Amino acid permeases are membrane
permease The permeases are membrane transport proteins, a class of multipass transmembrane proteins that allow the diffusion of a specific molecule in or out of the cell in the direction of a concentration gradient, a form of facilitated diffusion.
The per ...
s involved in the transport of
amino acid
Amino acids are organic compounds that contain both amino and carboxylic acid functional groups. Although hundreds of amino acids exist in nature, by far the most important are the alpha-amino acids, which comprise proteins. Only 22 alpha a ...
s into the cell. A number of such proteins have been found to be evolutionary related.
These proteins contain 12 transmembrane segments.
See also
*
Amino acid transporter
An amino acid transporter is a membrane transport protein that transports amino acids. They are mainly of the solute carrier family.
Families
There are several families that function in amino acid transport, some of these include:
TC# 2.A.3- ...
Human proteins containing this domain
CIP1;
SLC12A1;
SLC12A2
The Na-K-Cl cotransporter (NKCC) is a protein that aids in the secondary active transport of sodium, potassium, and chloride into cells. In humans there are two isoforms of this membrane transport protein, NKCC1 and NKCC2, encoded by two differ ...
;
SLC12A3;
SLC12A4;
SLC12A5;
SLC12A6;
SLC12A7;
SLC12A8;
SLC12A9;
SLC7A1
High affinity cationic amino acid transporter 1 is a protein that in humans is encoded by the ''SLC7A1'' gene
In biology, the word gene (from , ; "...Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." me ...
;
SLC7A10;
SLC7A11
Cystine/glutamate transporter is an antiporter that in humans is encoded by the ''SLC7A11'' gene.
The SLC7A11 gene codes for a sodium-independent cystine- glutamate antiporter that is chloride dependent, known as system Xc- or xCT. It regulate ...
;
SLC7A13;
SLC7A14;
SLC7A2;
SLC7A3;
SLC7A4;
SLC7A5
Large neutral amino acids transporter small subunit 1, also known as 4F2 light chain, or CD98 light chain is a protein that in humans is encoded by the ''SLC7A5'' gene.
See also
* Heterodimeric amino acid transporter
Heterodimeric amino-acid t ...
;
SLC7A6;
SLC7A7;
SLC7A8
Large neutral amino acids transporter small subunit 2 is a protein that in humans is encoded by the ''SLC7A8'' gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity. ...
;
SLC7A9
b(0,+)-type amino acid transporter 1, also known as b(0,+)AT1, is a protein which in humans is encoded by the ''SLC7A9'' gene.
Function
This gene encodes a protein that belongs to a family of light subunits of amino acid transporters. This pro ...
;
References
Protein domains
Protein families
Membrane proteins
{{membrane-protein-stub