Algestone (), also known as alphasone or alfasone, as well as dihydroxyprogesterone, is a
progestin which was never marketed.
Another progestin,
algestone acetophenide, in contrast, has been marketed as a
hormonal contraceptive.
Chemistry
Algestone, also known as 16α,17α-dihydroxyprogesterone or as 16α,17α-dihydroxypregn-4-ene-3,20-dione, is a
synthetic pregnane
Pregnane, also known as 17β-ethylandrostane or as 10β,13β-dimethyl-17β-ethylgonane, is a C21 steroid and, indirectly, a parent of progesterone. It is a parent hydrocarbon for two series of steroids stemming from 5α-pregnane (originally allop ...
steroid and a
derivative
In mathematics, the derivative of a function of a real variable measures the sensitivity to change of the function value (output value) with respect to a change in its argument (input value). Derivatives are a fundamental tool of calculus. ...
of
progesterone and
17α-hydroxyprogesterone
17α-Hydroxyprogesterone (17α-OHP), also known as 17-OH progesterone (17-OHP), or hydroxyprogesterone (OHP), is an endogenous progestogen steroid hormone related to progesterone. It is also a chemical intermediate in the biosynthesis of many o ...
.
Closely related
analogues of algestone include
16α-hydroxyprogesterone,
algestone acetonide, and
algestone acetophenide.
References
{{Progesterone receptor modulators
Abandoned drugs
Diketones
Diols
Pregnanes
Progestogens