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Artificial ventilation (also called artificial respiration) is a means of assisting or stimulating
respiration Respiration may refer to: Biology * Cellular respiration, the process in which nutrients are converted into useful energy in a cell ** Anaerobic respiration, cellular respiration without oxygen ** Maintenance respiration, the amount of cellul ...
, a metabolic process referring to the overall exchange of gases in the body by pulmonary ventilation, external respiration, and internal respiration. It may take the form of manually providing air for a person who is not
breath Breathing (or ventilation) is the process of moving air into and from the lungs to facilitate gas exchange with the internal environment, mostly to flush out carbon dioxide and bring in oxygen. All aerobic creatures need oxygen for cellular ...
ing or is not making sufficient respiratory effort, or it may be
mechanical ventilation Mechanical ventilation, assisted ventilation or intermittent mandatory ventilation (IMV), is the medical term for using a machine called a ventilator to fully or partially provide artificial ventilation. Mechanical ventilation helps move air ...
involving the use of a
mechanical ventilator A ventilator is a piece of medical technology that provides mechanical ventilation by moving breathable air into and out of the lungs, to deliver breaths to a patient who is physically unable to breathe, or breathing insufficiently. Ventilators ...
to move air in and out of the lungs when an individual is unable to breathe on their own, for example during
surgery Surgery ''cheirourgikē'' (composed of χείρ, "hand", and ἔργον, "work"), via la, chirurgiae, meaning "hand work". is a medical specialty that uses operative manual and instrumental techniques on a person to investigate or treat a pat ...
with
general anesthesia General anaesthesia (UK) or general anesthesia (US) is a medically induced loss of consciousness that renders the patient unarousable even with painful stimuli. This effect is achieved by administering either intravenous or inhalational general ...
or when an individual is in a
coma A coma is a deep state of prolonged unconsciousness in which a person cannot be awakened, fails to respond normally to painful stimuli, light, or sound, lacks a normal wake-sleep cycle and does not initiate voluntary actions. Coma patients exhi ...
or
trauma Trauma most often refers to: * Major trauma, in physical medicine, severe physical injury caused by an external source * Psychological trauma, a type of damage to the psyche that occurs as a result of a severely distressing event *Traumatic i ...
.


Types


Manual methods

Pulmonary ventilation (and hence external parts of respiration) is achieved through manual insufflation of the lungs either by the rescuer blowing into the patient's lungs (
mouth-to-mouth resuscitation Mouth-to-mouth resuscitation, a form of artificial ventilation, is the act of assisting or stimulating respiration in which a rescuer presses their mouth against that of the victim and blows air into the person's lungs. Artificial respiration ta ...
), or by using a mechanical device to do so. This method of insufflation has been proved more effective than methods which involve mechanical manipulation of the patient's chest or arms, such as the
Silvester method Cardiopulmonary resuscitation (CPR) is an emergency procedure consisting of chest compressions often combined with artificial ventilation in an effort to manually preserve intact brain function until further measures are taken to restore spon ...
. Mouth-to-mouth resuscitation is also part of
cardiopulmonary resuscitation Cardiopulmonary resuscitation (CPR) is an emergency procedure consisting of chest compressions often combined with artificial ventilation in an effort to manually preserve intact brain function until further measures are taken to restore spont ...
(CPR) making it an essential skill for
first aid First aid is the first and immediate assistance given to any person with either a minor or serious illness or injury, with care provided to preserve life, prevent the condition from worsening, or to promote recovery. It includes initial in ...
. In some situations, mouth to mouth is also performed separately, for instance in near-
drowning Drowning is a type of suffocation induced by the submersion of the mouth and nose in a liquid. Most instances of fatal drowning occur alone or in situations where others present are either unaware of the victim's situation or unable to offer a ...
and
opiate An opiate, in classical pharmacology, is a substance derived from opium. In more modern usage, the term ''opioid'' is used to designate all substances, both natural and synthetic, that bind to opioid receptors in the brain (including antagonis ...
overdoses. The performance of mouth to mouth in its own is now limited in most protocols to
health professional A health professional, healthcare professional, or healthcare worker (sometimes abbreviated HCW) is a provider of health care treatment and advice based on formal training and experience. The field includes those who work as a nurse, physician (suc ...
s, whereas lay first aiders are advised to undertake full CPR in any case where the patient is not breathing sufficiently.


Mechanical ventilation

Mechanical ventilation is a method to mechanically assist or replace spontaneous
breathing Breathing (or ventilation) is the process of moving air into and from the lungs to facilitate gas exchange with the internal environment, mostly to flush out carbon dioxide and bring in oxygen. All aerobic creatures need oxygen for cellular ...
. This may involve a machine called a
ventilator A ventilator is a piece of medical technology that provides mechanical ventilation by moving breathable air into and out of the lungs, to deliver breaths to a patient who is physically unable to breathe, or breathing insufficiently. Ventilators ...
or the breathing may be assisted by a registered nurse,
physician A physician (American English), medical practitioner (Commonwealth English), medical doctor, or simply doctor, is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through th ...
,
physician assistant A physician assistant or physician associate (PA) is a type of Mid-level practitioner, mid-level health care provider. In North America PAs may diagnose illnesses, develop and manage treatment plans, prescribe medications, and may serve as a pri ...
,
respiratory therapist A respiratory therapist is a specialized healthcare practitioner trained in critical care and cardio-pulmonary medicine in order to work therapeutically with people who have acute critical conditions, cardiac and pulmonary disease. Respirator ...
,
paramedic A paramedic is a registered healthcare professional who works autonomously across a range of health and care settings and may specialise in clinical practice, as well as in education, leadership, and research. Not all ambulance personnel are p ...
, or other suitable person compressing a
bag valve mask A bag valve mask (BVM), sometimes known by the proprietary name Ambu bag or generically as a manual resuscitator or "self-inflating bag", is a hand-held device commonly used to provide positive pressure ventilation to patients who are not breathi ...
or set of bellows. Mechanical ventilation is termed "invasive" if it involves any instrument penetrating through the mouth (such as an endo
tracheal tube A tracheal tube is a catheter that is inserted into the trachea for the primary purpose of establishing and maintaining a patent airway and to ensure the adequate exchange of oxygen and carbon dioxide. Many different types of tracheal tubes are ...
) or the skin (such as a
tracheostomy Tracheotomy (, ), or tracheostomy, is a surgical airway management procedure which consists of making an incision (cut) on the anterior aspect (front) of the neck and opening a direct airway through an incision in the trachea (windpipe). The r ...
tube). There are two main
modes of mechanical ventilation Modes of mechanical ventilation are one of the most important aspects of the usage of mechanical ventilation. The mode refers to the method of inspiratory support. In general, mode selection is based on clinician familiarity and institutional pref ...
within the two divisions: positive pressure ventilation, where air (or another gas mix) is pushed into the
trachea The trachea, also known as the windpipe, is a Cartilage, cartilaginous tube that connects the larynx to the bronchi of the lungs, allowing the passage of air, and so is present in almost all air-breathing animals with lungs. The trachea extends ...
, and negative pressure ventilation, where air is, in essence, sucked into the lungs.
Tracheal intubation Tracheal intubation, usually simply referred to as intubation, is the placement of a flexible plastic catheter, tube into the vertebrate trachea, trachea (windpipe) to maintain an open airway or to serve as a conduit through which to administer ce ...
is often used for short-term
mechanical ventilation Mechanical ventilation, assisted ventilation or intermittent mandatory ventilation (IMV), is the medical term for using a machine called a ventilator to fully or partially provide artificial ventilation. Mechanical ventilation helps move air ...
. A tube is inserted through the nose (nasotracheal intubation) or mouth (orotracheal intubation) and advanced into the
trachea The trachea, also known as the windpipe, is a Cartilage, cartilaginous tube that connects the larynx to the bronchi of the lungs, allowing the passage of air, and so is present in almost all air-breathing animals with lungs. The trachea extends ...
. In most cases tubes with inflatable cuffs are used for protection against leakage and aspiration. Intubation with a cuffed tube is thought to provide the best protection against aspiration. Tracheal tubes inevitably cause pain and coughing. Therefore, unless a patient is unconscious or anesthetized for other reasons, sedative drugs are usually given to provide tolerance of the tube. Other disadvantages of tracheal intubation include damage to the mucosal lining of the
nasopharynx The pharynx (plural: pharynges) is the part of the throat behind the mouth and nasal cavity, and above the oesophagus and trachea (the tubes going down to the stomach and the lungs). It is found in vertebrates and invertebrates, though its struct ...
or
oropharynx The pharynx (plural: pharynges) is the part of the throat behind the mouth and nasal cavity, and above the oesophagus and trachea (the tubes going down to the stomach and the lungs). It is found in vertebrates and invertebrates, though its struc ...
and subglottic stenosis. In an emergency a
cricothyrotomy A cricothyrotomy (also called cricothyroidotomy) is an incision made through the skin and cricothyroid membrane to establish a patent airway during certain life-threatening situations, such as airway obstruction by a foreign body, angioedema, or ...
can be used by health care professionals, where an airway is inserted through a surgical opening in the
cricothyroid membrane The cricothyroid ligament (also known as the cricothyroid membrane or cricovocal membrane) is a ligament in the neck. It connects the cricoid cartilage to the thyroid cartilage. It prevents these cartilages from moving too far apart. It is cut dur ...
. This is similar to a
tracheostomy Tracheotomy (, ), or tracheostomy, is a surgical airway management procedure which consists of making an incision (cut) on the anterior aspect (front) of the neck and opening a direct airway through an incision in the trachea (windpipe). The r ...
but a
cricothyrotomy A cricothyrotomy (also called cricothyroidotomy) is an incision made through the skin and cricothyroid membrane to establish a patent airway during certain life-threatening situations, such as airway obstruction by a foreign body, angioedema, or ...
is reserved for emergency access. This is usually only used when there is a complete blockage of the
pharynx The pharynx (plural: pharynges) is the part of the throat behind the mouth and nasal cavity, and above the oesophagus and trachea (the tubes going down to the stomach and the lungs). It is found in vertebrates and invertebrates, though its struc ...
or there is massive maxillofacial injury, preventing other adjuncts being used.


Neurostimulation

Diaphragm pacing is the rhythmic application of electrical impulses to the diaphragm. Historically, this has been accomplished through the electrical stimulation of a phrenic nerve by an implanted receiver/electrode, though today an alternative option of attaching
percutaneous {{More citations needed, date=January 2021 In surgery, a percutaneous procedurei.e. Granger et al., 2012 is any medical procedure or method where access to inner organs or other tissue is done via needle-puncture of the skin, rather than by using ...
wires to the diaphragm exists.


History

The Greek physician
Galen Aelius Galenus or Claudius Galenus ( el, Κλαύδιος Γαληνός; September 129 – c. AD 216), often Anglicized as Galen () or Galen of Pergamon, was a Greek physician, surgeon and philosopher in the Roman Empire. Considered to be one of ...
may have been the first to describe artificial ventilation: "If you take a dead animal and blow air through its larynx through a reed, you will fill its bronchi and watch its lungs attain the greatest distention."
Vesalius Andreas Vesalius (Latinized from Andries van Wezel) () was a 16th-century anatomist, physician, and author of one of the most influential books on human anatomy, ''De Humani Corporis Fabrica Libri Septem'' (''On the fabric of the human body'' '' ...
too describes ventilation by inserting a reed or cane into the
trachea The trachea, also known as the windpipe, is a Cartilage, cartilaginous tube that connects the larynx to the bronchi of the lungs, allowing the passage of air, and so is present in almost all air-breathing animals with lungs. The trachea extends ...
of animals. In 1773, English physician
William Hawes William Hawes (178518 February 1846) was an English musician and composer. He was the Master of the Children of the Chapel Royal and musical director of the Lyceum Theatre bringing several notable works to the public's attention. Life Hawes was ...
(1736–1808) began publicizing the power of artificial ventilation to resuscitate people who superficially appeared to have drowned. For a year he paid a reward out of his own pocket to any one bringing him a body rescued from the water within a reasonable time of immersion.
Thomas Cogan Thomas Cogan (8 February 1736 – 2 February 1818) was an English nonconformist physician, a founder of the Royal Humane Society and philosophical writer. Life He was born at Rothwell, Northamptonshire on 8 February 1736, the half-brother of ...
, another English physician, who had become interested in the same subject during a stay at
Amsterdam Amsterdam ( , , , lit. ''The Dam on the River Amstel'') is the Capital of the Netherlands, capital and Municipalities of the Netherlands, most populous city of the Netherlands, with The Hague being the seat of government. It has a population ...
, where was instituted in 1767 a society for preservation of life from accidents in water, joined Hawes in his crusade. In the summer of 1774 Hawes and Cogan each brought fifteen friends to a meeting at the Chapter Coffee-house, St Paul's Churchyard, where they founded the
Royal Humane Society The Royal Humane Society is a British charity which promotes lifesaving intervention. It was founded in England in 1774 as the ''Society for the Recovery of Persons Apparently Drowned'', for the purpose of rendering first aid in cases of near dro ...
as a campaigning group for first aid and resuscitation. Some methods and equipment were similar to methods used today, such as wooden pipes used in the victims nostrils to blow air into the lungs. Others, bellows with a flexible tube for blowing tobacco smoke through the anus to revive vestigial life in the victim's intestines, were discontinued with the eventual further understanding of respiration. The 1856 works of English physician and physiologist Marshall Hall recommended against using any type of bellows/positive pressure ventilation, views that held sway for several decades. A common method of external manual manipulation, introduced in 1858, was the "Silvester Method" invented by Dr. Henry Robert Silvester in which a patient is laid on their back and their arms are raised above their head to aid inhalation and then pressed against their chest to aid exhalation. Another manual technique, the "prone pressure" method, was introduced by Sir Edward Sharpey Schafer in 1903. It involved placing the patient on his stomach and applying pressure to the lower part of the ribs. It was the standard method of artificial respiration taught in Red Cross and similar first aid manuals for decades, until mouth-to-mouth resuscitation became the preferred technique in mid-century. The shortcomings of manual manipulation led doctors in the 1880s to come up with improved methods of mechanical ventilation, including Dr. George Edward Fell's "Fell method" or "Fell Motor", consisting of a bellows and a breathing valve to pass air through a
tracheotomy Tracheotomy (, ), or tracheostomy, is a surgical airway management procedure which consists of making an incision (cut) on the anterior aspect (front) of the neck and opening a direct airway through an incision in the trachea (windpipe). The r ...
, and his collaboration with Dr.
Joseph O'Dwyer Joseph O'Dwyer (October 12, 1841 – January 7, 1898) was an American physician. He developed a valuable system of intubation in diphtheria cases. O'Dwyer is often cited as the "father of laryngeal intubation in croup". Life Joseph P. O'Dwyer was ...
to invent the Fell-O'Dwyer apparatus, a bellows and instruments for the insertion and extraction of a tube down the patients
trachea The trachea, also known as the windpipe, is a Cartilage, cartilaginous tube that connects the larynx to the bronchi of the lungs, allowing the passage of air, and so is present in almost all air-breathing animals with lungs. The trachea extends ...
.19th century pioneers of intensive therapy in North America. Part 1: George Edward Fell, Crit Care Resusc. 2007 Dec;9(4):377-9
abstract
/ref> Such methods were still looked upon as harmful and were not adopted for many years. In 2020, the supply of mechanical ventilation became a central question for public health officials due to 2019–20 coronavirus pandemic related shortages.


See also

* 2019–20 coronavirus pandemic related shortages#Mechanical ventilation *
Cardiopulmonary resuscitation Cardiopulmonary resuscitation (CPR) is an emergency procedure consisting of chest compressions often combined with artificial ventilation in an effort to manually preserve intact brain function until further measures are taken to restore spont ...
*
Medical emergency A medical emergency is an acute injury or illness that poses an immediate risk to a person's life or long-term health, sometimes referred to as a situation risking "life or limb". These emergencies may require assistance from another, qualified ...
*
Medical ventilator A ventilator is a piece of health technology, medical technology that provides mechanical ventilation by moving breathable air into and out of the lungs, to deliver breaths to a patient who is physically unable to breathe, or breathing insuffici ...
*
Two-balloon experiment The two-balloon experiment is an experiment involving interconnected balloons. It is used in physics classes as a demonstration of elasticity. Two identical balloons are inflated to different diameters and connected by means of a tube. The flow ...
* Charles Hederer, inventor of the pulmoventilateur *
Edward Albert Sharpey-Schafer Sir Edward Albert Sharpey-Schafer FRS FRSE FRCP LLD (2 June 1850 – 29 March 1935) was an English physiologist. He is regarded as a founder of endocrinology: in 1894 he discovered and demonstrated the existence of adrenaline together with G ...


References


External links


e-Medicine
article on mechanical ventilation along with technical information.

Resource of information for users of home mechanical ventilation.
''Mechanical Ventilation,''
(detailed slideshow presentation), by Amirali Nader, MD FCCP, Critical Care Medicine, Suburban Hospital, Johns Hopkins Medicine. {{Authority control Mechanical ventilation Emergency medicine Intensive care medicine Emergency medical services Respiratory system procedures Respiratory therapy First aid