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The Alexandria School of Medicine is one of the oldest empirical educational institutions in the history of medicine initiated during the
Hellenistic period In Classical antiquity, the Hellenistic period covers the time in Mediterranean history after Classical Greece, between the death of Alexander the Great in 323 BC and the emergence of the Roman Empire, as signified by the Battle of Actium in 3 ...
in the city of
Alexandria Alexandria ( or ; ar, ٱلْإِسْكَنْدَرِيَّةُ ; grc-gre, Αλεξάνδρεια, Alexándria) is the second largest city in Egypt, and the largest city on the Mediterranean coast. Founded in by Alexander the Great, Alexandria ...
(311 BC). At one historical juncture, in Egypt, they united all the different medical doctrines that originated in the East and in Alexandria (increasingly resembling a cosmopolitan city), and merged into one universal "critical mass of knowledge" the Alexandrian empirical school.'' History & Society: School of Alexandria '
Encyklopedia Britannica
/ref> As the Alexandria School grows more developed Medical Schools in
Knossos Knossos (also Cnossos, both pronounced ; grc, Κνωσός, Knōsós, ; Linear B: ''Ko-no-so'') is the largest Bronze Age archaeological site on Crete and has been called Europe's oldest city. Settled as early as the Neolithic period, the na ...
and in
Knidos Knidos or Cnidus (; grc-gre, Κνίδος, , , Knídos) was a Ancient Greece, Greek city in ancient Caria and part of the Dorian Hexapolis, in south-western Asia Minor, modern-day Turkey. It was situated on the Datça peninsula, which forms the ...
over time lost their meaning and significance.


History

The Greek city of Alexandria, at the mouth of the Nile, was planned and founded by
Alexander the Great Alexander III of Macedon ( grc, wikt:Ἀλέξανδρος, Ἀλέξανδρος, Alexandros; 20/21 July 356 BC – 10/11 June 323 BC), commonly known as Alexander the Great, was a king of the Ancient Greece, ancient Greek kingdom of Maced ...
in 331 BC, and concentrated in it cultural streams from various places: the mysticism of the East and Greek rationalism, in a rich library, with about 700,000 written rolls (the treasure trove of all human knowledge to date, the richest in the world). Thus, with its schools, Alexandria was a kind of university where the most prominent writers, physicians, scientists, and philosophers of the historical period gathered and worked. The ancient Greeks appreciated Egypt and saw in it a mysterious land, fertile with hidden wisdom. At one point, they united all the different medical doctrines originating in the East and in Alexandria (which increasingly resembled a cosmopolitan city) in Egypt, and merged it into one universal critical mass of knowledge. In Alexandria, special importance was given to the study of medicine. The medical works of
Hippocrates Hippocrates of Kos (; grc-gre, Ἱπποκράτης ὁ Κῷος, Hippokrátēs ho Kôios; ), also known as Hippocrates II, was a Greek physician of the classical period who is considered one of the most outstanding figures in the history of ...
and
Aristotle Aristotle (; grc-gre, Ἀριστοτέλης ''Aristotélēs'', ; 384–322 BC) was a Greek philosopher and polymath during the Classical period in Ancient Greece. Taught by Plato, he was the founder of the Peripatetic school of phil ...
were studied and the first "
Hippocratic Corpus The Hippocratic Corpus (Latin: ''Corpus Hippocraticum''), or Hippocratic Collection, is a collection of around 60 early Ancient Greek medical works strongly associated with the physician Hippocrates and his teachings. The Hippocratic Corpus cove ...
" was collected.
Anatomy Anatomy () is the branch of biology concerned with the study of the structure of organisms and their parts. Anatomy is a branch of natural science that deals with the structural organization of living things. It is an old science, having its ...
and methodical study of human corpses are introduced for the first time.


Development of anatomy and physiology

As the medical science of ancient Greece plunged into political decadence and setbacks - scientific work was renewed in this area, especially in the field of anatomy: numerous sections on corpses and even
vivisection Vivisection () is surgery conducted for experimental purposes on a living organism, typically animals with a central nervous system, to view living internal structure. The word is, more broadly, used as a pejorative catch-all term for experiment ...
on
death row Death row, also known as condemned row, is a place in a prison that houses inmates awaiting Capital punishment, execution after being convicted of a capital crime and sentenced to death. The term is also used figuratively to describe the state of ...
inmate A prisoner (also known as an inmate or detainee) is a person who is deprived of liberty against their will. This can be by confinement, captivity, or forcible restraint. The term applies particularly to serving a prison sentence in a prison. ...
s were done. Anatomists and doctors of the Alexandria School were Herophilos and Erasistratus.


Herophilos

Although
Herophilos Herophilos (; grc-gre, Ἡρόφιλος; 335–280 BC), sometimes Latinised Herophilus, was a Greek physician regarded as one of the earliest anatomists. Born in Chalcedon, he spent the majority of his life in Alexandria. He was the first sci ...
() is considered to be the founder of true anatomy, it is also a versatile advocate for the use of medicines. He studied all the organs in the body anatomically, and considered the brain a nerve center and soul-carrier. Herophilos was not only an anatomist but also one of the physicians of that school. He also describes numerous brain structures, which he calls the brain sheaths,
choroid plexus The choroid plexus, or plica choroidea, is a plexus of cells that arises from the tela choroidea in each of the ventricles of the brain. Regions of the choroid plexus produce and secrete most of the cerebrospinal fluid (CSF) of the central nerv ...
and four brain chambers.


Erasistratus

Erasistratus Erasistratus (; grc-gre, Ἐρασίστρατος; c. 304 – c. 250 BC) was a Greek anatomist and royal physician under Seleucus I Nicator of Syria. Along with fellow physician Herophilus, he founded a school of anatomy in Alexandria, where the ...
(304-250 BC), a Greek physician who grew up in
Antioch Antioch on the Orontes (; grc-gre, Ἀντιόχεια ἡ ἐπὶ Ὀρόντου, ''Antiókheia hē epì Oróntou'', Learned ; also Syrian Antioch) grc-koi, Ἀντιόχεια ἡ ἐπὶ Ὀρόντου; or Ἀντιόχεια ἡ ἐπ ...
, was an anatomist of that time, who described the numerous anatomical structures of the human body. He was a young contemporary of
Herophilos Herophilos (; grc-gre, Ἡρόφιλος; 335–280 BC), sometimes Latinised Herophilus, was a Greek physician regarded as one of the earliest anatomists. Born in Chalcedon, he spent the majority of his life in Alexandria. He was the first sci ...
and, with him, the principal representative of the Alexandrian Medical School. He systematically dissected the corpses, the death row convicts, and probably the bodies of living animals, and thus scientifically advanced the anatomy. He described the heart and its
valves A valve is a device or natural object that regulates, directs or controls the flow of a fluid (gases, liquids, fluidized solids, or slurries) by opening, closing, or partially obstructing various passageways. Valves are technically fittings ...
,
blood vessel The blood vessels are the components of the circulatory system that transport blood throughout the human body. These vessels transport blood cells, nutrients, and oxygen to the tissues of the body. They also take waste and carbon dioxide away ...
s and
nerve A nerve is an enclosed, cable-like bundle of nerve fibers (called axons) in the peripheral nervous system. A nerve transmits electrical impulses. It is the basic unit of the peripheral nervous system. A nerve provides a common pathway for the e ...
s, the brain and its chambers and eddies, brain nerve outputs,
lymphatic vessel The lymphatic vessels (or lymph vessels or lymphatics) are thin-walled vessels (tubes), structured like blood vessels, that carry lymph. As part of the lymphatic system, lymph vessels are complementary to the cardiovascular system. Lymph vess ...
s in the
mesentery The mesentery is an organ that attaches the intestines to the posterior abdominal wall in humans and is formed by the double fold of peritoneum. It helps in storing fat and allowing blood vessels, lymphatics, and nerves to supply the intestines ...
and
liver The liver is a major Organ (anatomy), organ only found in vertebrates which performs many essential biological functions such as detoxification of the organism, and the Protein biosynthesis, synthesis of proteins and biochemicals necessary for ...
. However, Erasistratus's greatest merits are in the field of
Physiology Physiology (; ) is the scientific study of functions and mechanisms in a living system. As a sub-discipline of biology, physiology focuses on how organisms, organ systems, individual organs, cells, and biomolecules carry out the chemical ...
. He was the first to correctly describe the physiological functions of ventricular heart valves. Under the influence of the
Democritus Democritus (; el, Δημόκριτος, ''Dēmókritos'', meaning "chosen of the people"; – ) was an Ancient Greek pre-Socratic philosopher from Abdera, primarily remembered today for his formulation of an atomic theory of the universe. No ...
of atomistics and the
peripatetic school The Peripatetic school was a school of philosophy in Ancient Greece. Its teachings derived from its founder, Aristotle (384–322 BC), and ''peripatetic'' is an adjective ascribed to his followers. The school dates from around 335 BC when Aristo ...
, he sought to interpret all life phenomena in a strictly mechanical manner. In his view, three organ systems pass through and are connected by the whole organism: arteries, veins and nerves; the first water
pneuma ''Pneuma'' () is an ancient Greek word for "breath", and in a religious context for "spirit" or "soul". It has various technical meanings for medical writers and philosophers of classical antiquity, particularly in regard to physiology, and is a ...
, the second blood, and the third the nerve fluid. The melting of the pneuma down it was reduced to the mechanical work of the heart. He also tried to explain to the mechanical principles breathing and digestion. The former realized the difference between motor and sensory nerves, and he "threw out"
Hippocrates Hippocrates of Kos (; grc-gre, Ἱπποκράτης ὁ Κῷος, Hippokrátēs ho Kôios; ), also known as Hippocrates II, was a Greek physician of the classical period who is considered one of the most outstanding figures in the history of ...
learning, and advocated the use of weak drugs. Erasistratus rejected the humoral and pathology of the "four juices", starting from the view that the diseases were the result of accumulation of blood (plethora) or its deficiency in some part of the body, which resulted in humoral dyscrasia. According to him, the plethora is a vein full of blood, which flows into the arteries and mechanically expels the pneuma there. As most of the diseases, Erasistratus considered to be due to over-nutrition, he suggested that not much release be used against the plethora blood as a post.


Development of surgery and pharmacology

The Alexandria School leads to the development of surgery and pharmacology. Medicines are prepared there, but at the same time poisons are investigated and antidotes are prepared.


Establishing an empirical school

The flourishing of anatomy in the Alexandrian school led to scientific results that were not always in line with the dogmatic school hypotheses. In response to sterile dogmatism, it originated in the 3 BC in Alexandria the so-called. an empirical school that abandoned assumptions, philosophy and theory, adhering only to experience (empirics) as the only means of acquiring new, positive knowledge.


Glaucko Tarencio

An empiricist school is being developed in Alexandria in parallel. Although the empiricist mode of learning will only gain significance in 17th century when physicians are increasingly seeking success in their work, rather than theoretical knowledge, we find the traces of this teaching in the works of the doctors of the Alexandria School. Its chief representative was the physician Glaucko Tarencio (1 BC), who could be said to have been the forerunner of evidence-based medicine. For him, only results were the reliable basis; acquired through personal experience, or the experience of other physicians, or similar analogy when he did not have prior data to compare from his or her own or others' experience. Of the other greats of this school, one should also mention
Oribasius Oribasius or Oreibasius ( el, Ὀρειβάσιος; c. 320 – 403) was a Greek medical writer and the personal physician of the Roman emperor Julian. He studied at Alexandria under physician Zeno of Cyprus before joining Julian's retinue. He ...
a (6th century), who wrote collected works on medicine in 70 books and
Paul of Aegina Paul of Aegina or Paulus Aegineta ( el, Παῦλος Αἰγινήτης; Aegina, ) was a 7th-century Byzantine Greek physician best known for writing the medical encyclopedia ''Medical Compendium in Seven Books.'' He is considered the “Father ...
(7th century, the most prominent representative of the Byzantine.


Disadvantages of the empirical school

The empirical school had its downsides. The abandonment of the theory caused a decline in the scientific level of medicine, which increasingly began to focus solely on practical problems. The link between physiology and pathology disappeared, and in the end, only the external signs of the disease, the symptoms, were important to the physician at that time.


Alexandrian Medical School Principal of Medical Astrology

The beginnings of
Medical astrology Medical astrology (traditionally known as iatromathematics) is an ancient applied branch of astrology based mostly on ''melothesia'' (Gr. μελοθεσία), the association of various parts of the body, diseases, and drugs with the nature of the ...
are found in the works of physicians and philosophers from the Greco-Alexandrian period. Philosophers, but above all physicians at the Alexandria Medical School, resorted to astrology and valued it as a skill that significantly helps man. With all the differences between astrology and medicine, which are actually skills - '' artes '' (and medicine is actually until the 19th century, although such determination is still heated today), there are significant connections. Both disciplines are based on observation and experience and involve both theoretical and practical aspects. If we take into account the fact that astrology is first and foremost a branch of divination, then it is clear that at least one part of medicine, i.e. prognostics, can be related to astrology. However, if we look back at the history of medicine and start from Greek medicine, we will see that according to many sources, astrology throughout the history of medicine is already a significant part of it
Hippocrates Hippocrates of Kos (; grc-gre, Ἱπποκράτης ὁ Κῷος, Hippokrátēs ho Kôios; ), also known as Hippocrates II, was a Greek physician of the classical period who is considered one of the most outstanding figures in the history of ...
(which respected many astrological rules).Flashar, H., '' Antiquities of the Medizin '', Darmstadt, 1971 The role of astrology in medicine is indicated by a large group of texts in the so-called. popular Hermeticism, a scripture attributed to the legendary Egyptians Neheps and Petoziris and
Hermes Trismegistos Hermes Trismegistus (from grc, Ἑρμῆς ὁ Τρισμέγιστος, "Hermes the Thrice-Greatest"; Classical Latin: la, label=none, Mercurius ter Maximus) is a legendary Hellenistic figure that originated as a syncretic combination of t ...
(who was considered the patron saint of astrology and alchemy), dated as early as 3 BC, in which the connection between astrology and medicine was discovered. In their works they are mainly texts that study the field of botany, mineralogy, but also medicine and medical astrology. In these, certain medicinal plants and minerals, as well as parts of the human body, are associated with zodiac signs, with planets and their positions, etc. In all these astrological-alchemical-magical tracts, the basic assumption is the thesis about the interconnectedness of all parts of the cosmos, the thesis about the operation of the laws of sympathy and antipathy. Astrology plays an important role in medicine, not only in predicting the course of the disease, but also in their treatment. The connection between astrology and medicine is also emphasized in the works of
Claudius Ptolemy Claudius Ptolemy (; grc-gre, Πτολεμαῖος, ; la, Claudius Ptolemaeus; AD) was a mathematician, astronomer, astrologer, geographer, and music theorist, who wrote about a dozen scientific treatises, three of which were of importance ...
(2nd century), especially in those in which astrology, such as the "Quadripartitum and Centiloquium", were works widely used by physicians, which also existed under the name '' Kαρπος '', and which were attributed to and reproduced throughout the Middle Ages and the Renaissance (later, however, this attribution proved to be incorrect).


Loss of importance

With the transition of Egypt to the status of Roman province and the fall of Alexandria into the hands of
Rashidun Caliphate The Rashidun Caliphate ( ar, اَلْخِلَافَةُ ٱلرَّاشِدَةُ, al-Khilāfah ar-Rāšidah) was the first caliphate to succeed the Islamic prophet Muhammad. It was ruled by the first four successive caliphs of Muhammad after his ...
( 641 AD), the Alexandrian Medical School slowly lost importance, while the golden age of medicine in Europe was developing.


References

{{Authority control History of medicine Ancient Alexandria Ancient Greek medicine Universities in Egypt Educational institutions established in the 3rd century BC