Asporin is a
protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...
that in humans is encoded by the ''ASPN''
gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a ba ...
.
Function
ASPN belongs to a family of
leucine-rich repeat (LRR) proteins associated with the cartilage matrix. The name asporin reflects the unique
aspartate-rich N terminus and the overall similarity to
decorin
Decorin is a protein that in humans is encoded by the ''DCN'' gene.
Decorin is a proteoglycan that is on average 90 - 140 kilodaltons (kDa) in molecular weight. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a ...
(MIM 125255) (Lorenzo et al., 2001).
References
External links
*
Further reading
*
*
*
*
*
*
*
*
*
*
*
*
{{gene-9-stub
Extracellular matrix proteins
LRR proteins
Proteoglycans