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Vivisection () is
surgery
Surgery ''cheirourgikē'' (composed of χείρ, "hand", and ἔργον, "work"), via la, chirurgiae, meaning "hand work". is a medical specialty that uses operative manual and instrumental techniques on a person to investigate or treat a pat ...
conducted for experimental purposes on a living organism, typically animals with a
central nervous system
The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain and spinal cord. The CNS is so named because the brain integrates the received information and coordinates and influences the activity of all par ...
, to view living internal structure. The word is, more broadly, used as a
pejorative
A pejorative or slur is a word or grammatical form expressing a negative or a disrespectful connotation, a low opinion, or a lack of respect toward someone or something. It is also used to express criticism, hostility, or disregard. Sometimes, a ...
catch-all term for
experimentation on live animals[Tansey, E.M]
Review of ''Vivisection in Historical Perspective by Nicholaas A. Rupke
, book reviews, National Center for Biotechnology Information, p. 226. by organizations opposed to animal experimentation,
[Yarri, Donna]
''The Ethics of Animal Experimentation: A Critical Analysis and Constructive Christian Proposal
, Oxford University Press, 2005, p. 163. but the term is rarely used by practising scientists.
[ Human vivisection, such as live organ harvesting, has been perpetrated as a form of ]torture
Torture is the deliberate infliction of severe pain or suffering on a person for reasons such as punishment, extracting a confession, interrogation for information, or intimidating third parties. Some definitions are restricted to acts c ...
.
Animal vivisection
Research requiring vivisection techniques that cannot be met through other means is often subject to an external ethics
Ethics or moral philosophy is a branch of philosophy that "involves systematizing, defending, and recommending concepts of right and wrong behavior".''Internet Encyclopedia of Philosophy'' The field of ethics, along with aesthetics, concerns m ...
review in conception and implementation, and in many jurisdictions use of anesthesia
Anesthesia is a state of controlled, temporary loss of sensation or awareness that is induced for medical or veterinary purposes. It may include some or all of analgesia (relief from or prevention of pain), paralysis (muscle relaxation), ...
is legally mandated for any surgery likely to cause pain
Pain is a distressing feeling often caused by intense or damaging stimuli. The International Association for the Study of Pain defines pain as "an unpleasant sensory and emotional experience associated with, or resembling that associated with, ...
to any vertebrate
Vertebrates () comprise all animal taxa within the subphylum Vertebrata () ( chordates with backbones), including all mammals, birds, reptiles, amphibians, and fish. Vertebrates represent the overwhelming majority of the phylum Chordata, ...
.
In the United States, the Animal Welfare Act explicitly requires that any procedure that may cause pain use "tranquilizers, analgesics, and anesthetics" with exceptions when "scientifically necessary". The act does not define "scientific necessity" or regulate specific scientific procedures, but approval or rejection of individual techniques in each federally funded lab is determined on a case-by-case basis by the Institutional Animal Care and Use Committee
Institutional Animal Care and Use Committees (IACUCs) are centrally important in applying laws about animal research in the United States. Similar systems operate in other countries, but generally under different titles; for example, in Canada a t ...
, which contains at least one veterinarian, one scientist, one non-scientist, and one other individual from outside the university.
In the United Kingdom, any experiment involving vivisection must be licensed by the Home Secretary
The secretary of state for the Home Department, otherwise known as the home secretary, is a senior minister of the Crown in the Government of the United Kingdom. The home secretary leads the Home Office, and is responsible for all national ...
. The Animals (Scientific Procedures) Act 1986 "expressly directs that, in determining whether to grant a licence for an experimental project, 'the Secretary of State shall weigh the likely adverse effects on the animals concerned against the benefit likely to accrue.
In Australia
Australia, officially the Commonwealth of Australia, is a Sovereign state, sovereign country comprising the mainland of the Australia (continent), Australian continent, the island of Tasmania, and numerous List of islands of Australia, sma ...
, the Code of Practice "requires that all experiments must be approved by an Animal Experimentation Ethics Committee" that includes a "person with an interest in animal welfare who is not employed by the institution conducting the experiment, and an additional independent person not involved in animal experimentation."
Anti-vivisectionists have played roles in the emergence of the animal welfare
Animal welfare is the well-being of non-human animals. Formal standards of animal welfare vary between contexts, but are debated mostly by animal welfare groups, legislators, and academics. Animal welfare science uses measures such as longevity ...
and animal rights
Animal rights is the philosophy according to which many or all sentient animals have moral worth that is independent of their utility for humans, and that their most basic interests—such as avoiding suffering—should be afforded the sa ...
movements, arguing that animals and humans have the same natural rights
Some philosophers distinguish two types of rights, natural rights and legal rights.
* Natural rights are those that are not dependent on the laws or customs of any particular culture or government, and so are ''universal'', ''fundamental'' and ...
as living creatures, and that it is inherently immoral to inflict pain or injury on another living creature, regardless of the purpose or potential benefit to mankind.[
]
Vivisection and anti-vivisection in the 19th century
At the turn of the 19th century, medicine was undergoing a transformation. The emergence of hospitals and the development of more advanced medical tools such as the stethoscope are but a few of the changes in the medical field. There was also an increased recognition that medical practices needed to be improved, as many of the current therapeutics were based on unproven, traditional theories that may or may not have helped the patient recover. The demand for more effective treatment shifted emphasis to research with the goal of understanding disease mechanisms and anatomy. This shift had a few effects, one of which was the rise in patient experimentation, leading to some moral questions about what was acceptable in clinical trials and what was not. An easy solution to the moral problem was to use animals in vivisection experiments, so as not to endanger human patients. This, however, had its own set of moral obstacles, leading to the anti-vivisection movement.
François Magendie (1783–1855)
One polarizing figure in the anti-vivisection movement was François Magendie
__NOTOC__
François Magendie (6 October 1783 – 7 October 1855) was a French physiologist, considered a pioneer of experimental physiology. He is known for describing the foramen of Magendie. There is also a ''Magendie sign'', a downward a ...
. Magendie was a physiologist at the Académie Royale de Médecine in France, established in the first half of the 19th century. Magendie made several groundbreaking medical discoveries, but was far more aggressive than some of his other contemporaries with his use of animal experimentation. For example, the discovery of the different functionalities of dorsal and ventral spinal nerve roots was achieved by both Magendie, as well as a Scottish anatomist named Charles Bell. Bell used an unconscious rabbit because of "the protracted cruelty of the dissection", which caused him to miss that the dorsal roots were also responsible for sensory information. Magendie, on the other hand, used conscious, six-week-old puppies for his own experiments. While Magendie's approach was more of an infringement on what would today be referred to as animal rights, both Bell and Magendie used the same justification for vivisection: the cost of animal lives and experimentation was well worth it for the benefit of humanity.
Many viewed Magendie's work as cruel and unnecessarily torturous. One note is that Magendie carried out many of his experiments before the advent of anesthesia, but even after ether was discovered it was not used in any of his experiments or classes. Even during the period before anesthesia, other physiologists expressed their disgust with how he conducted his work. One such visiting American physiologist describes the animals as "victims" and the apparent sadism that Magendie displayed when teaching his classes. The cruelty in such experiments actually even led to Magendie's role as an important figure in animal-rights legislation, such as his experiments being cited in the drafting of the British Cruelty to Animals Act 1876 and Cruel Treatment of Cattle Act 1822
The Cruel Treatment of Cattle Act 1822 (3 Geo. IV c. 71) was an Act of the Parliament of the United Kingdom with the long title "An Act to prevent the cruel and improper Treatment of Cattle"; it is sometimes known as Martin's Act, after the MP an ...
, otherwise known as Martin's Act, with its namesake, Irish MP and well known anti-cruelty campaigner Richard Martin describing Magendle as "disgrace to Society" after one of Magendle's public vivisections, described by Martin as "anatomical theatres", which was widely commented on at the time reportedly involving a greyhounds dissection potentially over two days. Magendle faced widespread opposition in British society, among the general public but also his contemporaries, including Dr. William Sharpey who described his experiments aside from cruel as "purposeless" and “without sufficient object", a feeling he claimed was shared among other physiologists
David Ferrier and the Cruelty to Animals Act 1876
The Cruelty to Animals Act, 1876
The Cruelty to Animals Act 1876 ( 39 & 40 Vict. c. 77.) was an Act of the Parliament of the United Kingdom which set limits on the practice of, and instituted a licensing system for animal experimentation, amending the Cruelty to Animals Act 1 ...
in Britain determined that one could only conduct vivisection on animals with the appropriate license from the state, and that the work the physiologist was doing had to be original and absolutely necessary. The stage was set for such legislation by physiologist David Ferrier
Sir David Ferrier FRS (13 January 1843 – 19 March 1928) was a pioneering Scottish neurologist and psychologist. Ferrier conducted experiments on the brains of animals such as monkeys and in 1881 became the first scientist to be prosecuted u ...
. Ferrier was a pioneer in understanding the brain and used animals to show that certain locales of the brain corresponded to bodily movement elsewhere in the body in 1873. He put these animals to sleep, and caused them to move unconsciously with a probe. Ferrier was successful, but many decried his use of animals in his experiments. Some of these arguments came from a religious standpoint. Some were concerned that Ferrier's experiments would separate God from the mind of man in the name of science. Some of the anti-vivisection movement in England had its roots in Evangelicalism and Quakerism. These religions already had a distrust for science, only intensified by the recent publishing of Darwin's Theory of Evolution in 1859.
Neither side was pleased with how the Cruelty to Animals Act 1876 was passed. The scientific community felt as though the government was restricting their ability to compete with the quickly advancing France and Germany with new regulations. The anti-vivisection movement was also unhappy, but because they believed that it was a concession to scientists for allowing vivisection to continue at all. Ferrier would continue to vex the anti-vivisection movement in Britain with his experiments when he had a debate with his German opponent, Friedrich Goltz. They would effectively enter the vivisection arena, with Ferrier presenting a monkey, and Goltz presenting a dog, both of which had already been operated on. Ferrier won the debate, but did not have a license, leading the anti-vivisection movement to sue him in 1881. Ferrier was not found guilty, as his assistant was the one operating, and his assistant did have a license. Ferrier and his practices gained public support, leaving the anti-vivisection movement scrambling. They made the moral argument that given recent developments, scientists would venture into more extreme practices to operating on "the cripple, the mute, the idiot, the convict, the pauper, to enhance the 'interest' of he physiologist's
He or HE may refer to:
Language
* He (pronoun), an English pronoun
* He (kana), the romanization of the Japanese kana へ
* He (letter), the fifth letter of many Semitic alphabets
* He (Cyrillic), a letter of the Cyrillic script called ''He'' in ...
experiments".
Human vivisection
It is possible that human vivisection was practised by some Greek anatomists in Alexandria in the 3rd century BC. Celsus in ''De Medicina'' states that Herophilos of Alexandria vivisected some criminals sent by the King, with the early Christian writer Tertullian
Tertullian (; la, Quintus Septimius Florens Tertullianus; 155 AD – 220 AD) was a prolific early Christian author from Carthage in the Roman province of Africa. He was the first Christian author to produce an extensive corpus of L ...
states that Herophilos vivisected at least 600 live prisoners although the accuracy of this claim is disputed by many historians.[Tertullian, De Anima 10.]
Unit 731, a biological
Biology is the scientific study of life. It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. For instance, all organisms are made up of cells that process hereditary in ...
and chemical warfare
Chemical warfare (CW) involves using the toxic properties of chemical substances as weapons. This type of warfare is distinct from nuclear warfare, biological warfare and radiological warfare, which together make up CBRN, the military acronym ...
research and development unit of the Imperial Japanese Army
The was the official ground-based armed force of the Empire of Japan from 1868 to 1945. It was controlled by the Imperial Japanese Army General Staff Office and the Ministry of the Army, both of which were nominally subordinate to the Emperor o ...
, undertook lethal human experimentation during the period that comprised both the Second Sino-Japanese War
The Second Sino-Japanese War (1937–1945) or War of Resistance (Chinese term) was a military conflict that was primarily waged between the Republic of China and the Empire of Japan. The war made up the Chinese theater of the wider Pacific Th ...
and the Second World War
World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposin ...
(1937–1945). In Mindanao
Mindanao ( ) ( Jawi: مينداناو) is the second-largest island in the Philippines, after Luzon, and seventh-most populous island in the world. Located in the southern region of the archipelago, the island is part of an island group of ...
, Moro Muslim prisoners of war were subjected to various forms of vivisection by the Japanese, in many cases without anesthesia.["Unmasking Horror"]
Nicholas D. Kristof (March 17, 1995) New York Times. A special report.; Japan Confronting Gruesome War Atrocity
Nazi human experimentation involved many medical experiments on live subjects, such as vivisections by Josef Mengele, usually without anesthesia.
Vivisection without anesthesia was an execution method employed by the Khmer Rouge
The Khmer Rouge (; ; km, ខ្មែរក្រហម, ; ) is the name that was popularly given to members of the Communist Party of Kampuchea (CPK) and by extension to the regime through which the CPK ruled Cambodia between 1975 and 1979. ...
at the Tuol Sleng prison. Only seven people out of an estimated 20,000 prisoners survived the four-year run of the prison before its liberation by the Vietnamese army in January 1979.
See also
* Alternatives to animal testing
*American Anti-Vivisection Society
The American Anti-Vivisection Society (AAVS) is an organization created with the goal of eliminating a number of different procedures done by medical and cosmetic groups in relation to animal cruelty in the United States. It seeks to help the be ...
*Animal testing regulations
Animal testing regulations are guidelines that permit and control the use of non-human animals for scientific experimentation. They vary greatly around the world, but most governments aim to control the number of times individual animals may be us ...
*Bionics
Bionics or biologically inspired engineering is the application of biological methods and systems found in nature to the study and design of engineering systems and modern technology.
The word ''bionic'', coined by Jack E. Steele in August 1 ...
*Cruelty to animals
Cruelty to animals, also called animal abuse, animal neglect or animal cruelty, is the infliction by omission (neglect) or by commission by humans of suffering or harm upon non-human animals. More narrowly, it can be the causing of harm or suf ...
*Dissection
Dissection (from Latin ' "to cut to pieces"; also called anatomization) is the dismembering of the body of a deceased animal or plant to study its anatomical structure. Autopsy is used in pathology and forensic medicine to determine the cause o ...
*Experimentation on prisoners
Throughout history, prisoners have been frequent participants in scientific, medical and social human subject research. Some of the research involving prisoners has been exploitative and cruel. Many of the modern protections for human subjects ev ...
, including vivisection
*History of animal testing
The history of animal testing goes back to the writings of the Ancient Greeks in the 4th and 3rd centuries BCE, with Aristotle (384–322 BCE) and Erasistratus (304–258 BCE) one of the first documented to perform experiments on nonhuman animals. ...
* Human subject research
*Intrinsic value (animal ethics)
The intrinsic value of a human, or any other sentient animal, is value which originates within itself, the value it confers on itself by desiring its own lived experience as an end in itself. Intrinsic value exists wherever self-valuing beings ...
*Lingchi
''Lingchi'' (; ), translated variously as the slow process, the lingering death, or slow slicing, and also known as death by a thousand cuts, was a form of torture and execution used in China from roughly 900 CE up until the practice ended aro ...
, an execution method in Imperial China
* New England Anti-Vivisection Society
*Pro-Test
Pro-Test was a British group that promoted and supported animal testing in medical research. It was founded on 29 January 2006 to counter SPEAK, an animal-rights campaign opposing the construction by Oxford University of a biomedical and animal ...
*Speaking of Research
Speaking of Research (SR) is an international group which "aims to provide accurate information about the importance of animal research in medical and veterinary science". It was founded in March 2008 by Tom Holder, an "energetic young British ac ...
References
Further reading
{{Authority control
Vivisection
Animal testing techniques
Biology experiments
Human subject research
Laboratory techniques
Physiology
Research methods