Acyl-homoserine-lactone synthase () is an
enzyme with
systematic name ''acyl-(acyl-carrier protein):S-adenosyl-L-methionine acyltranserase (lactone-forming, methylthioadenosine-releasing)''.
This enzyme
catalyses the following
chemical reaction
: acyl-
cyl-carrier protein+
S-adenosyl-L-methionine cyl-carrier protein+ S-methyl-5'-thioadenosine + N-acyl-L-homoserine lactone
Acyl-homoserine lactones (AHLs) are produced by a number of bacterial species and are used by them to regulate the expression of
virulence genes in a process known as
quorum-sensing
In biology, quorum sensing or quorum signalling (QS) is the ability to detect and respond to cell population density by gene regulation. As one example, QS enables bacteria to restrict the expression of specific genes to the high cell densities at ...
.
Alternate names
''acyl-homoserine lactone synthase'', ''acyl homoserine lactone synthase'', ''acyl-homoserinelactone synthase'', ''acylhomoserine lactone synthase'', ''AHL synthase'', ''AHS'', ''AHSL synthase'', ''AhyI'', ''AinS'', ''AinS protein'', ''autoinducer synthase'', ''autoinducer synthesis protein rhlI'', ''EsaI'', ''ExpISCC1'', ''ExpISCC3065'', ''LasI'', ''LasR'', ''LuxI'', ''LuxI protein'', ''LuxM'', ''N-acyl homoserine lactone synthase'', ''RhlI'', ''YspI'', ''acyl-
cyl carrier proteinS-adenosyl-L-methionine acyltranserase (lactone-forming, methylthioadenosine-releasing)''
References
External links
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EC 2.3.1