Ariadne (also known as 4C-D, 4C-DOM, α-Et-2C-D, BL-3912, or dimoxamine) is a lesser-known psychedelic drug. It is a homologue of

2C-D 2C-D (2,5-dimethoxy-4-methylphenethylamine or 2C-M) is a psychedelic drug of the 2C family that is sometimes used as an entheogen. It was first synthesized in 1970 by a team from the Texas Research Institute of Mental Sciences, and its activity w ...

and DOM. Ariadne was first synthesized by Alexander Shulgin. In his book '' PiHKAL'', Shulgin reported testing Ariadne up to a dose of 32 mg, and reported that it produces

psychedelia Psychedelia refers to the psychedelic subculture of the 1960s and the psychedelic experience. This includes psychedelic art, psychedelic music and style of dress during that era. This was primarily generated by people who used psychedelic ...

at a bare threshold. Very little data exists about the pharmacological properties, metabolism, and toxicity of Ariadne in humans apart from Shulgin's limited testing. Shulgin reported that the drug was tested by Bristol Laboratories as an antidepressant, in an anecdote where he was explaining how human testing is invaluable (compared to animal testing) on drugs that change the state of the mind. He said, "Before they launched into a full multi-clinic study to determine if it's going to be worth the animal studies or not, every person on the board of directors took it." In an animal study, Ariadne was shown to produce stimulus generalization in rats trained to respond to the drug

MDMA 3,4-Methylenedioxymethamphetamine (MDMA), commonly seen in tablet form (ecstasy) and crystal form (molly or mandy), is a potent empathogen–entactogen with stimulant properties primarily used for recreational purposes. The desire ...

References

Substituted amphetamines Entactogens and empathogens 2,5-Dimethoxyphenethylamines Serotonin-norepinephrine-dopamine releasing agents {{psychoactive-stub

See also

References