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Angucyclines are
Angucyclines are antibiotics
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention o ...
isolated from ''Streptomyces
''Streptomyces'' is the largest genus of Actinomycetota and the type genus of the family Streptomycetaceae. Over 500 species of ''Streptomyces'' bacteria have been described. As with the other Actinomycetota, streptomycetes are gram-positive, ...
'' species, which are used in chemotherapy as cytostatics against various types of cancer. The angucyclines include for example aquayamycin
Aquayamycin is an anthraquinone derivative.
It is an inhibitor of the enzyme tyrosine hydroxylase
Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to L-3,4- ...
, the landomycins, moromycins, saquayamycins
320px, Saquayamycin A
320px, Saquayamycin B
Saquayamycins are "aquayamycin
Aquayamycin is an anthraquinone derivative.
It is an inhibitor of the enzyme tyrosine hydroxylase
Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme res ...
, urdamycins, and vineomycins.
See also
*Anthracyclines
Anthracyclines are a class of drugs used in cancer chemotherapy that are extracted from ''Streptomyces'' bacterium. These compounds are used to treat many cancers, including leukemias, lymphomas, breast, stomach, uterine, ovarian, bladder cance ...
References
{{antibiotic-stub