Anti-Jo1 is an
anti-nuclear antibody.
Anti-Jo1 has been associated with
inflammatory myopathies
Inflammatory myopathy is disease featuring weakness and inflammation of muscles and (in some types) muscle pain. The cause of much inflammatory myopathy is unknown (idiopathic), and such cases are classified according to their symptoms and medical ...
such as
polymyositis,
dermatomyositis and
antisynthetase syndrome
Anti-synthetase syndrome is an autoimmune disease associated with interstitial lung disease, dermatomyositis, and polymyositis.
Signs and symptoms
As a syndrome, this condition is poorly defined. Diagnostic criteria require one or more antisynth ...
.
It has
histidine-tRNA ligase as a target.
References
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Autoantibodies