Andrew Paul Feinberg (born August 5, 1952) is the director of the Center for
Epigenetics
In biology, epigenetics is the study of stable phenotypic changes (known as ''marks'') that do not involve alterations in the DNA sequence. The Greek prefix '' epi-'' ( "over, outside of, around") in ''epigenetics'' implies features that are "o ...
, chief of the Division of Molecular Medicine in the Department of Medicine, and the King Fahd Professor of Medicine, Oncology, Molecular Biology & Genetics in the
School of Medicine
A medical school is a tertiary educational institution, or part of such an institution, that teaches medicine, and awards a professional degree for physicians. Such medical degrees include the Bachelor of Medicine, Bachelor of Surgery (MBBS, MB ...
at
Johns Hopkins University
Johns Hopkins University (Johns Hopkins, Hopkins, or JHU) is a private university, private research university in Baltimore, Maryland. Founded in 1876, Johns Hopkins is the oldest research university in the United States and in the western hem ...
.
Andrew Feinberg received his B.A. in 1973 and M.D. in 1976 from the accelerated medical program at Johns Hopkins University, as well as an M.P.H. from Johns Hopkins in 1981. He did his residency in internal medicine, followed by a fellowship in genetics at Hopkins. He did a postdoctoral fellowship in developmental biology at
UCSD
The University of California, San Diego (UC San Diego or colloquially, UCSD) is a public university, public Land-grant university, land-grant research university in San Diego, California. Established in 1960 near the pre-existing Scripps Insti ...
where he researched the multiple differentiation paths of ''
Dictyostelium discoideum''. His research into hereditary inheritance of traits outside of DNA was initially seen as controversial, and he was told that if he continued this work, his funding would be cut off.
Dr. Feinberg discovered epigenetic alterations in human cancer with
Bert Vogelstein
Bert Vogelstein (born 1949) is director of the Ludwig Center, Clayton Professor of Oncology and Pathology and a Howard Hughes Medical Institute investigator at The Johns Hopkins Medical School and Sidney Kimmel Comprehensive Cancer Center. A pion ...
in 1983. He is also credited with the discovery of
gene imprinting in humans.
He has made many contributions to the field of epigenetics in cancer, and discovered the molecular basis of
Beckwith-Wiedemann syndrome.
[ He pursued this work while he was an ]HHMI
The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, fil ...
Investigator at the University of Michigan
, mottoeng = "Arts, Knowledge, Truth"
, former_names = Catholepistemiad, or University of Michigania (1817–1821)
, budget = $10.3 billion (2021)
, endowment = $17 billion (2021)As o ...
from 1986-1994, when he returned to Johns Hopkins as King Fahd Professor of Molecular Medicine in the Department of Medicine.
Awards
* Delta Omega, National Public Health Honorary Society, 1981
* American Society for Clinical Investigation, 1990
* Association of American Physicians, 1995
* ISI, Most Cited Authors List (Top 0.1%), 2001
* MERIT Award
The NIH MERIT award (Method To Extend Research in Time) Award (R37) was created by the National Institutes of Health
The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary age ...
, National Cancer Institute
The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. ...
, 2001
*Elected Member of the Institute of Medicine
The National Academy of Medicine (NAM), formerly called the Institute of Medicine (IoM) until 2015, is an American nonprofit, non-governmental organization. The National Academy of Medicine is a part of the National Academies of Sciences, E ...
of the National Academy of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
, 2007
*Elected Member of the National Academy of Medicine, 2007
* Wallenberg Fellow, Royal Swedish Academy of Sciences
The Royal Swedish Academy of Sciences ( sv, Kungliga Vetenskapsakademien) is one of the Swedish Royal Academies, royal academies of Sweden. Founded on 2 June 1739, it is an independent, non-governmental scientific organization that takes special ...
, 2009
*Elected Fellow of the American Academy of Arts and Sciences
The American Academy of Arts and Sciences (abbreviation: AAA&S) is one of the oldest learned societies in the United States. It was founded in 1780 during the American Revolution by John Adams, John Hancock, James Bowdoin, Andrew Oliver, and ...
, 2009American Association for the Advancement of Science
The American Association for the Advancement of Science (AAAS) is an American international non-profit organization with the stated goals of promoting cooperation among scientists, defending scientific freedom, encouraging scientific respons ...
, 2011
*Award for Excellence in Molecular Diagnostics, Association for Molecular Pathology
The Association for Molecular Pathology (abbreviated AMP) is a professional association of individuals serving patients through molecular diagnostics testing. Founded in 1995, the Association has more than 2,800 members in over 50 countries.
Mol ...
, 2017
Publications
Feinberg has more than 92,000 citations in Google Scholar and an h-index of 112.
He was among the top 1% most cited in the world for subject field and year of publication in the 2019 and 2020 Thomson Reuters
Thomson Reuters Corporation ( ) is a Canadian multinational media conglomerate. The company was founded in Toronto, Ontario, Canada, where it is headquartered at the Bay Adelaide Centre.
Thomson Reuters was created by the Thomson Corpora ...
Highly Cited Researchers reports.
Pubmed citations
Google Scholar citations
Highly Cited Articles (''more than 1500 citations'')
* 2004 with B Tycko, ''The history of cancer epigenetics'', in: ''Nature Reviews Cancer''. Vol. 4, nº 2; 143-153.
* 1983 with B Vogelstein, ''Hypomethylation distinguishes genes of some human cancers from their normal counterparts'', in: ''Nature''. Vol. 301, nº 5895; 89-92.
* 2010 with K Kim, A Doi, B Wen, K Ng, R Zhao, P Cahan, J Kim, MJ Aryee, H Ji, et al, ''Epigenetic memory in induced pluripotent stem cells'', in: ''Nature''. Vol. 467, nº 7313; 285-290.
* 2009 with RA Irizarry, C Ladd-Acosta, B Wen, Z Wu, C Montano, P Onyango, H Cui, et al, ''The human colon cancer methylome shows similar hypo-and hypermethylation at conserved tissue-specific CpG island shores'', in: ''Nature Genetics''. Vol. 41, nº 2; 178-186.
* 2006 with R Ohlsson, S Henikoff, ''The epigenetic progenitor origin of human cancer'', in: ''Nature Reviews Genetics''. Vol. 7, nº 1; 21-33.
* 2014 with MJ Aryee, AE Jaffe, H Corrada-Bravo, C Ladd-Acosta, ''Minfi: a flexible and comprehensive Bioconductor package for the analysis of Infinium DNA methylation microarrays'', in: ''Bioinformatics''. Vol. 30, nº 10; 1363-1369.
* 2007, ''Phenotypic plasticity and the epigenetics of human disease'', in: ''Nature''. Vol. 447, nº 7143; 433-440.
References
{{DEFAULTSORT:Feinberg, Andrew
1952 births
Living people
Fellows of the American Academy of Arts and Sciences
Johns Hopkins Bloomberg School of Public Health alumni
Johns Hopkins Biomedical Engineering faculty
Johns Hopkins School of Medicine alumni
Howard Hughes Medical Investigators
Epigeneticists
Fellows of the American Association for the Advancement of Science
Members of the National Academy of Medicine
University of Michigan faculty