and sesquiterpenes. In Bailen et al 2013 and Gonzalez-Coloma et al 2013 the Gonzalez-Coloma group discovered a chemotype that does not produce β-thujone but does contain
terpenoid The terpenoids, also known as isoprenoids, are a class of naturally occurring organic chemicals derived from the 5-carbon compound isoprene and its derivatives called terpenes, diterpenes, etc. While sometimes used interchangeably with "terpenes" ...
s not seen elsewhere.


Uses

It is an ingredient in the spirit absinthe, and is used for flavouring in some other
spirits Spirit or spirits may refer to: Liquor and other volatile liquids * Spirits, a.k.a. liquor, distilled alcoholic drinks * Spirit or tincture, an extract of plant or animal material dissolved in ethanol * Volatile (especially flammable) liquids, ...
and
wine Wine is an alcoholic drink typically made from fermented grapes. Yeast consumes the sugar in the grapes and converts it to ethanol and carbon dioxide, releasing heat in the process. Different varieties of grapes and strains of yeasts are m ...
s, including
bitters Bitters (plural also ''bitters'') is traditionally an alcoholic preparation flavored with botanical matter for a bitter or bittersweet flavor. Originally, numerous longstanding brands of bitters were developed as patent medicines, but now ar ...
,
bäsk Bäsk is a Swedish-style liquor flavored with wormwood ("malört" in Swedish) or anise. Sweden is one of the few countries that has never banned absinthe or other wormwood-flavored liquors. ''Bäsk'' is an old alternative spelling of the wo ...
,
vermouth Vermouth (, ) is an aromatized fortified wine, flavoured with various botanicals (roots, barks, flowers, seeds, herbs, and spices) and sometimes colored. The modern versions of the beverage were first produced in the mid- to late 18th centur ...
, and
pelinkovac Pelinkovac is a bitter liqueur based on wormwood ( Croatian and Slovenian: ''pelen'' or ''pelin''), popular in Croatia, Serbia, Montenegro, Bosnia and Herzegovina, North Macedonia, Bulgaria as well as in Slovenia, where it is known as pelinkove ...
. As medicine, it is used for
dyspepsia Indigestion, also known as dyspepsia or upset stomach, is a condition of impaired digestion. Symptoms may include upper abdominal fullness, heartburn, nausea, belching, or upper abdominal pain. People may also experience feeling full earlier ...
, as a bitter to counteract poor appetite, for various infectious diseases, Crohn's disease, and
IgA nephropathy IgA nephropathy (IgAN), also known as Berger's disease () (and variations), or synpharyngitic glomerulonephritis, is a disease of the kidney (or nephropathy) and the immune system; specifically it is a form of glomerulonephritis or an inflammati ...
. In the Middle Ages, wormwood was used to spice mead, and in Morocco, it is used with tea, called ''sheeba''. Wormwood was traditionally relatively common as a bittering spice in farmhouse brewing in
Denmark ) , song = ( en, "King Christian stood by the lofty mast") , song_type = National and royal anthem , image_map = EU-Denmark.svg , map_caption = , subdivision_type = Sovereign state , subdivision_name = Kingdom of Denmark , establish ...
, and to some extent
Estonia Estonia, formally the Republic of Estonia, is a country by the Baltic Sea in Northern Europe. It is bordered to the north by the Gulf of Finland across from Finland, to the west by the sea across from Sweden, to the south by Latvia, a ...
. In 18th-century England, wormwood was sometimes used instead of hops in
beer Beer is one of the oldest and the most widely consumed type of alcoholic drink in the world, and the third most popular drink overall after water and tea. It is produced by the brewing and fermentation of starches, mainly derived from ce ...
. Wormwood clippings and cuttings are added to chicken nesting boxes to repel lice, mites, and fleas. Bailen ''et al.'' 2013 and Gonzalez-Coloma ''et al.'' 2013 find the unique terpenoids of the Gonzalez-Coloma chemotype make this strain especially promising for
insect control Pest control is the regulation or management of a species defined as a pest; any animal, plant or fungus that impacts adversely on human activities or environment. The human response depends on the importance of the damage done and will range ...
. a company named EcoflorAgro is investing heavily into increasing the planted area of this strain, hoping to commercialize it to a degree attempted but never achieved due to unreliable supply for other
botanical insecticide A Biopesticide is a biological substance or organism that damages, kills, or repels organisms seens as pests. Biological pest management intervention involves predatory, parasitic, or chemical relationships. They are obtained from organisms inclu ...
s before.


Toxicity

Most chemotypes of ''A. absinthium'' contain (−)-α- and/or (+)-β-
thujone Thujone () is a ketone and a monoterpene that occurs predominantly in two diastereomeric (epimeric) forms: (−)-α-thujone and (+)-β-thujone. Though it is best known as a chemical compound in the spirit absinthe, it is unlikely to be responsib ...
, though some do not. (−)-α-Thujone by itself is a GABA receptor antagonist that can cause
convulsions A convulsion is a medical condition where the body muscles contract and relax rapidly and repeatedly, resulting in uncontrolled shaking. Because epileptic seizures typically include convulsions, the term ''convulsion'' is sometimes used as a s ...
and death when administered in large amounts to animals and humans. However, there is only one case of documented toxicity of wormwood involving a 31-year-old man who drank 10 mL of steam-distilled volatile oil of wormwood, wrongly believing it was absinthe liqueur. Medicinal extracts of wormwood have not been shown to cause seizure or other adverse effects at usual doses. Thujones have not been shown to be the cause of excessive doses' toxicity for any kind of wormwood extracts, including absinthe.


Folk names

''A. absinthium'' has many folk names: ''absint-alsem'' (Dutch), ''absinth, absinthe, absinthium vulgate, Absinthkraut, agenjo, ajenjo común, artenheil, assenzio vero'' (Italian), ''Bitterer Beifuß, botrys, eberreis, echter Wermut, gengibre verde'' (Spanish)'', Heilbitter,'' green muse,'' grüne Fee, la fée verte, Magenkraut, Shih'' (Arabic),'' Schweizertee, wermod ''(Saxon),'' wor-mod ''(Old English), ”malört” (Swedish) and others.


Cultural history

In the Bible, the
Book of Revelation The Book of Revelation is the final book of the New Testament (and consequently the final book of the Christian Bible). Its title is derived from the first word of the Koine Greek text: , meaning "unveiling" or "revelation". The Book of ...
tells of a star named Wormwood that plummets to Earth and turns a third of the rivers and fountains of waters bitter.
Nicholas Culpeper Nicholas Culpeper (18 October 1616 – 10 January 1654) was an English botanist, herbalist, physician and astrologer.Patrick Curry: "Culpeper, Nicholas (1616–1654)", ''Oxford Dictionary of National Biography'' (Oxford, UK: OUP, 2004) His bo ...
insisted that wormwood was the key to understanding his 1651 book ''The English Physitian''.
Richard Mabey Richard Thomas Mabey (born 20 February 1941) is a writer and broadcaster, chiefly on the relations between nature and culture. Education Mabey was educated at three independent schools, all in Berkhamsted, Hertfordshire. The first was at Roth ...
describes Culpeper's entry on this bitter-tasting plant as "stream-of-consciousness" and "unlike anything else in the herbal", and states that it reads "like the ramblings of a drunk". Culpeper biographer
Benjamin Woolley Benjamin Woolley is an author, media journalist and television presenter. In 2018, he published ''The King's Assassin'.'' Biography Woolley studied Philosophy & Politics at Durham University, graduating in 1979. Woolley currently teaches Engli ...
suggests the piece may be an allegory about bitterness, as Culpeper had spent his life fighting the Establishment, and had been imprisoned and seriously wounded in battle as a result. William Shakespeare referred to wormwood in Romeo and Juliet: Act 1, Scene 3. Juliet's childhood nurse said, "For I had then laid wormwood to my dug" meaning that the nurse had weaned Juliet, then aged three, by using the bitter taste of wormwood on her nipple. John Locke, in his 1689 book titled ''
An Essay Concerning Human Understanding ''An Essay Concerning Human Understanding'' is a work by John Locke concerning the foundation of human knowledge and understanding. It first appeared in 1689 (although dated 1690) with the printed title ''An Essay Concerning Humane Understan ...
'', used wormwood as an example of bitterness, writing, "For a child knows as certainly before it can speak the difference between the ideas of sweet and bitter (i.e. that sweet is not bitter), as it knows afterwards (when it comes to speak) that wormwood and sugarplums are not the same thing."
Edwin Arlington Robinson Edwin Arlington Robinson (December 22, 1869 – April 6, 1935) was an American poet and playwright. Robinson won the Pulitzer Prize for Poetry on three occasions and was nominated for the Nobel Prize in Literature four times. Early life Robin ...
relates in a poem how Cliff Klingenhagen gave a guest a glass of wine while drinking a glass of wormwood himself. He concludes, "I have spent / Long time a-wondering when I shall be / As happy as Cliff Klingenhagen is."


References


External links


Biodiversity Heritage Library bibliography
for ''Artemisia absinthium''
Erowid Wormwood Vault
information on the use and preparation of wormwood, along with user experiences. * European Medicines Agency (4 March 2020)
European Union herbal monograph on ''Artemisia absinthium'' L., herba
Amsterdam {{Authority control
absinthium ''Artemisia absinthium'' (wormwood, grand wormwood, absinthe, absinthium, absinthe wormwood, mugwort, wermout, wermud, wormit, wormod) is a species of '' Artemisia'', native to temperate regions of Eurasia and North Africa, and widely naturalize ...
Absinthe Medicinal plants of Africa Medicinal plants of Asia Medicinal plants of Europe Plants described in 1753 Edible plants Taxa named by Carl Linnaeus