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''Arrowsmith'' is a novel by American author
Sinclair Lewis Harry Sinclair Lewis (February 7, 1885 – January 10, 1951) was an American writer and playwright. In 1930, he became the first writer from the United States (and the first from the Americas) to receive the Nobel Prize in Literature, which was ...
, first published in 1925. It won the 1926
Pulitzer Prize The Pulitzer Prize () is an award for achievements in newspaper, magazine, online journalism, literature, and musical composition within the United States. It was established in 1917 by provisions in the will of Joseph Pulitzer, who had made h ...
(which Lewis declined). Lewis was greatly assisted in its preparation by science writer
Paul de Kruif Paul Henry de Kruif (, rhyming with "life") (1890–1971) was an American microbiologist and author of Dutch descent. Publishing as Paul de Kruif, he is most noted for his 1926 book, ''Microbe Hunters''. This book was not only a bestseller for a le ...
, who received 25% of the royalties on sales, although Lewis was listed as the sole author. ''Arrowsmith'' is an early major novel dealing with the culture of science. It was written in the period after the reforms of medical education flowing from the
Flexner Report The ''Flexner Report'' is a book-length landmark report of medical education in the United States and Canada, written by Abraham Flexner and published in 1910 under the aegis of the Carnegie Foundation. Many aspects of the present-day American m ...
on ''Medical Education in the United States and Canada: A Report to the
Carnegie Foundation for the Advancement of Teaching The Carnegie Foundation for the Advancement of Teaching (CFAT) is a U.S.-based education policy and research center. It was founded by Andrew Carnegie in 1905 and chartered in 1906 by an act of the United States Congress. Among its most nota ...
'', 1910, which had called on
medical schools in the United States This list of medical schools in the United States includes current and developing academic institutions which award the Doctor of Medicine (MD), or the Doctor of Osteopathic Medicine (DO) a professional level of education, either of which is requir ...
to adhere to mainstream science in their teaching and research. The book was adapted by Hollywood as '' Arrowsmith'' in 1931, starring
Ronald Colman Ronald Charles Colman (9 February 1891 – 19 May 1958) was an English-born actor, starting his career in theatre and silent film in his native country, then immigrating to the United States and having a successful Hollywood film career. He wa ...
and
Helen Hayes Helen Hayes MacArthur ( Brown; October 10, 1900 – March 17, 1993) was an American actress whose career spanned 80 years. She eventually received the nickname "First Lady of American Theatre" and was the second person and first woman to have w ...
. It was nominated for four
Academy Awards The Academy Awards, better known as the Oscars, are awards for artistic and technical merit for the American and international film industry. The awards are regarded by many as the most prestigious, significant awards in the entertainment ind ...
, including Best Adapted Screenplay.


Plot

''Arrowsmith'' tells the story of bright and scientifically minded Martin Arrowsmith of Elk Mills, Winnemac (the same fictional state in which several of Lewis's other novels are set), as he makes his way from a small town in the
Midwest The Midwestern United States, also referred to as the Midwest or the American Midwest, is one of four Census Bureau Region, census regions of the United States Census Bureau (also known as "Region 2"). It occupies the northern central part of ...
to the upper echelons of the scientific community at a prestigious foundation in New York City. Along the way he begins medical school. He becomes engaged to one woman, cheats on her with another woman, becomes engaged to the second woman and then finally invites both women to a lunch to settle the issue. He eventually insults his mentor, Max Gottlieb, and is suspended from school. He takes up life as an ordinary worker, then marries Leora with her family supporting him based on the promise that he will take up
private practice Private practice may refer to: *Private sector practice **Practice of law In its most general sense, the practice of law involves giving legal advice to clients, drafting legal documents for clients, and representing clients in legal negotiati ...
as the only doctor in tiny Wheatsylvania,
North Dakota North Dakota () is a U.S. state in the Upper Midwest, named after the Native Americans in the United States, indigenous Dakota people, Dakota Sioux. North Dakota is bordered by the Canadian provinces of Saskatchewan and Manitoba to the north a ...
. Frustrated with the work, he moves on to a job at the state Department of Public Health branch in Nautilus,
Iowa Iowa () is a state in the Midwestern region of the United States, bordered by the Mississippi River to the east and the Missouri River and Big Sioux River to the west. It is bordered by six states: Wisconsin to the northeast, Illinois to the ...
, then becomes romantically involved with the young daughter of its local director. After a series of political disputes, he resigns and joins the staff of an exclusive private hospital in Chicago. Finally, Arrowsmith is recognized by his former mentor, Gottlieb, for a
scientific paper : ''For a broader class of literature, see Academic publishing.'' Scientific literature comprises scholarly publications that report original empirical and theoretical work in the natural and social sciences. Within an academic field, scienti ...
he has written, and is invited to take a post with a wealthy and elite research institute in New York City. The book's climax deals with Arrowsmith's discovery of a
phage A bacteriophage (), also known informally as a ''phage'' (), is a duplodnaviria virus that infects and replicates within bacteria and archaea. The term was derived from "bacteria" and the Greek φαγεῖν ('), meaning "to devour". Bacter ...
that destroys bacteria and his experiences as he faces an outbreak of
bubonic plague Bubonic plague is one of three types of plague caused by the plague bacterium (''Yersinia pestis''). One to seven days after exposure to the bacteria, flu-like symptoms develop. These symptoms include fever, headaches, and vomiting, as well a ...
on a fictional Caribbean island. His scientific principles demand that he avoid its mass use on the Island until thoroughly tested, even at the expense of lives that might be saved. Only after his wife, Leora, and all the other people who came with him from the institute to the island die of plague, does he reluctantly abandon rigorous science and begins to treat everyone on the island with the phage. While there he becomes romantically involved with a wealthy socialite, whom he later marries. In spite of his life- saving, he regards his actions on the island as a complete betrayal of science and his principles. Upon his return to New York he is heralded as a public hero for his actions on the island. He is first promoted within the laboratory and then offered the directorship of the entire institute. He turns down the promotion, then abandons his new wife and infant son to work in the backwoods of
Vermont Vermont () is a state in the northeast New England region of the United States. Vermont is bordered by the states of Massachusetts to the south, New Hampshire to the east, and New York to the west, and the Canadian province of Quebec to ...
as an entirely independent scientist. When his wife finally offers to move to Vermont to be close to him, he tells her that he wants nothing to do with her and she should just go away.


Themes

The book contains considerable social commentary on the state and prospects of medicine in the United States in the 1920s. Arrowsmith is a progressive, even something of a rebel, and often challenges the existing state of affairs when he finds it wanting. This novel has been inspirational for several generations of pre-medical and medical students. There is much agonizing along the way concerning career and life decisions. While detailing Arrowsmith's pursuit of the noble ideals of medical research for the benefit of mankind and of selfless devotion to the care of patients, Lewis throws many less noble temptations and self-deceptions in Arrowsmith's path. The attractions of financial security, recognition, even wealth and power, lure Arrowsmith away from following the footsteps of his first mentor, the brilliant but abrasive bacteriologist Max Gottlieb. In the course of the novel Lewis describes many aspects of medical training, medical practice, scientific research, scientific fraud, medical ethics, public health, and personal/professional conflicts that are still relevant today. Professional jealousy, institutional pressures, greed, stupidity, and negligence are all satirically depicted, and Arrowsmith himself is exasperatingly self-involved. But there is also tireless dedication, and respect for the scientific method and intellectual honesty. Martin Arrowsmith shares some biographical elements with
Félix d'Herelle Felix may refer to: * Felix (name), people and fictional characters with the name Places * Arabia Felix is the ancient Latin name of Yemen * Felix, Spain, a municipality of the province Almería, in the autonomous community of Andalusia, ...
, who is identified in the novel as a co-discoverer of the bacteriophage and represented as having beaten Arrowsmith into publication with his results. Because of its detailed and gripping portrayal of experimental laboratory research as a practice, a profession, an ideology, a worldview, and a “prominent strand in modern culture, a way of life”, ''Arrowsmith'' is generally acknowledged as a classic 'science novel', focusing on moral dilemmas bio-medical researchers may encounter. Educator and school founder Lisa VanDamme describes using the ethical challenges and world outlook presented in Arrowsmith: “…I might give one class about the idealistic characters and in what way they are doomed to suffering in the world, another about those who abandon their ideals and achieve practical ‘success,’ another about the basic moral-practical dichotomy this implies, and another contrasting this view with that of… ther novelists” ''Arrowsmith'' has been compared with ''
The Citadel The Citadel, The Military College of South Carolina, commonly known simply as The Citadel, is a Public college, public United States senior military college, senior military college in Charleston, South Carolina. Established in 1842, it is one ...
'', published in 1937 by
A. J. Cronin Archibald Joseph Cronin (19 July 1896 – 6 January 1981), known as A. J. Cronin, was a Scottish physician and novelist. His best-known novel is ''The Citadel'' (1937), about a Scottish doctor who serves in a Welsh mining village before achievi ...
, which also deals with the experiences of a young idealistic doctor who tries to challenge and improve the existing system of medical practice. Sinclair’s scientific collaborator
Paul de Kruif Paul Henry de Kruif (, rhyming with "life") (1890–1971) was an American microbiologist and author of Dutch descent. Publishing as Paul de Kruif, he is most noted for his 1926 book, ''Microbe Hunters''. This book was not only a bestseller for a le ...
drew inspiration for locations and characters in ''Arrowsmith'' from specific sources. The laboratory work and experimental process of Max Gottlieb was based on the careers of
Frederick George Novy __NOTOC__ Frederick George Novy (December 9, 1864 – August 8, 1957) was an American bacteriologist, organic chemist, and instructor. Born in Chicago, Illinois, the third son of Joseph Novy and his wife Frances, grew up on the West Side, near t ...
and
Jacques Loeb Jacques Loeb (; ; April 7, 1859 – February 11, 1924) was a German-born American physiologist and biologist. Biography Jacques Loeb, firstborn son of a Jewish family from the German Eifel region, was educated at the universities of Berlin, Munic ...
. Loeb and De Kruif both worked at the
Rockefeller Institute for Medical Research The Rockefeller University is a private biomedical research and graduate-only university in New York City, New York. It focuses primarily on the biological and medical sciences and provides doctoral and postdoctoral education. It is classi ...
in New York, and Novy was De Kruif's longtime mentor. A writer in Public Health Reports commented in 2001 that the novel predicted many of the successes and problems affecting today's medical profession, such as the competing needs and goals of clinicians and medical scientists; commercial interests of pharmaceutical companies developing new medications and vaccines versus the need to seek for scientific truth; political and social difficulties in developing programs for protecting a community's public health; and the doctor's evolving role in American society. Scholars have found eerie parallels to the
COVID-19 Coronavirus disease 2019 (COVID-19) is a contagious disease caused by a virus, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first known case was COVID-19 pandemic in Hubei, identified in Wuhan, China, in December ...
crisis in the 1925 novel, and the many ethical dilemmas and challenges it presents.


Pulitzer Prize

Arrowsmith was awarded the 1926 Pulitzer Prize for Fiction, but Lewis declined the award. In a letter to the committee, he wrote: ''The New York Times'' reported that, according to observers, the real reason was that Lewis was still upset that '' Main Street'' did not win the prize in 1921.


Film, radio and television adaptations

The book's only theatrically released adaptation was the film '' Arrowsmith'' in 1931, featuring
Ronald Colman Ronald Charles Colman (9 February 1891 – 19 May 1958) was an English-born actor, starting his career in theatre and silent film in his native country, then immigrating to the United States and having a successful Hollywood film career. He wa ...
and
Helen Hayes Helen Hayes MacArthur ( Brown; October 10, 1900 – March 17, 1993) was an American actress whose career spanned 80 years. She eventually received the nickname "First Lady of American Theatre" and was the second person and first woman to have w ...
as Arrowsmith and Leora, and
Myrna Loy Myrna Loy (born Myrna Adele Williams; August 2, 1905 – December 14, 1993) was an American film, television and stage actress. Trained as a dancer, Loy devoted herself fully to an acting career following a few minor roles in silent films. ...
as socialite Mrs. Joyce Lanyon. It was nominated for four
Academy Awards The Academy Awards, better known as the Oscars, are awards for artistic and technical merit for the American and international film industry. The awards are regarded by many as the most prestigious, significant awards in the entertainment ind ...
, including Best Adapted Screenplay. ''
Lux Radio Theater ''Lux Radio Theatre'', sometimes spelled ''Lux Radio Theater'', a classic radio anthology series, was broadcast on the NBC Blue Network (1934–35) (owned by the National Broadcasting Company, later predecessor of American Broadcasting Company ...
'' presented a one-hour radio adaptation on October 25, 1937, starring Spencer Tracy and Fay Wray. Helen Hayes reprised her role as Leora in an hour-long adaptation on '' The Campbell Playhouse'' radio program along with
Orson Welles George Orson Welles (May 6, 1915 – October 10, 1985) was an American actor, director, producer, and screenwriter, known for his innovative work in film, radio and theatre. He is considered to be among the greatest and most influential f ...
as Arrowsmith. The program aired on February 3, 1939. ''
Cavalcade of America ''Cavalcade of America'' is an anthology drama series that was sponsored by the DuPont Company, although it occasionally presented musicals, such as an adaptation of ''Show Boat'', and condensed biographies of popular composers. It was initially ...
'' presented a version on February 23, 1942, with
Tyrone Power Tyrone Edmund Power III (May 5, 1914 – November 15, 1958) was an American actor. From the 1930s to the 1950s, Power appeared in dozens of films, often in swashbuckler roles or romantic leads. His better-known films include '' Jesse James'', ...
in the title role. In the 1950s and '60s, the book was adapted several times for television, and condensed versions of the story were produced for such television shows as ''Kraft Television Theater'' and ''DuPont Show of the Month''. A
Czech Czech may refer to: * Anything from or related to the Czech Republic, a country in Europe ** Czech language ** Czechs, the people of the area ** Czech culture ** Czech cuisine * One of three mythical brothers, Lech, Czech, and Rus' Places * Czech, ...
mini-series was produced in 1999, with Jan Stastny in the title role and Tereza Brodská as "Leora Tozerova". It is a popular myth that the rock band
Aerosmith Aerosmith is an American Rock music, rock band formed in Boston in 1970. The group consists of Steven Tyler (lead vocals), Joe Perry (musician), Joe Perry (guitar), Tom Hamilton (musician), Tom Hamilton (bass), Joey Kramer (drums) and Brad Whi ...
took its name from this book. Although the members were required to read this book in school, they have repeatedly and adamantly denied any connection. In fact, the name was initially rejected because they thought drummer Joey Kramer got the name from the Lewis novel. When he explained the different spelling and that the name came to him while listening to
Harry Nilsson Harry Edward Nilsson III (June 15, 1941 – January 15, 1994), sometimes credited as Nilsson, was an American singer-songwriter who reached the peak of his commercial success in the early 1970s. His work is characterized by pioneering vocal ove ...
's album ''
Aerial Ballet ''Aerial Ballet'' is the third studio album by American musician Harry Nilsson, released in July 1968. Overview ''Aerial Ballet'' was Nilsson's second album for RCA Victor, and was titled after the highwire circus act of his grandparents. It ...
'', the name was accepted by the other members.


References

; Bibliography * * *


External links

*
Arrowsmith - Project Gutenberg Australia
* * {{DEFAULTSORT:Arrowsmith 1925 American novels American novels adapted into films Harcourt (publisher) books Novels by Sinclair Lewis Novels set in North Dakota Novels set in New York (state) Novels set in the Caribbean Novels set in Vermont Pulitzer Prize for the Novel-winning works