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''Phellodendron amurense'' is a species of tree in the family Rutaceae, commonly called the Amur cork tree. It is a major source of ''
huáng bò Huáng bǎi (黃 栢 ''or'' 黃 栢, literally "yellow fir"), huáng bó (黃 柏) or huáng bò (黃 檗) is one of the fifty fundamental herbs of traditional Chinese medicine. Known also as Cortex Phellodendri, it is the bark of one of two spec ...
'' ( or
Huang or Hwang may refer to: Location * Huang County, former county in Shandong, China, current Longkou City * Yellow River, or Huang River, in China * Huangshan, mountain range in Anhui, China * Huang (state), state in ancient China. * Hwang Riv ...
), one of the
50 fundamental herbs Chinese herbology () is the theory of traditional Chinese herbal therapy, which accounts for the majority of treatments in traditional Chinese medicine (TCM). A ''Nature'' editorial described TCM as "fraught with pseudoscience", and said that t ...
used in
traditional Chinese medicine Traditional Chinese medicine (TCM) is an alternative medical practice drawn from traditional medicine in China. It has been described as "fraught with pseudoscience", with the majority of its treatments having no logical mechanism of action ...
. The
Ainu people The Ainu are the indigenous people of the lands surrounding the Sea of Okhotsk, including Hokkaido Island, Northeast Honshu Island, Sakhalin Island, the Kuril Islands, the Kamchatka Peninsula and Khabarovsk Krai, before the arrival of the Y ...
used this plant, called shikerebe-ni, as a painkiller. It is known as ''hwangbyeok'' in Korean and (キハダ) ''kihada'' in Japanese. It is native to eastern Asia: northern China, northeast China, Korea,
Ussuri The Ussuri or Wusuli (russian: Уссури; ) is a river that runs through Khabarovsk and Primorsky Krais, Russia and the southeast region of Northeast China. It rises in the Sikhote-Alin mountain range, flowing north and forming part of the Si ...
,
Amur The Amur (russian: река́ Аму́р, ), or Heilong Jiang (, "Black Dragon River", ), is the world's List of longest rivers, tenth longest river, forming the border between the Russian Far East and Northeast China, Northeastern China (Inne ...
, and Japan, the Amur cork tree is considered invasive in many parts of North America. The State of Massachusetts lists it as a noxious weed.Bruce Marlin
''Phellodendron amurense''
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Medicinal use

It has been used as a Chinese traditional medicine for the treatment of meningitis, bacillary dysentery, pneumonia, tuberculosis, tumours, jaundice and liver cirrhosis. Used orally to treat abdominal pain, diarrhoea, gastroenteritis and urinary tract infections. ''Phellodendron amurense'' may protect cartilage against
osteoarthritis Osteoarthritis (OA) is a type of degenerative joint disease that results from breakdown of joint cartilage and underlying bone which affects 1 in 7 adults in the United States. It is believed to be the fourth leading cause of disability in the w ...
progression. It may prove to be a potentially important chemopreventive agent for lung cancer. ''Phellodendron amurense'' is able to inhibit prostatic contractility suggesting that it may be useful in the treatment of urological disorders caused by prostatic urethral obstruction such as benign prostatic hyperplasia (BPH).
Nexrutine Huáng bǎi ( 黃 栢 ''or'' 黃 栢, literally "yellow fir"), huáng bó ( 黃 柏) or huáng bò ( 黃 檗) is one of the fifty fundamental herbs of traditional Chinese medicine. Known also as Cortex Phellodendri, it is the bark of one of two ...
(bark extract from ''Phellodendron amurense'') may have potential to prevent prostate tumor development. Proprietary extracts of ''
Magnolia officinalis ''Magnolia officinalis'' (commonly called houpu magnolia or magnolia-bark) is a species of ''Magnolia'' native to the mountains and valleys of China at altitudes of 300–1500 m. Identification It is a deciduous tree growing to 20 m in height ...
'' and ''Phellodendron amurense'' may help overweight/obese people. Compounds in the leaves ( quercetin, quercetin-3-''O''-beta-D-glucoside, quercetin-3-''O''-beta-D-galactoside and kaempferol-3-''O''-beta-D-glucoside) demonstrated significant free radical scavenging activity comparable to
vitamin E Vitamin E is a group of eight fat soluble compounds that include four tocopherols and four tocotrienols. Vitamin E deficiency, which is rare and usually due to an underlying problem with digesting dietary fat rather than from a diet low in vitami ...
. The tree has both antibiotic and antimicrobial properties due to the alkaloids contained within the plant material. The major chemical constituents of its bark are the isoquinoline alkaloids, palmatine, jatrorrhizine, phellodendorine with berberine found within the leaves. The indole alkaloid has also been found in the roots of the young dioecious trees. Dye extracted from the bark was used historically across East Asia to color paper for sutras and other documents, including the Diamond Sutra. The yellow dye protected against insect damage.


Oil

Amur cork tree fruit oil is a pressed oil extracted from the fruit of ''Phellodendron amurense''. The bark of the tree is an important herbal medicine in
China China, officially the People's Republic of China (PRC), is a country in East Asia. It is the world's most populous country, with a population exceeding 1.4 billion, slightly ahead of India. China spans the equivalent of five time zones and ...
. The oil has insecticidal properties similar to pyrethrum. The oil contains a variety of biologically active substances, including
flavonoid Flavonoids (or bioflavonoids; from the Latin word ''flavus'', meaning yellow, their color in nature) are a class of polyphenolic secondary metabolites found in plants, and thus commonly consumed in the diets of humans. Chemically, flavonoids ...
s ( diosmin),
alkaloid Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar ...
s (
berberine Berberine is a quaternary ammonium salt from the protoberberine group of benzylisoquinoline alkaloids found in such plants as ''Berberis vulgaris'' (barberry), ''Berberis aristata'' (tree turmeric), ''Mahonia aquifolium'' (Oregon grape), ''Hydra ...
,
jatrorrhizine Jatrorrhizine is a protoberberine alkaloid found in some plant species, such as '' Enantia chlorantha'' (Annonaceae). Synonyms that may be encountered include jateorrhizine, neprotin, jatrochizine, jatrorhizine, and yatrorizine. Bioactive effect ...
,
palmatine Palmatine is a protoberberine alkaloid found in several plants including ''Phellodendron amurense'', ''Coptis Chinensis'' (Rhizoma coptidis, chinese goldthread) and '' Corydalis yanhusuo'', ''Tinospora cordifolia'' (gurjo, heart-leaved moonseed), ...
),
saponin Saponins (Latin "sapon", soap + "-in", one of), also selectively referred to as triterpene glycosides, are bitter-tasting usually toxic plant-derived organic chemicals that have a foamy quality when agitated in water. They are widely distributed ...
s, and coumarins. Medicinal applications of the oil include treatment of
pancreatitis Pancreatitis is a condition characterized by inflammation of the pancreas. The pancreas is a large organ behind the stomach that produces digestive enzymes and a number of hormones. There are two main types: acute pancreatitis, and chronic pancr ...
, reduction of
cholesterol Cholesterol is any of a class of certain organic molecules called lipids. It is a sterol (or modified steroid), a type of lipid. Cholesterol is biosynthesized by all animal cells and is an essential structural component of animal cell mem ...
and
sugar Sugar is the generic name for sweet-tasting, soluble carbohydrates, many of which are used in food. Simple sugars, also called monosaccharides, include glucose, fructose, and galactose. Compound sugars, also called disaccharides or double ...
in
blood Blood is a body fluid in the circulatory system of humans and other vertebrates that delivers necessary substances such as nutrients and oxygen to the cells, and transports metabolic waste products away from those same cells. Blood in the c ...
and the treatment of various skin diseases.


Chemistry

Essential oils: * Fruit oil contains myrcene (62.3–70.3%) and
β-caryophyllene Caryophyllene (), more formally (−)-β-caryophyllene, (BCP), is a natural bicyclic sesquiterpene that is a constituent of many essential oils, especially clove oil, the oil from the stems and flowers of ''Syzygium aromaticum'' (cloves), the esse ...
(6.8–10.5%) * Leaf oil contains β-elemol (18.5%) and (''Z'')-β-ocimene (12.6%) * Flower oil contains (''Z'')-β-ocimene (9.5%), β-elemol (9.4%), myrcene (7.8%) and nonacosane (7.7%) Amurensin, a ''tert''-amyl alcohol derivative of kaempferol 7-''O''-glucoside, can be found in ''P. amurense''.


Gallery

Phellodendron amurense (12).JPG, Leaf Phellodendron amurense (15).JPG, Tree Phellodendron amurense (18).JPG, Bark Phellodendron amurense seeds, by Omar Hoftun.jpg, Seeds


See also

* Amur cork tree fruit oil * Chinese herbology 50 fundamental herbs * Sān miáo wán


References


External links


Phellodendron amurense

PLANTS Profile for Phellodendron amurense (Amur corktree) , USDA PLANTS

Cortex Phellodendron
{{Taxonbar, from=Q481711 Flora of Northeast Asia Plants used in traditional Chinese medicine Zanthoxyloideae