Alovudine
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Alovudine (fluorothymidine) is an
antiviral Antiviral drugs are a class of medication used for treating viral infections. Most antivirals target specific viruses, while a broad-spectrum antiviral is effective against a wide range of viruses. Unlike most antibiotics, antiviral drugs do no ...
agent which was being developed by
Medivir Medivir is a Swedish biotech company. Medivir focuses its research focus on oncology and particularly on innovative pharmaceuticals that meet substantial unmet medical needs. The pharmaceutical development work is conducted both in-house and thro ...
. It was discontinued after a Phase II trial in 2005 due to toxicity. It is a
DNA polymerase A DNA polymerase is a member of a family of enzymes that catalyze the synthesis of DNA molecules from nucleoside triphosphates, the molecular precursors of DNA. These enzymes are essential for DNA replication and usually work in groups to create ...
inhibitor.


See also

* Fluorothymidine F-18, an isotopically enriched version of alovudine used as a PET tracer


References

Antivirals Pyrimidinediones Organofluorides Abandoned drugs {{antiinfective-drug-stub