Alternative ribosome-rescue factor B (ArfB, YaeJ) also known as peptidyl-tRNA hydrolase,
is a protein that plays a role in rescuing of
stalled ribosomes.
It works like a GGQ-
release factor
A release factor is a protein that allows for the termination of translation by recognizing the termination codon or stop codon in an mRNA sequence. They are named so because they release new peptides from the ribosome.
Background
During t ...
itself, releasing the peptide from tRNA. At the same time, it fits into the mRNA tunnel to remove the mRNA.
This gene is also found in eukaryotic organelles as
MRPL58 (ICT1). The similarity is high enough to be interchangeable. Its role has expanded to that of a codon-independent release factor, although it likely still functions in ribosomal rescue.
See also
* ArfA -
Alternative ribosome-rescue factor A
Alternative ribosome-rescue factor A (ArfA, YhdL) also known as peptidyl-tRNA hydrolase, is a protein that plays a role in rescuing of stalled ribosomes. It recruits RF2.
See also
* ArfB - Alternative ribosome-rescue factor B
References
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References
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Proteins