Derzsy's disease is caused by ''Anseriform dependoparvovirus 1'', in the ''

Parvoviridae Parvoviruses are a family of animal viruses that constitute the family ''Parvoviridae''. They have linear, single-stranded DNA (ssDNA) genomes that typically contain two genes encoding for a replication initiator protein, called NS1, and the pr ...

'' family. It affects

geese A goose (plural, : geese) is a bird of any of several waterfowl species in the family (biology), family Anatidae. This group comprises the genera ''Anser (bird), Anser'' (the grey geese and white geese) and ''Branta'' (the black geese). Some o ...

and

Muscovy duck The Muscovy duck (''Cairina moschata'') is a large duck native to the Americas, from the Rio Grande Valley of Texas and Mexico south to Argentina and Uruguay. Small wild and feral breeding populations have established themselves in the United Sta ...

s. The virus is shed in the faeces and thus

transmission Transmission may refer to: Medicine, science and technology * Power transmission ** Electric power transmission ** Propulsion transmission, technology allowing controlled application of power *** Automatic transmission *** Manual transmission *** ...

is horizontal, via the direct faecal-oral route and also indirectly via

fomite A fomite () or fomes () is any inanimate object that, when contaminated with or exposed to infectious agents (such as pathogenic bacteria, viruses or fungi), can transfer disease to a new host. Transfer of pathogens by fomites A fomite is any ina ...

Vertical transmission Vertical transmission of symbionts is the transfer of a microbial symbiont from the parent directly to the offspring. Many metazoan species carry symbiotic bacteria which play a mutualistic, commensal, or parasitic role. A symbiont is acquire ...

is also possible. Clinical disease only occurs in young geese and ducks between birth and 4–5 weeks of age.

Epidemiology

Several genotypes have been described.Liu HM, Wang H, Tian XJ, Zhang S, Zhou XH, Qi KZ, Pan L (2013) Complete genome sequence of goose parvovirus Y strain isolated from Muscovy ducks in China. Virus Genes The genotype is based upon the sequence of the VP3 protein.

Clinical signs and diagnosis

Acute disease leads to death in most birds between the ages of 7–10 days. Clinical signs are quite limited in those cases. Older animals tend to show severe systemic and neurological signs and diarrhoea. Adults do not show any clinical signs.Derzsy's Disease
expert reviewed and published by

WikiVet WikiVet is a wiki of veterinary content based on the MediaWiki platform. The website is a collaborative initiative between various veterinary schools, and its content covers the entire veterinary curriculum. WikiVet is part of the WikiVet Educatio ...

, accessed 10 October 2011. Viral isolation should be attempted for diagnosis, and

immunofluorescence Immunofluorescence is a technique used for light microscopy with a fluorescence microscope and is used primarily on microbiological samples. This technique uses the specificity of antibodies to their antigen to target fluorescent dyes to specif ...

and

electron microscopy An electron microscope is a microscope that uses a beam of accelerated electrons as a source of illumination. As the wavelength of an electron can be up to 100,000 times shorter than that of visible light photons, electron microscopes have a hi ...

can confirm the viral infection. Pathological changes may also help the diagnosis.

Treatment and control

No treatment exists for the viral infection.

Antibiotic An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of ...

s may help prevent secondary infections.

Vaccination Vaccination is the administration of a vaccine to help the immune system develop immunity from a disease. Vaccines contain a microorganism or virus in a weakened, live or killed state, or proteins or toxins from the organism. In stimulating ...

is available in different forms, usually for naive flocks. Good

biosecurity Biosecurity refers to measures aimed at preventing the introduction and/or spread of harmful organisms (e.g. viruses, bacteria, etc.) to animals and plants in order to minimize the risk of transmission of infectious disease. In agriculture, thes ...

measures should be maintained including adequate quarantine, isolation, separation of different age groups and

disinfection A disinfectant is a chemical substance or compound used to inactivate or destroy microorganisms on inert surfaces. Disinfection does not necessarily kill all microorganisms, especially resistant bacterial spores; it is less effective than st ...

References

{{Taxonbar, from=Q18973791 Viral diseases Poultry diseases