Atrolysin E (, ''Crotalus atrox metalloendopeptidase e'', ''hemorrhagic toxin e'') is an

enzyme Enzymes () are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products ...

. This enzyme catalyses the following

chemical reaction A chemical reaction is a process that leads to the IUPAC nomenclature for organic transformations, chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the pos ...

: Cleavage of Asn³-Gln, Ser⁹-His and Ala¹⁴-Leu bonds in insulin B chain and Tyr¹⁴-Gln and Thr⁸-Ser in A chain. Cleaves type IV collagen at Ala⁷³-Gln in alpha1(IV) and at Gly⁷-Leu in alpha2(IV) This

endopeptidase Endopeptidase or endoproteinase are proteolytic peptidases that break peptide bonds of nonterminal amino acids (i.e. within the molecule), in contrast to exopeptidases, which break peptide bonds from end-pieces of terminal amino acids. For this ...

is present in the

venom Venom or zootoxin is a type of toxin produced by an animal that is actively delivered through a wound by means of a bite, sting, or similar action. The toxin is delivered through a specially evolved ''venom apparatus'', such as fangs or a st ...

of the

western diamondback rattlesnake The western diamondback rattlesnake or Texas diamond-backWright AH, Wright AA. (1957). ''Handbook of Snakes''. Comstock Publishing Associates. (7th printing, 1985). . (''Crotalus atrox'') is a rattlesnake species and member of the viper family, ...

(''

Crotalus atrox The western diamondback rattlesnake or Texas diamond-backWright AH, Wright AA. (1957). ''Handbook of Snakes''. Comstock Publishing Associates. (7th printing, 1985). . (''Crotalus atrox'') is a rattlesnake species and member of the viper family, ...

'').

References

External links

* {{Portal bar, Biology, border=no EC 3.4.24